Biosynthesis of Secondary Metabolites Quiz
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Questions and Answers

Which of the following compounds is NOT an intermediate in the biosynthetic pathways of secondary metabolites?

  • Shikimic acid
  • Glucose (correct)
  • Acetyl CoA
  • Malonic acid
  • What is the primary role of the shikimic acid pathway?

  • Production of alkaloids through glycolysis
  • Biosynthesis of aromatic amino acids and phenolic compounds (correct)
  • Degradation of primary metabolites
  • Biosynthesis of fatty acids
  • Which of the following is NOT a trigger for the expression of secondary metabolites in plants?

  • Environmental stress from herbivores
  • Altered pH levels
  • Increased photosynthetic rate (correct)
  • UV radiation
  • Which starting substrates are involved in the shikimic acid pathway?

    <p>Erythrose-4-phosphate and phosphoenol pyruvate</p> Signup and view all the answers

    Which aromatic amino acids are synthesized through the shikimic acid pathway?

    <p>Phenylalanine, tyrosine, and tryptophan</p> Signup and view all the answers

    What type of metabolites are primarily produced by the biosynthetic pathways discussed?

    <p>Secondary metabolites</p> Signup and view all the answers

    Which of the following is NOT a common environmental stress affecting secondary metabolite production?

    <p>Excessive nutrient availability</p> Signup and view all the answers

    Which class of organisms is capable of utilizing the shikimic acid pathway for biosynthesis?

    <p>Bacteria, fungi, algae, and some protozoans</p> Signup and view all the answers

    What is the role of DAHP synthase in the shikimate pathway?

    <p>It catalyzes the formation of 3-deoxy-D-arabino-heptulosonate 7-phosphate.</p> Signup and view all the answers

    Which compound is directly modified to contribute to the fatty acid synthesis in the acetate pathway?

    <p>Acetyl-CoA</p> Signup and view all the answers

    Which enzyme is associated with the transformation of 5-enolpyruvylshikimate-3-phosphate to chorismate?

    <p>Chorismate synthase</p> Signup and view all the answers

    What is the primary product of the mevalonate pathway?

    <p>Cholesterol</p> Signup and view all the answers

    Which of the following correctly describes the formation process of malonyl-CoA?

    <p>It results from the carboxylation of acetyl-CoA utilizing biotin.</p> Signup and view all the answers

    Which compounds are the initial building blocks derived from the mevalonate pathway?

    <p>Geranyl pyrophosphate and dimethylallyl pyrophosphate</p> Signup and view all the answers

    What type of metabolism is primarily connected by the shikimate pathway?

    <p>Aromatic amino acid synthesis</p> Signup and view all the answers

    Which of the following fatty acids can be directly synthesized from the acetate-malonate pathway?

    <p>All of the above</p> Signup and view all the answers

    What is the primary function of farnesyl pyrophosphate in the mevalonate pathway?

    <p>To facilitate cholesterol formation</p> Signup and view all the answers

    What kind of enzyme is shikimate kinase and what is its function?

    <p>An ATP-dependent enzyme that phosphorylates shikimate.</p> Signup and view all the answers

    Study Notes

    Biosynthesis of Secondary Metabolites

    • Biosynthesis is a multi-step process where simple compounds are converted into more complex products through enzyme-catalyzed reactions.
    • Primary metabolites are building blocks for biosynthesis, derived from photosynthesis, glycolysis, and the Krebs cycle.
    • Secondary metabolites are produced from primary metabolites and play a vital role in plant defense against environmental stresses like pathogens, herbivores, and UV radiation.

    Shikimic Acid Pathway

    • The Shikimic acid pathway is a seven-step pathway used by bacteria, archaea, fungi, algae, plants, and some protozoans for the biosynthesis of aromatic amino acids (phenylalanine, tyrosine, tryptophan) and folates.
    • Chorismate is the final product of the pathway and a precursor for the three aromatic amino acids.
    • Phenylpropanoid precursors are produced through the shikimic acid pathway, and they are abundant in plants, acting as a defense mechanism against environmental stresses.
    • This pathway is also known as the chorismate pathway.

    Malonic-Acid (Malonate/Acetate) Pathway

    • The acetate pathway involves acyl carrier protein (ACP) to yield fatty acylthioesters of ACP, which are important intermediates in fatty acid synthesis.
    • The pathway utilizes acetyl-CoA units to produce even-numbered fatty acids.
    • Malonyl-CoA is formed from acetyl-CoA by the addition of CO2, serving as the substrate for fatty acid synthase.

    Mevalonic-Acid (Mevalonate) Pathway

    • The mevalonic acid (MVA) pathway or isoprenoid pathway involves the synthesis of 3-hydroxy-3- methylglutaryl-CoA reductase (HMGCR).
    • The pathway is crucial for cholesterol biosynthesis and protein production in eukaryotic, archaea, and some bacteria organisms.
    • Isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) are the main intermediates of the MVA pathway, serving as building blocks for isoprenoid compounds.
    • Squalene is produced from farnesyl pyrophosphate and its cyclization leads to cholesterol and other triterpenoids.

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    Description

    Test your knowledge on the biosynthesis of secondary metabolites, including the shikimic acid pathway and its role in producing aromatic amino acids. Learn how these processes contribute to plant defense mechanisms against environmental stresses. This quiz covers essential concepts relating to primary and secondary metabolites.

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