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Questions and Answers
Which of the following is NOT a function of blood?
Which of the following is NOT a function of blood?
The color of blood is primarily determined by which component?
The color of blood is primarily determined by which component?
What is the approximate percentage of plasma in the average adult's blood volume?
What is the approximate percentage of plasma in the average adult's blood volume?
Which of the following is NOT a major area of bone marrow involved in blood cell formation?
Which of the following is NOT a major area of bone marrow involved in blood cell formation?
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What is the primary function of platelets in blood?
What is the primary function of platelets in blood?
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Which type of bone marrow is primarily responsible for the production of red blood cells?
Which type of bone marrow is primarily responsible for the production of red blood cells?
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What is the approximate concentration of albumin in plasma?
What is the approximate concentration of albumin in plasma?
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Which of the following is NOT a substance found in plasma?
Which of the following is NOT a substance found in plasma?
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Which type of white blood cell is responsible for engulfing and digesting bacteria, and is nicknamed a 'microphage'?
Which type of white blood cell is responsible for engulfing and digesting bacteria, and is nicknamed a 'microphage'?
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Which of the following statements accurately describes the role of lymphocytes in the immune system?
Which of the following statements accurately describes the role of lymphocytes in the immune system?
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Which type of white blood cell is most prevalent in the blood, accounting for approximately 60% of the total white blood cell count?
Which type of white blood cell is most prevalent in the blood, accounting for approximately 60% of the total white blood cell count?
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Which white blood cell type is involved in defending against parasitic infections?
Which white blood cell type is involved in defending against parasitic infections?
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Which of the following is NOT a granulocyte?
Which of the following is NOT a granulocyte?
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Which of the following statements describes the role of monocytes in the immune system?
Which of the following statements describes the role of monocytes in the immune system?
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Which of the following circumstances would NOT typically lead to an increase in white blood cell count?
Which of the following circumstances would NOT typically lead to an increase in white blood cell count?
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Which type of white blood cell plays a crucial role in allergic reactions?
Which type of white blood cell plays a crucial role in allergic reactions?
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Which of the following is NOT a direct result of the increased storage of hemoglobin in red blood cells?
Which of the following is NOT a direct result of the increased storage of hemoglobin in red blood cells?
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Which of the following is TRUE about the production of erythropoietin in the human body?
Which of the following is TRUE about the production of erythropoietin in the human body?
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What is the role of iron in the process of oxygen transport in the human body?
What is the role of iron in the process of oxygen transport in the human body?
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Based on the information provided, which of these statements about blood groups is INCORRECT?
Based on the information provided, which of these statements about blood groups is INCORRECT?
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Considering both the information about erythropoietin and blood groups, what is the most direct link between these two concepts?
Considering both the information about erythropoietin and blood groups, what is the most direct link between these two concepts?
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Which of the following statements accurately describes the process of erythropoiesis in humans?
Which of the following statements accurately describes the process of erythropoiesis in humans?
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What is the primary function of the red blood cells in the human body?
What is the primary function of the red blood cells in the human body?
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Considering the information provided, why is the presence of iron in hemoglobin important?
Considering the information provided, why is the presence of iron in hemoglobin important?
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Which type of immunity is responsible for the body's defense against a specific pathogen, such as a particular virus, that the body has encountered before?
Which type of immunity is responsible for the body's defense against a specific pathogen, such as a particular virus, that the body has encountered before?
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What type of immunity is primarily responsible for the defense against viruses and tumor cells through the action of lymphocytes that attach to these cells?
What type of immunity is primarily responsible for the defense against viruses and tumor cells through the action of lymphocytes that attach to these cells?
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Which type of immunity would be most affected if the thymus gland were to be removed?
Which type of immunity would be most affected if the thymus gland were to be removed?
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What is the primary function of antibodies in the immune system?
What is the primary function of antibodies in the immune system?
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Which of the following immune system components is responsible for the production of antibodies?
Which of the following immune system components is responsible for the production of antibodies?
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Which statement BEST describes the relationship between humoral and adaptive immunity?
Which statement BEST describes the relationship between humoral and adaptive immunity?
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Which of the following is NOT a component of the innate immune system?
Which of the following is NOT a component of the innate immune system?
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Which type of immunity is responsible for the protection a newborn baby receives from its mother through breast milk?
Which type of immunity is responsible for the protection a newborn baby receives from its mother through breast milk?
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Which of the following is NOT a characteristic of a white thrombus?
Which of the following is NOT a characteristic of a white thrombus?
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What is the primary role of fibrinogen in the blood coagulation process?
