Blood and Its Functions Quiz
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Questions and Answers

Which of the following is NOT a function of blood?

  • Transportation of hormones
  • Regulation of body temperature
  • Regulation of pH levels
  • Production of red blood cells (correct)
  • The color of blood is primarily determined by which component?

  • White blood cells
  • Plasma
  • Haemoglobin (correct)
  • Platelets
  • What is the approximate percentage of plasma in the average adult's blood volume?

  • 45%
  • 54.3% (correct)
  • 8%
  • 0.7%
  • Which of the following is NOT a major area of bone marrow involved in blood cell formation?

    <p>Liver (A)</p> Signup and view all the answers

    What is the primary function of platelets in blood?

    <p>Blood clotting (B)</p> Signup and view all the answers

    Which type of bone marrow is primarily responsible for the production of red blood cells?

    <p>Red marrow (C)</p> Signup and view all the answers

    What is the approximate concentration of albumin in plasma?

    <p>35-50 mg/ml (D)</p> Signup and view all the answers

    Which of the following is NOT a substance found in plasma?

    <p>Red blood cells (A)</p> Signup and view all the answers

    Which type of white blood cell is responsible for engulfing and digesting bacteria, and is nicknamed a 'microphage'?

    <p>Neutrophils (B)</p> Signup and view all the answers

    Which of the following statements accurately describes the role of lymphocytes in the immune system?

    <p>Lymphocytes produce antibodies that specifically target foreign invaders. (A)</p> Signup and view all the answers

    Which type of white blood cell is most prevalent in the blood, accounting for approximately 60% of the total white blood cell count?

    <p>Neutrophils (A)</p> Signup and view all the answers

    Which white blood cell type is involved in defending against parasitic infections?

    <p>Eosinophils (D)</p> Signup and view all the answers

    Which of the following is NOT a granulocyte?

    <p>Lymphocytes (C)</p> Signup and view all the answers

    Which of the following statements describes the role of monocytes in the immune system?

    <p>Monocytes are capable of engulfing large numbers of bacteria within tissues. (B)</p> Signup and view all the answers

    Which of the following circumstances would NOT typically lead to an increase in white blood cell count?

    <p>Normal digestion of food (A)</p> Signup and view all the answers

    Which type of white blood cell plays a crucial role in allergic reactions?

    <p>Basophils (B)</p> Signup and view all the answers

    Which of the following is NOT a direct result of the increased storage of hemoglobin in red blood cells?

    <p>Increased production of red blood cells by the bone marrow. (A)</p> Signup and view all the answers

    Which of the following is TRUE about the production of erythropoietin in the human body?

    <p>The kidneys and liver both contribute to erythropoietin production, but their relative contribution changes with age. (C)</p> Signup and view all the answers

    What is the role of iron in the process of oxygen transport in the human body?

    <p>Iron acts as a direct binding site for oxygen, allowing it to be transported by hemoglobin. (B)</p> Signup and view all the answers

    Based on the information provided, which of these statements about blood groups is INCORRECT?

    <p>Plasma usually contains antibodies against the antigen present on the surface of red blood cells. (C)</p> Signup and view all the answers

    Considering both the information about erythropoietin and blood groups, what is the most direct link between these two concepts?

    <p>Erythropoietin regulates the production of red blood cells, contributing to the overall number of red blood cells that express specific antigens. (A)</p> Signup and view all the answers

    Which of the following statements accurately describes the process of erythropoiesis in humans?

    <p>Erythropoiesis begins in the yolk sac and gradually shifts to the liver before finally transitioning to the bone marrow. (D)</p> Signup and view all the answers

    What is the primary function of the red blood cells in the human body?

    <p>Red blood cells transport oxygen from the lungs to the tissues and remove carbon dioxide from the body. (D)</p> Signup and view all the answers

    Considering the information provided, why is the presence of iron in hemoglobin important?

    <p>Iron directly binds to oxygen molecules, facilitating their transport throughout the body. (A)</p> Signup and view all the answers

    Which type of immunity is responsible for the body's defense against a specific pathogen, such as a particular virus, that the body has encountered before?

