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Questions and Answers
Which symptom is commonly associated with primary haemostatic disorders?
Which symptom is commonly associated with primary haemostatic disorders?
- Epistaxes (correct)
- Intramuscular haematomas
- Prolonged bleeding time
- Haemarthroses
What is a distinguishing feature of secondary haemostatic disorders?
What is a distinguishing feature of secondary haemostatic disorders?
- Haemarthroses occurs commonly (correct)
- Bleeding is immediate
- Gender distribution is equal
- Petechiae are common
Which condition is characterized by a platelet count below 150 x 10^9/L?
Which condition is characterized by a platelet count below 150 x 10^9/L?
- Thrombocytopenia (correct)
- Leukopenia
- Thrombocytosis
- Normal platelet count
Which of the following is NOT a common symptom of primary haemostatic disorders?
Which of the following is NOT a common symptom of primary haemostatic disorders?
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In which gender is secondary haemostatic disorders more prevalent?
In which gender is secondary haemostatic disorders more prevalent?
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Study Notes
Primary Haemostatic Disorder
- Characterized by thrombocytopenia and von Willebrand disease (VWD).
- Immediate bleeding occurs upon injury.
- Common symptoms include:
- Petechiae: small, red or purple spots caused by bleeding under the skin.
- Epistaxis: frequent nosebleeds.
- Menorrhagia: heavy menstrual bleeding.
- Haemarthroses (joint bleeding) do not occur.
- Intramuscular hematomas are uncommon.
- Gender distribution is equal, affecting both sexes similarly.
Coagulation Disorder (Secondary Haemostatic Disorders)
- Primarily associated with hemophilia.
- Delayed bleeding occurs after injury.
- Symptoms vary:
- No petechiae present.
- Epistaxis is not commonly reported.
- Menorrhagia is not frequently observed.
- Haemarthroses occur commonly, leading to bleeding into joints.
- Intramuscular hematomas are a common finding.
- More than 80% of cases are found in males.
Causes of Bleeding Defects
- Vascular defects: weak vessels that leak blood.
- Decreased platelet number: condition known as thrombocytopenia.
- Decreased platelet function.
- Decreased coagulation factors in the blood.
Thrombocytes (Platelets)
- Also referred to as platelets, essential for blood clotting.
- Normal platelet count ranges from 150 to 400 x 10^9/L.
Thrombocytopenia
- Defined as a condition with a low platelet count, significantly below the normal range.
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