Biotechnology Introduction and History
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Questions and Answers

Which of the following are considered features of biotechnology products and processes?

  • healthcare and medicine
  • biofuels
  • environmental safety
  • all of the above (correct)

Biotechnology is a branch of applied science that utilizes only non-living organisms and their derivatives.

False (B)

Which of the following sciences does biotechnology interact and benefit from?

  • Biology
  • Microbiology
  • Biochemistry
  • Chemistry
  • Engineering
  • Mathematics
  • Computer Science
  • All of the above (correct)

In the ancient Egyptian civilization, what two products were produced using biotechnological methods?

<p>bread and beer</p> Signup and view all the answers

The term 'Anno Domini' (AD) is a secular term used to denote a time period?

<p>False (B)</p> Signup and view all the answers

What significant discovery did Edward Jenner make in 1796?

<p>Smallpox vaccine</p> Signup and view all the answers

Who was credited with discovering Chromosomes in 1902?

<p>Sutton</p> Signup and view all the answers

The term "______" was coined by Johannsen in 1909 to describe the fundamental unit of heredity.

<p>gene</p> Signup and view all the answers

What discovery was made by Watson and Crick in 1953?

<p>The structure of the double helix of DNA (D)</p> Signup and view all the answers

Modern biotechnology began around the start of the twentieth century.

<p>False (B)</p> Signup and view all the answers

The growing automobile industry started using fermentation processes in the early 20th century.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a key area where biotechnology is currently being used?

<p>Astronomy (G)</p> Signup and view all the answers

The human genome contains approximately 22,000 genes.

<p>True (A)</p> Signup and view all the answers

What is the name of the revolutionary gene editing technology that was used to treat cancer in 2020?

<p>CRISPR</p> Signup and view all the answers

Match the following colors of biotechnology with their corresponding fields:

<p>Blue Biotech = Aquatic and marine fields Green Biotech = Agriculture-related; production of biofertilizers and biopesticides Red Biotech = Healthcare; drugs, gene and cell therapies, antibodies and molecular diagnosis techniques Yellow Biotech = Food production Brown Biotech = Deserts and dry regions Golden Biotech = Bioinformatics, computational science and analysis of biological data Gray Biotech = Environment, protection, maintenance of biodiversity and removal of pollutants as bioremediation Purple Biotech = Laws, ethics and philosophy Black Biotech = Bioterrorism and biological warfare</p> Signup and view all the answers

What type of bioengineering research is essential for advancements in food security, biotechnology, and human nutrition?

<p>Microbial genome sequencing and bioengineering</p> Signup and view all the answers

Bioprocessing engineering encompasses both ______ engineering and ______ engineering.

<p>biochemical and biological</p> Signup and view all the answers

Which stage of bioprocess engineering involves the selection of organisms and media?

<p>Upstream processing (USP) (B)</p> Signup and view all the answers

Microorganisms used in bioprocesses should be pathogenic and hazardous.

<p>False (B)</p> Signup and view all the answers

What is the primary goal of downstream processing (DSP) in bioprocessing?

<p>The purification and packaging of the final product</p> Signup and view all the answers

Fermentation, a metabolic process, always results in the production of an alcohol.

<p>False (B)</p> Signup and view all the answers

Fermentation processes can occur only under anaerobic conditions.

<p>False (B)</p> Signup and view all the answers

Which of the following is a device employed to carry out fermentation processes on a large scale?

<p>Fermentor (A)</p> Signup and view all the answers

What are the two main outcomes of fermentation processes in relation to the desired product?

<p>increase and decrease</p> Signup and view all the answers

Fermented foods, like bread and beer, tend to retain less nutrition than their raw material counterparts.

<p>False (B)</p> Signup and view all the answers

Lactic acid-producing bacteria play a role in the production of yogurt and cheese.

<p>True (A)</p> Signup and view all the answers

The fermentation of tea leaves and coffee beans results in a reduction of their flavor.

<p>False (B)</p> Signup and view all the answers

How many stages are typically involved in the fermentation process?

<p>six</p> Signup and view all the answers

The sterilization step in fermentation is only necessary for the medium used.

<p>False (B)</p> Signup and view all the answers

The creation of optimum conditions in the fermentor ensures the growth of the desired organism and production of the target product.