    <p>Adaptive (Acquired) Immunity (A)</p> Signup and view all the answers

    What type of immunity is primarily responsible for the defense against viruses and tumor cells through the action of lymphocytes that attach to these cells?

    <p>Innate Immunity (B)</p> Signup and view all the answers

    Which type of immunity would be most affected if the thymus gland were to be removed?

    <p>Acquired Immunity (B)</p> Signup and view all the answers

    What is the primary function of antibodies in the immune system?

    <p>Binding to specific antigens, marking them for destruction (D)</p> Signup and view all the answers

    Which of the following immune system components is responsible for the production of antibodies?

    <p>B lymphocytes (D)</p> Signup and view all the answers

    Which statement BEST describes the relationship between humoral and adaptive immunity?

    <p>Humoral immunity is a subset of adaptive immunity, mediated by antibodies produced by B lymphocytes. (C)</p> Signup and view all the answers

    Which of the following is NOT a component of the innate immune system?

    <p>Antibodies (A)</p> Signup and view all the answers

    Which type of immunity is responsible for the protection a newborn baby receives from its mother through breast milk?

    <p>Passive Immunity (A)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of a white thrombus?

    <p>It is composed of red blood cells and platelets. (C)</p> Signup and view all the answers

    What is the primary role of fibrinogen in the blood coagulation process?

    <p>It stimulates platelet clumping and forms the fibrin mesh. (B)</p> Signup and view all the answers

    Which of the following is an example of an acquired immune deficiency?

    <p>Acquired Immune Deficiency Syndrome (AIDS) (C)</p> Signup and view all the answers

    What is the main function of platelets in the blood coagulation process?

    <p>To bind to damaged blood vessels and form a temporary plug. (A)</p> Signup and view all the answers

    Which of the following is NOT a physiological anticoagulant?

    <p>Heparin (C)</p> Signup and view all the answers

    Which of the following best describes the role of plasmin in the blood coagulation process?

    <p>It dissolves the clot after tissue repair. (C)</p> Signup and view all the answers

    Which of the following is a characteristic of hypersensitivity?

    <p>Excessive immune response to an antigen. (A)</p> Signup and view all the answers

    Which of the following events is NOT a part of the four major events of haemostasis?

    <p>Release of histamine by mast cells. (D)</p> Signup and view all the answers

    What is a primary distinction between primary and secondary polycythemia?

    <p>Primary polycythemia is typically a genetic disorder, whereas secondary polycythemia is acquired. (C)</p> Signup and view all the answers

    Which of these is NOT a common cause of secondary polycythemia?

    <p>Tumour like condition (B)</p> Signup and view all the answers

    Which of the following is NOT a symptom of polycythemia?

    <p>Excessive bleeding (D)</p> Signup and view all the answers

    Which of the following scenarios could lead to a condition known as purpura?

    <p>An abnormal function of platelets. (D)</p> Signup and view all the answers

    A patient presenting with severe bleeding, inherited as a sex-linked disorder, most likely suffers from which condition?

    <p>Hemophilia (B)</p> Signup and view all the answers

    What is the main defining factor that differentiates between Haemophilia A, B, and C?

    <p>The specific clotting factor that is deficient. (C)</p> Signup and view all the answers

    Which of the following factors is NOT released by the body during an inflammatory response?

    <p>Factor VIII (D)</p> Signup and view all the answers

    A person with a deficiency in folate intake is likely to be at an increased risk for which of the following conditions?

    <p>Anemia (A)</p> Signup and view all the answers

    Flashcards

    Platelets

    Specialized cells in blood that help clotting.

    Plasma

    Liquid component of blood, about 54.3% of total blood volume.

    Haematopoiesis

    The formation of blood cellular components from stem cells.

    Bone Marrow

    A jellylike substance in bones where blood cells are produced.

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    Erythrocytes

    Another name for red blood cells, which carry oxygen.

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    pH Regulation

    Blood regulates acidity levels in the body.

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    Blood Composition

    Blood consists of red cells, plasma, white cells, and platelets.

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    Blood Temperature Regulation

    Blood flow changes to control body temperature.

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    Blood groups

    Types of blood classified by specific antigens, including A, B, AB, and O.

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    White blood cells (WBC)

    Colorless blood cells that help fight infections; normal range is 4,000 to 11,000/ml.

