Blood and Lymphatic System Quiz
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Questions and Answers

Which of the following is an example of a granulocyte?

  • Monocyte
  • Basophil (correct)
  • Macrophage
  • Lymphocyte
  • All of the above
  • A patient blood sample has an abnormally high number of eosinophils. The likely reason is...

  • Parasitic infection (correct)
  • Internal bleeding
  • Inflammation
  • Allergy
  • Hemoglobin is found in...

  • WBC
  • RBC (correct)
  • Platelets
  • Blood plasma
  • Which of the following is a safe transfusion?

    <p>AB+ to B+</p> Signup and view all the answers

    What antibodies could a person with blood type A- produce?

    <p>Anti-B and Anti-Rh</p> Signup and view all the answers

    A person who is AB+ marries someone who is O+. Which of the following is a possible blood type for their children?

    <p>All of the above are possible</p> Signup and view all the answers

    Match the following blood types with their possible genotypes

    <p>A = IAIA or IAi B = IBIB or IBi AB = IAIB O = ii</p> Signup and view all the answers

    What is the role of the lymphatic system in the body? (Select all that apply)

    <p>The lymphatic system plays a crucial role in maintaining fluid balance, absorbing fats from the digestive tract, and defending the body against disease. It also helps to transport immune cells throughout the body.</p> Signup and view all the answers

    What are the two main types of lymphatic organs, and what are their functions?

    <p>The two main types of lymphatic organs are primary lymphoid organs and secondary lymphoid organs. Primary lymphoid organs, such as the red bone marrow and the thymus, are the sites where immune cells develop. Secondary lymphoid organs, such as the spleen, lymph nodes, and lymphatic nodules, are the sites where the immune response is initiated.</p> Signup and view all the answers

    If you wanted to describe the lymphatic system, which statements would you use?

    <p>All these statements are correct.</p> Signup and view all the answers

    Imagine that lymph is draining from your right arm to return to the heart. Starting with lymphatic capillaries, describe the pathway of lymph flow

    <p>Lymph from your right arm would first pass through lymphatic capillaries, then converge into larger lymphatic valleys. These valleys would then drain into the right lymphatic duct which, in turn, empties into the right subclavian vein. This vein then drains into the right brachiocephalic vein, eventually reaching the superior vena cava and entering the heart.</p> Signup and view all the answers

    Large lymphatic vessels are similar in structure to...

    <p>Veins in the cardiovascular system.</p> Signup and view all the answers

    List and describe two functions of the thymus gland.

    <p>The primary functions of the thymus gland are the maturation of T lymphocytes and the production of thymosins, which are hormones essential for the development of T lymphocytes.</p> Signup and view all the answers

    Which of the following structures has a connective tissue capsule?

    <p>Lymph nodes</p> Signup and view all the answers

    What is the site of stem cells capable of producing blood cells?

    <p>Red bone marrow.</p> Signup and view all the answers

    In an adult, red bone marrow is located in the femur, humerus, vertebrae, ribs, sternum, skull, and part of the pelvic girdle.

    <p>True</p> Signup and view all the answers

    In a child, red bone marrow is found in most bones.

    <p>True</p> Signup and view all the answers

    What are the two primary functions of the thymus?

    <p>The thymus, a primary lymphoid organ, primarily functions in the maturation of T lymphocytes and the production of thymosins, which are hormones crucial for T lymphocyte development.</p> Signup and view all the answers

    What is the function of the spleen?

    <p>The spleen serves as a filter for the blood, removing old or damaged red blood cells. It also acts as a significant site for immune responses by accommodating white blood cells, macrophages, and lymphocytes.</p> Signup and view all the answers

    Lymphatic nodules are concentrations of lymphatic tissue surrounded by a capsule.

    <p>False</p> Signup and view all the answers

    The palatine tonsils are located in the posterior oral cavity.

    <p>True</p> Signup and view all the answers

    The pharyngeal tonsil is also known as adenoid, and it is located in the nasopharynx.

    <p>True</p> Signup and view all the answers

    The lingual tonsils are located at the base of the tongue.

    <p>True</p> Signup and view all the answers

    What type of white blood cell phagocytizes primarily bacteria?

    <p>Neutrophil</p> Signup and view all the answers

    What are the two main categories of leukocytes, and what are their main characteristics?

    <p>The two main categories of leukocytes are granulocytes and agranulocytes. Granulocytes, such as neutrophils, basophils, and eosinophils, have granules in their cytoplasm, which contain enzymes and other substances that help them to fight infection. Agranulocytes, such as lymphocytes and monocytes, lack these granules and play important roles in the immune system.</p> Signup and view all the answers

    Describe the process of the destruction of old red blood cells in the body.