What is the primary role of fibrinogen in the blood coagulation process?
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Which of the following is an example of an acquired immune deficiency?
Which of the following is an example of an acquired immune deficiency?
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What is the main function of platelets in the blood coagulation process?
What is the main function of platelets in the blood coagulation process?
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Which of the following is NOT a physiological anticoagulant?
Which of the following is NOT a physiological anticoagulant?
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Which of the following best describes the role of plasmin in the blood coagulation process?
Which of the following best describes the role of plasmin in the blood coagulation process?
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Which of the following is a characteristic of hypersensitivity?
Which of the following is a characteristic of hypersensitivity?
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Which of the following events is NOT a part of the four major events of haemostasis?
Which of the following events is NOT a part of the four major events of haemostasis?
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What is a primary distinction between primary and secondary polycythemia?
What is a primary distinction between primary and secondary polycythemia?
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Which of these is NOT a common cause of secondary polycythemia?
Which of these is NOT a common cause of secondary polycythemia?
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Which of the following is NOT a symptom of polycythemia?
Which of the following is NOT a symptom of polycythemia?
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Which of the following scenarios could lead to a condition known as purpura?
Which of the following scenarios could lead to a condition known as purpura?
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A patient presenting with severe bleeding, inherited as a sex-linked disorder, most likely suffers from which condition?
A patient presenting with severe bleeding, inherited as a sex-linked disorder, most likely suffers from which condition?
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What is the main defining factor that differentiates between Haemophilia A, B, and C?
What is the main defining factor that differentiates between Haemophilia A, B, and C?
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Which of the following factors is NOT released by the body during an inflammatory response?
Which of the following factors is NOT released by the body during an inflammatory response?
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A person with a deficiency in folate intake is likely to be at an increased risk for which of the following conditions?
A person with a deficiency in folate intake is likely to be at an increased risk for which of the following conditions?
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Flashcards
Platelets
Platelets
Specialized cells in blood that help clotting.
Plasma
Plasma
Liquid component of blood, about 54.3% of total blood volume.
Haematopoiesis
Haematopoiesis
The formation of blood cellular components from stem cells.
Bone Marrow
Bone Marrow
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Erythrocytes
Erythrocytes
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pH Regulation
pH Regulation
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Blood Composition
Blood Composition
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Blood Temperature Regulation
Blood Temperature Regulation
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Blood groups
Blood groups
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White blood cells (WBC)
White blood cells (WBC)
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Granulocytes
Granulocytes
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Agranulocytes
Agranulocytes
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Neutrophils
Neutrophils
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Eosinophils
Eosinophils
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Lymphocytes
Lymphocytes
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Immunity
Immunity
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Haemoglobin
Haemoglobin
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Erythropoiesis
Erythropoiesis
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Erythropoietin (EPO)
Erythropoietin (EPO)
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ABO Blood Group System
ABO Blood Group System
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Antigens
Antigens
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Antibodies (Agglutinins)
Antibodies (Agglutinins)
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Iron in Blood
Iron in Blood
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Immune System
Immune System
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Innate Immunity
Innate Immunity
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Adaptive Immunity
Adaptive Immunity
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Passive Immunity
Passive Immunity
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Humoral Immunity
Humoral Immunity
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Immunoglobulin G (IgG)
Immunoglobulin G (IgG)
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Vitamin B12 deficiency
Vitamin B12 deficiency
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Folic acid deficiency
Folic acid deficiency
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Anaemia
Anaemia
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Polycythaemia
Polycythaemia
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Hypercoagulable disorders
Hypercoagulable disorders
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Hypocoagulable disorders
Hypocoagulable disorders
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Haemophilia
Haemophilia
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Inflammation
Inflammation
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Immune Deficiency
Immune Deficiency
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AIDS
AIDS
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Hypersensitivity
Hypersensitivity
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Autoimmune Disease
Autoimmune Disease
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Platelet Activation
Platelet Activation
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Haemostasis
Haemostasis
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Fibrin Mesh
Fibrin Mesh
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Anticoagulants
Anticoagulants
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Study Notes
Blood Physiology
- Blood is a specialized bodily fluid that circulates in arteries and veins.
- It's a fluid connective tissue.
- Blood comprises around 55% plasma and 45% formed elements.
- Plasma transports blood cells, proteins, electrolytes, hormones, and nutrients throughout the body.
- Plasma brings waste products from tissues to the urinary system.
- Blood has three main types of blood cells with significant functions.
- Red blood cells (erythrocytes) carry oxygen from lungs to body.