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    Granulocytes

    A type of WBC with visible granules; includes neutrophils, eosinophils, and basophils.

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    Agranulocytes

    A type of WBC without visible granules; includes monocytes and lymphocytes.

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    Neutrophils

    The most common type of WBC (60%); they attack and destroy bacteria.

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    Eosinophils

    WBCs (3%) that defend against parasites and play a role in allergy responses.

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    Lymphocytes

    WBCs (30%) involved in specific immunity, including T and B cells.

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    Immunity

    The body's ability to resist harmful organisms or toxins.

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    Haemoglobin

    A respiratory pigment in red blood cells that binds oxygen or carbon dioxide.

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    Erythropoiesis

    The production of red blood cells occurring mainly in the bone marrow.

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    Erythropoietin (EPO)

    A glycoprotein hormone that controls the production of red blood cells.

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    ABO Blood Group System

    A blood classification system determined by the presence of A and B antigens.

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    Antigens

    Inherited substances on the surface of red blood cells that determine blood type.

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    Antibodies (Agglutinins)

    Proteins present in plasma that attack foreign antigens.

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    Iron in Blood

    Component of haemoglobin that binds with oxygen and gives blood its red color.

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    Immune System

    The body's defense network against infections.

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    Innate Immunity

    The immunity we are born with that responds immediately to invaders.

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    Adaptive Immunity

    Immunity that develops over time after exposure to pathogens.

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    Passive Immunity

    Temporary immunity gained from another person, such as a mother.

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    Humoral Immunity

    Immunity mediated by antibodies in the blood.

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    Immunoglobulin G (IgG)

    The most abundant antibody that can cross the placenta.

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    Vitamin B12 deficiency

    Insufficient Vitamin B12 due to poor intake or absorption.

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    Folic acid deficiency

    Insufficient folic acid due to poor intake or increased need.

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    Anaemia

    Condition marked by low RBC count leading to reduced oxygen supply.

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    Polycythaemia

    Abnormal increase in red blood cells (RBCs), causing higher blood viscosity.

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    Hypercoagulable disorders

    Conditions causing excessive blood clotting within vessels.

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    Hypocoagulable disorders

    Conditions causing insufficient blood clotting; spontaneous bleeding occurs.

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    Haemophilia

    Inherited bleeding disorder due to deficiency in clotting factors.

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    Inflammation

    Localized bodily reaction marked by redness, warmth, swelling, and pain due to injury.

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    Immune Deficiency

    A failure of the immune system to function properly, can be congenital or acquired.

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    AIDS

    Acquired Immune Deficiency Syndrome, a disease caused by the human immunodeficiency virus (HIV).

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    Hypersensitivity

    An exaggerated immune response to an antigen, causing conditions like asthma or allergies.

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    Autoimmune Disease

    A condition where the body's immune system mistakenly attacks its own cells.

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    Platelet Activation

    The process where platelets become active and aggregate at injury sites to help form clots.

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    Haemostasis

    The process of stopping bleeding, involving blood clotting and subsequent clot removal.

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    Fibrin Mesh

    A stable network formed by fibrin that traps platelets and red blood cells to stabilize a clot.

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    Anticoagulants

    Substances that inhibit clot formation, which can be physiological or therapeutic.

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    Study Notes

    Blood Physiology

    • Blood is a specialized bodily fluid that circulates in arteries and veins.
    • It's a fluid connective tissue.
    • Blood comprises around 55% plasma and 45% formed elements.
    • Plasma transports blood cells, proteins, electrolytes, hormones, and nutrients throughout the body.
    • Plasma brings waste products from tissues to the urinary system.
    • Blood has three main types of blood cells with significant functions.
    • Red blood cells (erythrocytes) carry oxygen from lungs to body.
    • White blood cells (leukocytes) protect against pathogens (disease-causing organisms).
    • Platelets (thrombocytes) clump together to repair broken blood vessels.

