Bleeding Disorders Integrated Hematology/Oncology Module

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Questions and Answers

Hemophilia A is characterized by deficiency of factor IX.

False (B)

Clinical manifestation of anti-phospholipid syndrome may include both transient ischemic stroke and blood in the urine.

False (B)

Plasmapheresis is a potential treatment option for controlling progressive thromboembolism in patients with Catastrophic Antiphospholipid Syndrome (CAPS).

True (A)

Pharmacists do not play a significant role in managing blood disorders.

<p>False (B)</p> Signup and view all the answers

Hemophilia B is characterized by deficiency of factor IX.

<p>True (A)</p> Signup and view all the answers

What is the direct cost of care related to hemophilia A in 2008?

<p>More than $140,000 (D)</p> Signup and view all the answers

In which type of bleeding disorder is there a congenital deficiency in a plasma coagulation protein?

<p>Hemophilia A (B)</p> Signup and view all the answers

What is the approximate number of males in the US affected by hemophilia A?

<p>30,000 (D)</p> Signup and view all the answers

Which organization has published 2021 guidelines on the management of von Willebrand disease?

<p>ASH (C)</p> Signup and view all the answers

What is a potential complication for patients with hemophilia A in terms of healthcare costs?

<p>Development of inhibitors (B)</p> Signup and view all the answers

What is the recommended treatment for antiphospholipid syndrome in adults according to EULAR?

<p>Anticoagulation therapy (B)</p> Signup and view all the answers

What is the inheritance pattern of Hemophilia B?

<p>X-linked recessive (B)</p> Signup and view all the answers

Which factor is deficient in Hemophilia A?

<p>Factor VIII (C)</p> Signup and view all the answers

What percentage of all patients with hemophilia have Hemophilia A?

<p>80-85% (B)</p> Signup and view all the answers

In terms of circulating factor levels, which category of hemophilia is defined as 'severe'?

<p>1 – 5% circulating factor (B)</p> Signup and view all the answers

Which of the following is a clinical manifestation of anti-phospholipid syndrome in a newly diagnosed patient?

<p>Transient ischemic stroke (B)</p> Signup and view all the answers

What is the primary treatment for controlling progressive thromboembolism in patients with Catastrophic Antiphospholipid Syndrome (CAPS)?

<p>Plasmapheresis (A)</p> Signup and view all the answers

What role do pharmacists play in managing blood disorders?

<p>Provide treatment recommendations and manage drug interactions (A)</p> Signup and view all the answers

Which blood disorder may require acute management and prophylaxis due to potential complications?

<p>Hemophilia (C)</p> Signup and view all the answers

How are DOACs (Direct Oral Anticoagulants) used in the context of typical VTE?

<p>For prophylaxis only (B)</p> Signup and view all the answers

What are the potential treatments for Catastrophic Antiphospholipid Syndrome (CAPS)?

<p>All of the above (D)</p> Signup and view all the answers

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