Bleeding Disorders in Pregnancy
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A pregnant woman at 26 weeks' gestation is diagnosed with gestational diabetes mellitus (GDM). Besides dietary changes, what is the MOST appropriate next step in managing her condition?

  • Prescribing oral hypoglycemic agents like metformin.
  • Monitoring blood glucose levels weekly without intervention unless symptoms worsen.
  • Initiating insulin therapy if glucose levels are not controlled with diet and exercise. (correct)
  • Recommending a high-protein, low-carbohydrate diet without exercise.

A patient at 34 weeks' gestation presents with a blood pressure of 160/110 mmHg and proteinuria. What is the MOST important immediate intervention to prevent potential complications?

  • Prescribing a diuretic to reduce fluid retention.
  • Administering a tocolytic to prevent preterm labor.
  • Encouraging bed rest and close outpatient monitoring.
  • Initiating magnesium sulfate to prevent seizures and controlling blood pressure. (correct)

Which of the following is the MOST critical initial step in managing a patient with hyperemesis gravidarum?

  • Providing reassurance and dietary advice.
  • Administering oral antiemetics.
  • Initiating intravenous fluids to correct dehydration and electrolyte imbalances. (correct)
  • Recommending small, frequent meals.

Twenty-four hours postpartum, a woman is experiencing excessive vaginal bleeding. The nurse has already massaged the uterus. Which intervention should be implemented NEXT?

<p>Administering a uterotonic medication, such as oxytocin or misoprostol. (D)</p> Signup and view all the answers

A postpartum patient reports fever, lower abdominal pain, and foul-smelling lochia. What condition is MOST likely, and what is the initial treatment?

<p>Endometritis; intravenous antibiotics. (C)</p> Signup and view all the answers

A woman who delivered vaginally 3 weeks ago reports persistent sadness, fatigue, and difficulty bonding with her baby. What is the MOST appropriate initial intervention?

<p>Screening for postpartum depression and providing information on therapy and support groups. (A)</p> Signup and view all the answers

Which of the following signs or symptoms in a postpartum woman should prompt immediate evaluation for a thromboembolic disorder?

<p>Localized calf pain, redness, and swelling in one leg. (A)</p> Signup and view all the answers

A patient who had a cesarean section five days ago presents with fever, increased pain, and purulent drainage from the incision site. What is the MOST appropriate next step in management?

<p>Initiating broad-spectrum antibiotics and providing local wound care. (A)</p> Signup and view all the answers

A pregnant woman with a known history of Von Willebrand disease (VWD) is in her third trimester. Which of the following management strategies is MOST appropriate to prepare for delivery and minimize the risk of postpartum hemorrhage (PPH)?

<p>Coordinate with a hematologist to optimize factor replacement therapy and monitor coagulation factors closely during labor and delivery. (B)</p> Signup and view all the answers

A couple with a family history of cystic fibrosis is seeking genetic counseling before planning a pregnancy. Both partners are of Caucasian descent. What is the MOST appropriate initial step in assessing their risk?

<p>Recommend carrier screening for cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations for both partners. (C)</p> Signup and view all the answers

A 38-year-old primigravida with a BMI of 35 is being managed for a high-risk pregnancy. She has no known pre-existing medical conditions but is at risk due to her age and BMI. What is the MOST important aspect of her prenatal care?

<p>Early screening for gestational diabetes and preeclampsia, along with regular monitoring for other complications. (B)</p> Signup and view all the answers

A 32-year-old pregnant woman is diagnosed with gestational thrombocytopenia at 30 weeks gestation. Her platelet count is 90,000/μL, and she is asymptomatic. Which of the following is the MOST appropriate next step in her management?

<p>Monitor platelet counts regularly and assess for signs of bleeding; avoid invasive procedures if possible. (A)</p> Signup and view all the answers

A couple who are both carriers for sickle cell trait are undergoing genetic counseling. What is the probability that their child will have sickle cell disease?

<p>25% (D)</p> Signup and view all the answers

A woman with a history of preeclampsia in a previous pregnancy is now in her second trimester. Which intervention is MOST effective in reducing her risk of recurrent preeclampsia?

<p>Prescribing low-dose aspirin (81 mg) daily starting at 12-16 weeks gestation. (C)</p> Signup and view all the answers

A patient at 39 weeks gestation is diagnosed with mild gestational hypertension. Which of the following is the MOST important factor to consider when determining the timing and method of delivery?

<p>The presence of any signs or symptoms indicative of preeclampsia or worsening hypertension. (D)</p> Signup and view all the answers

A woman experienced a severe postpartum hemorrhage (PPH) following the delivery of her previous child. She is now pregnant again. Which of the following is the MOST important step to prevent recurrence of PPH in this pregnancy?

<p>Develop a comprehensive plan for the active management of the third stage of labor, including uterotonic medications and controlled cord traction. (D)</p> Signup and view all the answers

Flashcards

Bleeding Disorders

Disorders that affect blood clotting processes, potentially leading to excessive bleeding.

Von Willebrand Disease (VWD)

A common bleeding disorder caused by a deficiency or defect in von Willebrand factor, affecting platelet adhesion.

Thrombocytopenia

A condition characterized by a low platelet count, increasing the risk of bleeding.

Genetic Counseling

A process to assess and communicate the risk of inherited conditions to families.

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Carrier Screening

Testing to identify individuals who carry a single copy of a gene for a recessive disorder.

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Prenatal Genetic Testing

Procedures used to obtain fetal cells for genetic testing.

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High-Risk Pregnancies

Pregnancies with increased risk of complications due to various factors.