    Blood Composition

    • Blood is composed of:
      • Plasma (55%): Liquid component, primarily water.
      • Formed Elements (45%):
        • Red blood cells (erythrocytes)
        • White blood cells (leukocytes)
          • Granulocytes (neutrophils, eosinophils, basophils)
          • Agranulocytes (monocytes, lymphocytes)
        • Platelets (thrombocytes)
    • Hemoglobin is the principal determinant of blood color

    Blood Cell Development

    • Blood cells produced in bone marrow.
    • Two types of marrow: Red (active) and yellow (inactive).
    • Stem cells differentiate into various blood cells.

    Hematopoiesis

    • The process of blood cell formation.
    • Multipotential hematopoietic stem cells (hemocytoblasts) are the precursors to all blood cells.
    • Common myeloid and lymphoid progenitors.
    • Erythropoiesis, the formation of red blood cells
    • Leukopoiesis, the formation of white blood cells

    Red Blood Cells (RBCs)

    • Erythrocytes are anucleated.
    • Their main function is oxygen transport.
    • Hemoglobin is a respiratory pigment.
    • Hemoglobin carries oxygen and carbon dioxide.
    • In humans, erythropoiesis mostly happens in bone marrow.
    • In early fetal development, it happens in the yolk sac and later in the liver.
    • Hemoglobin is comprised of iron, giving blood its red color.

    Erythropoietin

    • A glycoprotein hormone.
    • Controls erythropoiesis (red blood cell production).
    • Primarily produced in kidneys.

    Blood Groups

    • ABO system: Four main blood types (A, B, AB, O).
    • Rh system: Positive (Rh+) or Negative (Rh-).
    • Blood transfusions should consider blood type compatibility to avoid clotting or hemolysis.
    • There are two main types of antigens.

    Blood Group System

    • Blood types A, B, AB and O
    • Antigen A on surface of red blood cells
    • Antigen B on surface of red blood cells
    • Antibodies for the opposing blood groups
    • The presence or absence of hereditary antigen substances on red blood cells.
    • Plasma contains antibodies to antigens that are not present.

    Rh Blood Group System

    • Important for blood transfusions.
    • Rh factor (antigen D) presence determines positive or negative type.
    • Compatibility critical to avoid problems during transfusions

    Blood Transfusion

    • Precautions to avoid reactions.
    • Compatibility testing is crucial (ABO, Rh testing).
    • Blood must be fresh and stored properly.

    White Blood Cells (WBCs)

    • Leukocytes.
    • Protect against infections.
    • Types: Granulocytes (neutrophils, eosinophils, basophils) and Agranulocytes (lymphocytes, monocytes).
    • Different types have different roles in the infection response and immune system.

    Immunity

    • Ability of the body to resist or fight off organisms that cause disease, such as bacteria, viruses or parasites
    • Innate immunity: Born with this
    • Adaptive immunity: Develops over time after exposure to germs
    • Passive immunity: Temporary borrowed immunity from another source

    Immune Abnormalities

    • Immune deficiency (failure of the immune system to work properly).
    • Hypersensitivity (allergies or autoimmune diseases).
    • Autoimmune diseases are when your body's immune system attacks healthy cells and tissues.
    • Such as asthma, urticaria and AIDS

    Platelets and Blood Coagulation

    • Platelets (thrombocytes) are essential for blood clotting.
    • Blood coagulation: The process of forming clots in damaged blood vessels to stop bleeding.
    • Hemostasis: The entire process of stopping bleeding (vascular constriction, platelet plug, blood clot formation and clot dissolution).
    • Factors involved in blood coagulation: Various proteins and factors.

    Anticoagulants

    • Chemicals that prevent blood clots.
    • Physiological & therapeutic types, such as Vitamin K antagonists, direct oral anticoagulants (DOACs), and low-molecular-weight heparins (LMWHs).
    • Maintaining blood flow is crucial to prevent blockage

    Blood Disorders

    • Anemia: Low red blood cell count or reduced hemoglobin
    • Polycythemia: High red blood cell count

    Disorders of Haemostasis

    • Hypercoagulable disorders are where blood clots too easily.
    • Hypocoagulable disorders are where blood clots too slowly.
    • Bleeding disorders are where an individual cannot form blood clots effectively.

    Inflammation

    • Localized physical condition from injury.
    • Redness, swelling, heat, and pain are common signs.
    • Chemicals such as histamine, serotonin and bradykinin are involved.

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