Podcast
Questions and Answers
What is the immediate precursor of the predominant type of human prostaglandins (series 2)?
What is the immediate precursor of the predominant type of human prostaglandins (series 2)?
- Thromboxanes
- Linoleic acid
- Arachidonic acid (correct)
- Lipoxygenase pathway
Where is arachidonic acid typically incorporated in membrane phospholipids before being released by phospholipase A2?
Where is arachidonic acid typically incorporated in membrane phospholipids before being released by phospholipase A2?
- C-2 (correct)
- C-6
- C-10
- C-8
Which enzyme catalyzes the oxidative cyclization of free arachidonic acid to yield PGH2?
Which enzyme catalyzes the oxidative cyclization of free arachidonic acid to yield PGH2?
- Phospholipase A2
- Peroxidase
- Cyclooxygenase (correct)
- Lipoxygenase
What is a key difference between eicosanoids and endocrine hormones?
What is a key difference between eicosanoids and endocrine hormones?
What happens to eicosanoids after they are produced?
What happens to eicosanoids after they are produced?
Which statement accurately describes the role of eicosanoids?
Which statement accurately describes the role of eicosanoids?
Which enzyme converts arachidonic acid to 5-hydroperoxy-6,8,11,14 eicosatetraenoic acid?
Which enzyme converts arachidonic acid to 5-hydroperoxy-6,8,11,14 eicosatetraenoic acid?
Which eicosanoid has a major effect of vasodilatation and inhibits platelet aggregation?
Which eicosanoid has a major effect of vasodilatation and inhibits platelet aggregation?
Which type of cells lack nuclei and therefore cannot overcome COX-1 inhibition?
Which type of cells lack nuclei and therefore cannot overcome COX-1 inhibition?
What is the main prostaglandin produced by platelets that promotes thrombus formation?
What is the main prostaglandin produced by platelets that promotes thrombus formation?