<p>True (A)</p> Signup and view all the answers

What are the two alternate terms used to describe the fermentation process due to the interrelationships between microorganisms and the process?

<p>Biofermentor or Bioreactor</p> Signup and view all the answers

Which of the following are advantages of producing materials using fermentation?

<p>All of the above (F)</p> Signup and view all the answers

Fermentation products are typically produced in high concentrations, similar to chemically derived compounds.

<p>False (B)</p> Signup and view all the answers

Purification of fermentation products is a straightforward and inexpensive process.

<p>False (B)</p> Signup and view all the answers

Microbial processes are typically much faster than chemical processes.

<p>False (B)</p> Signup and view all the answers

Microbial contamination is a common concern during fermentation processes.

<p>True (A)</p> Signup and view all the answers

Microorganisms are highly tolerant of extreme variations in temperature and pH.

<p>False (B)</p> Signup and view all the answers

Waste products produced during fermentation are toxic and pose significant environmental risks.

<p>False (B)</p> Signup and view all the answers

Fermentation processes primarily rely on bacteria, fungi, and yeasts for production.

<p>True (A)</p> Signup and view all the answers

Which of the following is NOT a type of fermentation product?

<p>All of the above are fermentation products (G)</p> Signup and view all the answers

Primary metabolites are essential for the growth and development of organisms.

<p>True (A)</p> Signup and view all the answers

Secondary metabolites are produced only in stressful conditions for the organisms.

<p>False (B)</p> Signup and view all the answers

Which of the following is NOT an example of a secondary metabolite?

<p>Ethanol (B)</p> Signup and view all the answers

The regulation of biosynthesis for secondary metabolites is the same as for primary metabolites.

<p>False (B)</p> Signup and view all the answers

Secondary metabolite production is primarily associated with the trophophase.

<p>False (B)</p> Signup and view all the answers

The trophophase and idiophase are always clearly separated in all fermentation processes.

<p>False (B)</p> Signup and view all the answers

Biocatalysis is a process that aims to optimize fermentation conditions to improve yield, quality, and purity of the final product.

<p>True (A)</p> Signup and view all the answers

Biocatalysis can only involve the use of whole organisms, never individual components.

<p>False (B)</p> Signup and view all the answers

Biocatalysts for reduction reactions can be found only in microbes.

<p>False (B)</p> Signup and view all the answers

Whole cell biocatalysts can utilize the presence of respiratory chains to achieve specific reactions.

<p>True (A)</p> Signup and view all the answers

Lipase is a type of enzyme used in washing powders for the removal of fat stains.

<p>True (A)</p> Signup and view all the answers

Which of these is an example of a process that could be achieved using whole-cell biocatalysis?

<p>Production of ethanol from sugar (A)</p> Signup and view all the answers

Flashcards

Biotechnology

The application of living organisms or their derivatives to create useful products or processes.

Biotechnology Applications

Biotechnology's use in areas like healthcare, biofuels, and environmental cleanup.

Ancient Biotechnology Example

Ancient civilizations used biotechnology for bread and beer production.

Modern Biotechnology Start

Modern biotechnology began roughly around the end of the 19th century.

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Mendel's Work

Mendel's genetics work was crucial in the development of modern biotechnology.

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Microbial Processes Studies

Scientists like Koch, Pasteur, and Lister investigated fermentation and other microbial processes.

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Early 20th Century Biotechnology

Industry and agriculture started using biotechnology in the early 20th century.

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DNA Structure Discovery

Watson and Crick's discovery of DNA's double helix structure was a major step forward

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DNA Manipulation Techniques

Techniques for manipulating DNA emerged in the mid-20th century enabling genetic engineering.

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Genetically Engineered Products

Products like insulin were among the first ones genetically engineered.

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Human Genome Project

Identifying the entire sequence of human DNA—a huge undertaking that advanced biotechnology.

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Blue Biotech

Biotechnology related to aquatic and marine environments and organisms.

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Green Biotech

Biotechnology related to agricultural practices.

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Red Biotech

Biotechnology focused on healthcare applications.

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Yellow Biotech

Biotechnology related to food production.

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Brown Biotech

Biotechnology related to arid and semi-arid regions.

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Golden Biotech

Biotechnology involving bioinformatics and biological data analysis.