    <p>Macrophages, primarily found in the liver and spleen, engulf old or damaged red blood cells (RBCs). Hemoglobin, a protein in RBCs, is then broken down into its three components: globin, heme, and iron. Globin is digested into amino acids, which are recycled by the body. Iron is returned to the bone marrow for reuse in the production of new RBCs. Heme is converted into bile pigments, bilirubin and biliverdin, which are excreted in bile. These bile pigments are eventually eliminated from the body through the kidneys and digestive tract.</p> Signup and view all the answers

    What is the process that regulates the production of red blood cells?

    <p>Red blood cell production, known as erythropoiesis, is regulated by a hormone called erythropoietin, which is primarily produced by the kidneys. When the oxygen levels in the blood decrease, the kidneys release more erythropoietin. This hormone stimulates the red bone marrow, where red blood cells are produced, to increase the production of new red blood cells. Once oxygen levels return to normal, the kidneys reduce the production of erythropoietin, maintaining a balanced level of red blood cells in the circulatory system.</p> Signup and view all the answers

    The Rh problem is caused by the presence of the Rh factor protein antigen on the RBCs of the fetus and the absence of anti-Rh antibodies in the mother's blood.

    <p>True</p> Signup and view all the answers

    What is the role of Rho-GAM in preventing the Rh problem?

    <p>Rho-GAM is an injection that contains anti-Rh antibodies. It is administered to Rh-negative mothers during pregnancy and within 72 hours after delivery. The antibodies in Rho-GAM destroy any Rh-positive fetal red blood cells that may have entered the mother's bloodstream, preventing the development of anti-Rh antibodies in the mother, thus minimizing the risks associated with the Rh problem in future pregnancies.</p> Signup and view all the answers

    Hemolytic disease of the newborn can occur in which of the following situations?

    <p>Mother: Rh-, Father: Rh+, Fetus: Rh+</p> Signup and view all the answers

    Which of the following blood types is considered a universal donor?

    <p>O-</p> Signup and view all the answers

    Which of the following blood types is considered a universal recipient?

    <p>AB+</p> Signup and view all the answers

    What is the difference between granulocytes and agranulocytes?

    <p>Granulocytes and agranulocytes are two distinct categories of white blood cells. Granulocytes, as their name suggests, contain granules within their cytoplasm, which hold enzymes and other substances essential for fighting infection. Agranulocytes, conversely, lack such granules and have different roles in the immune system. For example, lymphocytes provide specific immunity by generating antibodies or directly killing infected cells.</p> Signup and view all the answers

    What is the significance of the Rh factor in blood transfusions?

    <p>The Rh factor refers to a specific protein found on the surface of red blood cells. It plays a crucial role in blood transfusions, as incompatibility between the Rh factor of the donor and recipient can lead to serious complications. Rh-negative individuals lack the Rh factor protein and can develop anti-Rh antibodies if exposed to Rh-positive blood cells. In subsequent transfusions or pregnancies, these antibodies can cause severe reactions, such as hemolytic anemia.</p> Signup and view all the answers

    In the ABO system, blood type refers to...

    <p>In the ABO system, blood type refers to the inherited antigens present on the surface of red blood cells. These antigens, specifically antigen A and antigen B, determine an individual's blood type, which is crucial for safe blood transfusions and understanding potential incompatibilities.</p> Signup and view all the answers

    What are the three alleles responsible for the ABO blood type system, and what do they represent?

    <p>The ABO blood group system is determined by three alleles: IA, IB, and i. The IA allele expresses antigen A, the IB allele expresses antigen B, and the i allele represents no antigen. These alleles combine in various combinations to produce the four different blood types: type A, type B, type AB, and type O.</p> Signup and view all the answers

    Study Notes

    Blood and Lymphatic System

    • Blood is approximately 5 liters in an average 70kg individual
    • Blood is a protein-rich fluid with cellular components
    • Plasma (~55%) is the protein-rich portion of blood
    • Formed elements (~45%) are the cellular components of blood
    • Formed elements include leukocytes and platelets (<1% of whole blood) and erythrocytes (45% of whole blood)
    • Blood is composed primarily of water (90-92%)
    • Blood also contains dissolved ions, nutrients, waste products, and proteins
    • Albumin is the most abundant plasma protein and maintains blood osmotic pressure.
    • Fibrinogen and Prothrombin are necessary for blood clotting
    • Antibodies are necessary for immune defense.
    • Red blood cells (RBCs) transport oxygen and carbon dioxide. Hemoglobin binds to O2 and CO2. RBCs are biconcave in shape, enabling more surface area for gas exchange. There are 4 to 6 million RBCs per mm³ of whole blood. Lower numbers of RBCs, or hemoglobin, is called anemia.
    • White blood cells (WBCs) defend the body against pathogens, destroy dead/dying body cells, and recognize/kill cancerous cells. WBCs are called leukocytes, and there are 5,000-11,000 per mm³ of blood
    • Platelets (thrombocytes) function in blood clotting, are formed from fragmentation of megakaryocytes, and last for about 10 days. Platelets are produced at a rate of 200 billion per day.