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Gestational Conditions

Conditions that develop during pregnancy, such as gestational diabetes or preeclampsia.

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Gestational Diabetes Mellitus (GDM)

Glucose intolerance that develops during pregnancy.

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Preeclampsia

A hypertensive disorder of pregnancy with high blood pressure and proteinuria.

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Hyperemesis Gravidarum

Severe nausea and vomiting during pregnancy leading to dehydration.

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Postpartum Hemorrhage (PPH)

Excessive bleeding after delivery, a leading cause of maternal mortality.

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Endometritis

Infection of the uterine lining after childbirth.

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Mastitis

Breast infection after childbirth.

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Postpartum Depression (PPD)

Mood disorder affecting women after childbirth.

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Postpartum Thromboembolic Disorders

Blood clot disorders, like DVT, more common after giving birth.

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Study Notes

  • Care of mother and child at risk encompasses a wide spectrum of acute and chronic conditions, bleeding disorders, genetic predispositions, high-risk pregnancies, gestational conditions, and postpartum complications.

Bleeding Disorders in Pregnancy

  • Bleeding disorders during pregnancy can lead to significant maternal and fetal morbidity.
  • Common bleeding disorders include:
    • Von Willebrand disease (VWD)
    • Hemophilia (rare in females but possible)
    • Thrombocytopenia (low platelet count).
  • Thrombocytopenia can be gestational, immune-related (ITP), or due to other causes like HELLP syndrome.
  • Management involves careful monitoring of coagulation factors, platelet counts, and bleeding risk assessment.
  • Treatment options range from supportive care to factor replacement therapy or platelet transfusions, depending on the severity and cause.
  • Postpartum hemorrhage (PPH) is a major concern, and management strategies should be in place for women with bleeding disorders.

Genetic Counseling

  • Genetic counseling is crucial for families with a history of genetic disorders or those at risk of having a child with a genetic condition.
  • The process involves:
    • Assessing family history
    • Evaluating the risk of genetic disorders
    • Discussing available genetic testing options
    • Explaining the implications of test results.
  • Carrier screening can identify individuals who carry a gene for a recessive disorder, such as cystic fibrosis or sickle cell anemia.
  • Prenatal genetic testing options include:
    • Chorionic villus sampling (CVS)
    • Amniocentesis
    • Non-invasive prenatal testing (NIPT).
  • Genetic counseling helps families make informed decisions about family planning and prenatal care.

High-Risk Pregnancies

  • High-risk pregnancies involve factors that increase the likelihood of complications for the mother or fetus.
  • Risk factors include:
    • Advanced maternal age
    • Pre-existing medical conditions (diabetes, hypertension, heart disease)
    • Multiple gestation
    • History of pregnancy complications.
  • Management requires close monitoring, specialized care, and a multidisciplinary approach.
  • Prenatal care includes:
    • Frequent check-ups
    • Ultrasound monitoring
    • Screening for gestational diabetes and preeclampsia.
  • Delivery planning may involve induction of labor or cesarean delivery depending on the specific risks.

Gestational Conditions

  • Gestational conditions are those that arise during pregnancy.
  • Gestational diabetes mellitus (GDM) is a common condition characterized by glucose intolerance that develops during pregnancy.
  • Screening for GDM typically occurs between 24 and 28 weeks of gestation.
  • Management involves dietary modifications, exercise, and sometimes insulin therapy to maintain optimal glucose control.
  • Preeclampsia is a hypertensive disorder of pregnancy characterized by high blood pressure and proteinuria.
  • Severe preeclampsia can lead to serious complications such as:
    • Eclampsia (seizures)
    • HELLP syndrome (hemolysis, elevated liver enzymes, low platelet count).
  • Management includes:
    • Blood pressure control
    • Magnesium sulfate to prevent seizures
    • Delivery of the baby if the condition is severe or the pregnancy is near term.
  • Hyperemesis gravidarum is severe nausea and vomiting during pregnancy that can lead to dehydration and electrolyte imbalances.
  • Management involves:
    • Intravenous fluids
    • Antiemetic medications
    • Nutritional support.

Postpartum Complications

  • Postpartum complications can occur in the days and weeks following childbirth.
  • Postpartum hemorrhage (PPH) is excessive bleeding after delivery and is a leading cause of maternal mortality.
  • Risk factors include:
    • Uterine atony
    • Lacerations
    • Retained placental fragments
    • Coagulation disorders.
  • Management involves:
    • Uterotonic medications (oxytocin, misoprostol)
    • Uterine massage
    • Repair of lacerations
    • In severe cases, blood transfusions or surgery.
  • Postpartum infections can include:
    • Endometritis (infection of the uterine lining)
    • Wound infections
    • Mastitis (breast infection).
  • Treatment involves antibiotics and supportive care.
  • Postpartum depression (PPD) is a mood disorder that can affect women after childbirth.
  • Symptoms include:
    • Sadness
    • Fatigue
    • Anxiety
    • Difficulty bonding with the baby.
  • Treatment options include:
    • Therapy
    • Antidepressant medications
    • Support groups.
  • Thromboembolic disorders, such as deep vein thrombosis (DVT) and pulmonary embolism (PE), are more common in the postpartum period.
  • Management involves:
    • Anticoagulation therapy
    • Monitoring for signs of recurrence.
  • Wound complications following cesarean section, such as infection or dehiscence, require prompt management with antibiotics and wound care.

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Description

Overview of bleeding disorders during pregnancy, including Von Willebrand disease, hemophilia, and thrombocytopenia. Focus on management strategies, monitoring coagulation factors, and postpartum hemorrhage risks. Treatment options include supportive care, factor replacement therapy and platelet transfusions.

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