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Gray Biotech

Biotechnology related to environmental protection and bioremediation

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White Biotech

Biotechnology dealing with Industrial processes and enzyme use.

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Purple Biotech

Biotechnology involving laws, ethics and the philosophy behind usage.

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Black Biotech

Biotechnology dealing with bioweapons and bioterrorism.

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Microbial Biotechnology

Biotechnology applying microorganisms to create products and processes.

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Bioprocessing Engineering

Engineering specialty applying biological or biochemical processes for products.

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Fermentation

Metabolic process where organisms convert carbohydrates into alcohol or acids.

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Fermentor

Device for large-scale fermentation.

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Study Notes

Biotechnology Introduction

  • Biotechnology is a branch of applied science using living organisms and their derivatives to produce or modify products and processes.
  • Applications include healthcare, medicine, biofuels, and environmental safety.
  • Biotechnology interacts with various sciences, including biology, microbiology, biochemistry, chemistry, engineering, mathematics, and computer science.

History of Biotechnology

  • Ancient Egyptians used biotechnological processes for bread and beer production, depicted in their temples.
  • Key historical milestones include the use of yeast for fermentation (6000 BCE), the development of vaccines, and the understanding of genetics.
  • Modern biotechnology emerged in the late 19th and early 20th centuries with developments in genetics, fermentation, and microbial processes.

Modern Biotechnology

  • Modern biotechnology started at the end of the 19th century, with Mendel's work, and the development of Koch, Pasteur, and Lister's institutes for investigating fermentation and microbial processes.
  • Advancements in the 20th century included the discovery of DNA structure by Watson and Crick, genetic engineering techniques, and the study of the human genome.
  • Today, biotechnology is widely used in agriculture, medicine, industry, and environmental applications.

Microorganisms in Biotechnology

  • Microbial growth and development are crucial to biotechnology.
  • Advancing diagnostic tools, biocontrol agents, and bioremediation are important applications of microbes in biotechnology.
  • Microbial genome sequencing and bioengineering contribute to food security, value-added products, and agricultural improvements.

Bioprocessing Engineering

  • Bioprocess engineering combines biochemical and biological engineering principles to efficiently produce desired biological materials.
  • Bioprocesses are categorized into upstream and downstream stages.
  • Upstream processing (USP) involves selecting an organism, sterilizing the growth medium, and establishing the inoculation conditions.
  • Downstream processing (DSP) focuses on product separation, purification, and formulation for packaging.

Fermentation Process

  • Fermentation is a metabolic process where organisms convert carbohydrates to alcohols or acids.
  • It was initially associated with anaerobic microbial cultivation.
  • Fermentation can now be aerobic or anaerobic using fresh or treated media, often using inert gases.
  • Fermentation yields numerous products like amino acids, enzymes, organic acids, and vitamins.
  • A fermentor is a device utilized for large-scale fermentation processes.

Advantages and Drawbacks of Fermentation

  • Fermentation offers advantages by producing complex molecules, optically active compounds, and by using renewable feed stocks.
  • Reaction conditions during fermentation are mild and can occur in a single vessel.
  • Drawbacks include low concentrations of products in complex solutions, product purification difficulties, slow processes, and microbial contamination susceptibility.

Cellular Processes in Fermentation

  • Primary metabolites, such as ethanol, lactic acid, and glycerol, are essential for energy storage and growth.
  • Secondary metabolites, such as antibiotics and vitamins, are usually needed for reproduction under specific conditions.
  • Various cellular activities contribute to the fermentation process, including metabolic pathways and biosynthesis of different molecules.

Biocatalysis

  • Biocatalysis leverages enzymes and whole cells for optimization of fermentation processes, improving reaction yield, purity, and quality.
  • Enzymes, such as lipases, which catalyze the reaction of alcohol and acids, are utilized for production.
  • Whole cell catalysts utilize the entire cell, rather than extracting and purifying specific enzymes.

Other Information

  • Production of tea, coffee, pickles, and other vegetables often rely on or benefit from fermentation processes to preserve flavor, enhance taste, and extend shelf life..

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Explore the fascinating world of biotechnology, from its roots in ancient practices to modern applications in medicine and environmental safety. This quiz covers key historical milestones, influential figures, and the interdisciplinary nature of biotechnology. Test your knowledge and understanding of this vital field!

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