    Blood Plasma Components

    • Water (91-92%) is the solvent
    • Plasma proteins (albumin, globulins, fibrinogen) regulate blood osmotic pressure and are involved in defense and clotting
    • Ions, sugars, and other substances aid metabolism, cell and tissue function, nutrition, and respiration.

    Blood - Formed Elements

    • Erythrocytes: Transport oxygen and carbon dioxide, contain hemoglobin. 4-6 million per mm³
    • Leukocytes: Fight infection, destroy dead/dying cells, and recognize/kill cancerous cells, and are 5,000-11,000 per mm³
    • Platelets: Involved in blood clotting, 150,000-300,000 per mm³

    Hematopoiesis

    • Multipotent stem cells divide to produce specific stem cells (myeloid and lymphoid).
    • Myeloid stem cells produce RBCs, platelets, and most WBCs.
    • Lymphoid stem cells produce lymphocytes.

    Red Blood Cell Regulation

    • Kidneys release erythropoietin (EPO) when blood oxygen levels are low.
    • EPO stimulates red bone marrow to increase RBC production.
    • When blood oxygen levels increase to normal, EPO production decreases.

    Red Blood Cell Destruction

    • Macrophages engulf and destroy old or damaged RBCs.
    • Hemoglobin is broken down into amino acids, iron, and heme.
    • Iron is recycled to the bone marrow.
    • Heme is converted into bile pigments, which are eliminated in the bile.

    White Blood Cells (WBCs)

    • Also known as leukocytes
    • Different types with various functions (granulocytes and agranulocytes)

    Granular Leukocytes

    • Neutrophils: Multi-lobed nuclei, phagocytose pathogens
    • Eosinophils: Bi-lobed nuclei, combat parasitic worms, and participate in allergic responses
    • Basophils: U-shaped nuclei, release histamine and heparin

    Agranular Leukocytes

    • Lymphocytes: Spherical nuclei, provide specific immunity to pathogens. There are two types: B and T.
    • Monocytes: Kidney-shaped nuclei, become macrophages after migrating to tissues, engulf pathogens, and cellular debris. They are the largest WBCs

    Platelets (Thrombocytes)

    • Formed from fragmentation of megakaryocytes
    • Involved in blood clotting
    • Produced at a rate of 200 billion per day
    • Have no nucleus
    • Last about ten days

    Lymphatic System

    • Consists of lymphatic vessels and lymphatic organs.
    • Fluid balance: takes up excess interstitial fluid and returns it to the bloodstream.
    • Fat absorption: absorbs fats from the digestive tract and transports them to the bloodstream.
    • Defense: helps defend the body against disease.

    Lymphatic Vessels

    • Begin with close-ended lymphatic capillaries with large pores allowing particles to enter.
    • Larger lymphatic vessels have valves to regulate lymph flow.
    • Lymph movement largely depends on skeletal muscle contractions.
    • Lymphatic vessels merge to form larger vessels that empty into one of two ducts: thoracic duct or right lymphatic duct.
    • Lymph from the right side of the body & right upper limb drains into the right subclavian vein.
    • Lymph from the lower body, the left side of the head & neck, and left upper limb drains into the left subclavian vein.

    Lymphatic Organs (Primary)

    • Thymus: Site of T cell maturation.
    • Red bone marrow: Site of blood cell production, including stem cells capable of producing blood cells; limited in adults.

    Lymphatic Organs (Secondary)

    • Lymph node: Filters lymph, and location for lymphocytes to fight infections and attack cancer cells.
    • Spleen: Functions as a blood reservoir and removes dead/dying blood cells
    • Lymphatic nodules: concentrations of lymphatic tissues that help defend against pathogens (includes tonsils, Peyer's patches, and the appendix).

    Blood Types

    • ABO blood typing is based on the presence or absence of antigens A and B on the surface of red blood cells (RBCs).
    • Type A blood has type A antigens and anti-B antibodies
    • Type B blood has type B antigens and anti-A antibodies
    • Type AB blood has type A and B antigens and no antibodies
    • Type O blood has neither A nor B antigens, and both anti-A and anti-B antibodies
    • Rh factor: another important blood group system, presence or absence of the Rh antigen on RBCs affects compatibility.

    Hemolytic Disease of the Newborn

    • Occurs when an Rh-negative mother carries an Rh-positive fetus.
    • Maternal antibodies against the Rh factor attack fetal RBCs, causing hemolysis.
    • Prevented by injections of RhoGAM to the mother during pregnancy and after delivery.

    Blood Typing Tests

    • Blood samples are tested with antibodies against A, B, and Rh antigens to determine blood type. Observed reactions provide the definitive diagnosis.

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    Description

    Test your knowledge on the components and functions of the blood and lymphatic system. This quiz covers topics such as blood composition, cellular elements, and the roles of various proteins. Perfect for students studying biology or health sciences.

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