- White blood cells (leukocytes) protect against pathogens (disease-causing organisms).
- Platelets (thrombocytes) clump together to repair broken blood vessels.
Blood Composition
- Blood is composed of:
- Plasma (55%): Liquid component, primarily water.
- Formed Elements (45%):
- Red blood cells (erythrocytes)
- White blood cells (leukocytes)
- Granulocytes (neutrophils, eosinophils, basophils)
- Agranulocytes (monocytes, lymphocytes)
- Platelets (thrombocytes)
- Hemoglobin is the principal determinant of blood color
Blood Cell Development
- Blood cells produced in bone marrow.
- Two types of marrow: Red (active) and yellow (inactive).
- Stem cells differentiate into various blood cells.
Hematopoiesis
- The process of blood cell formation.
- Multipotential hematopoietic stem cells (hemocytoblasts) are the precursors to all blood cells.
- Common myeloid and lymphoid progenitors.
- Erythropoiesis, the formation of red blood cells
- Leukopoiesis, the formation of white blood cells
Red Blood Cells (RBCs)
- Erythrocytes are anucleated.
- Their main function is oxygen transport.
- Hemoglobin is a respiratory pigment.
- Hemoglobin carries oxygen and carbon dioxide.
- In humans, erythropoiesis mostly happens in bone marrow.
- In early fetal development, it happens in the yolk sac and later in the liver.
- Hemoglobin is comprised of iron, giving blood its red color.
Erythropoietin
- A glycoprotein hormone.
- Controls erythropoiesis (red blood cell production).
- Primarily produced in kidneys.
Blood Groups
- ABO system: Four main blood types (A, B, AB, O).
- Rh system: Positive (Rh+) or Negative (Rh-).
- Blood transfusions should consider blood type compatibility to avoid clotting or hemolysis.
- There are two main types of antigens.
Blood Group System
- Blood types A, B, AB and O
- Antigen A on surface of red blood cells
- Antigen B on surface of red blood cells
- Antibodies for the opposing blood groups
- The presence or absence of hereditary antigen substances on red blood cells.
- Plasma contains antibodies to antigens that are not present.
Rh Blood Group System
- Important for blood transfusions.
- Rh factor (antigen D) presence determines positive or negative type.
- Compatibility critical to avoid problems during transfusions
Blood Transfusion
- Precautions to avoid reactions.
- Compatibility testing is crucial (ABO, Rh testing).
- Blood must be fresh and stored properly.
White Blood Cells (WBCs)
- Leukocytes.
- Protect against infections.
- Types: Granulocytes (neutrophils, eosinophils, basophils) and Agranulocytes (lymphocytes, monocytes).
- Different types have different roles in the infection response and immune system.
Immunity
- Ability of the body to resist or fight off organisms that cause disease, such as bacteria, viruses or parasites
- Innate immunity: Born with this
- Adaptive immunity: Develops over time after exposure to germs
- Passive immunity: Temporary borrowed immunity from another source
Immune Abnormalities
- Immune deficiency (failure of the immune system to work properly).
- Hypersensitivity (allergies or autoimmune diseases).
- Autoimmune diseases are when your body's immune system attacks healthy cells and tissues.
- Such as asthma, urticaria and AIDS
Platelets and Blood Coagulation
- Platelets (thrombocytes) are essential for blood clotting.
- Blood coagulation: The process of forming clots in damaged blood vessels to stop bleeding.
- Hemostasis: The entire process of stopping bleeding (vascular constriction, platelet plug, blood clot formation and clot dissolution).
- Factors involved in blood coagulation: Various proteins and factors.
Anticoagulants
- Chemicals that prevent blood clots.
- Physiological & therapeutic types, such as Vitamin K antagonists, direct oral anticoagulants (DOACs), and low-molecular-weight heparins (LMWHs).
- Maintaining blood flow is crucial to prevent blockage
Blood Disorders
- Anemia: Low red blood cell count or reduced hemoglobin
- Polycythemia: High red blood cell count
Disorders of Haemostasis
- Hypercoagulable disorders are where blood clots too easily.
- Hypocoagulable disorders are where blood clots too slowly.
- Bleeding disorders are where an individual cannot form blood clots effectively.
Inflammation
- Localized physical condition from injury.
- Redness, swelling, heat, and pain are common signs.
- Chemicals such as histamine, serotonin and bradykinin are involved.
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Description
Test your knowledge about the functions of blood, its components, and the various types of blood cells. This quiz covers topics including plasma, platelets, and different white blood cells involved in the immune system. Answer the questions to learn more about the crucial roles blood plays in our body.