Podcast
Questions and Answers
What characterizes a microorganism in Risk Group 1?
What characterizes a microorganism in Risk Group 1?
- It usually causes serious disease and spreads easily.
- It poses a high risk to laboratory workers.
- It is unlikely to cause human or animal disease. (correct)
- It can cause serious disease but has effective treatment.
What defines a microorganism in Risk Group 4?
What defines a microorganism in Risk Group 4?
- Moderate individual risk and effective treatments available.
- Low risk of causing disease in humans or animals.
- High individual risk with limited community transmission.
- Highly communicable with serious disease and limited treatment options. (correct)
What is a characteristic of microorganisms categorized as Risk Group 3?
What is a characteristic of microorganisms categorized as Risk Group 3?
- They pose a low individual and community risk.
- They can easily be transmitted from one individual to another.
- They have effective treatment and preventive measures. (correct)
- They usually do not cause serious diseases in humans.
Which statement about Risk Group 2 is true?
Which statement about Risk Group 2 is true?
Which risk group includes pathogens that usually cause serious disease but do not readily spread between individuals?
Which risk group includes pathogens that usually cause serious disease but do not readily spread between individuals?
What is the main purpose of the Cartagena Protocol on Biosafety (CPB)?
What is the main purpose of the Cartagena Protocol on Biosafety (CPB)?
Which entity established the National Biosafety Framework (NBF) in the Philippines?
Which entity established the National Biosafety Framework (NBF) in the Philippines?
What was established under Executive Order 430 series of 1990?
What was established under Executive Order 430 series of 1990?
Which organization was founded as a response to the need for guidance in biosafety in North America?
Which organization was founded as a response to the need for guidance in biosafety in North America?
Which countries are members of the Asia-Pacific Biosafety Association?
Which countries are members of the Asia-Pacific Biosafety Association?
What does the Administrative Order No. 8 from the Department of Agriculture address?
What does the Administrative Order No. 8 from the Department of Agriculture address?
In what year was the European Biological Safety Association founded?
In what year was the European Biological Safety Association founded?
What is one of the main functions of the National Committee on Biosafety of the Philippines (NCBP)?
What is one of the main functions of the National Committee on Biosafety of the Philippines (NCBP)?
What role do BIOSAFETY OFFICERS play in a laboratory?
What role do BIOSAFETY OFFICERS play in a laboratory?
Which event in 2001 influenced laboratory biosecurity regulations in the US?
Which event in 2001 influenced laboratory biosecurity regulations in the US?
What is a focus of the CEN Workshop Agreement 15793 published in 2008?
What is a focus of the CEN Workshop Agreement 15793 published in 2008?
In the context of biosafety, what do Biosafety Levels indicate?
In the context of biosafety, what do Biosafety Levels indicate?
Who is considered a pioneer in the field of biosafety along with Arnold Wedum?
Who is considered a pioneer in the field of biosafety along with Arnold Wedum?
What was a significant change made in the 2012 revision of the SELECT AGENT REGULATIONS?
What was a significant change made in the 2012 revision of the SELECT AGENT REGULATIONS?
What is the purpose of the WHO's Laboratory Biosafety Manual published in 1983?
What is the purpose of the WHO's Laboratory Biosafety Manual published in 1983?
Which type of anthrax is considered the most serious form?
Which type of anthrax is considered the most serious form?
What is the primary purpose of personal protective equipment (PPE)?
What is the primary purpose of personal protective equipment (PPE)?
What does the term 'donning' refer to in the context of PPE?
What does the term 'donning' refer to in the context of PPE?
Which of the following is NOT a function of gloves as PPE?
Which of the following is NOT a function of gloves as PPE?
Which biosafety level (BSL) indicates laboratories that study infectious agents not known to cause disease in healthy adults?
Which biosafety level (BSL) indicates laboratories that study infectious agents not known to cause disease in healthy adults?
What does doffing involve in the context of PPE usage?
What does doffing involve in the context of PPE usage?
What is the role of goggles as a type of PPE?
What is the role of goggles as a type of PPE?
Which biosafety level requires more advanced containment measures and is associated with working with agents that may cause serious disease?
Which biosafety level requires more advanced containment measures and is associated with working with agents that may cause serious disease?
Which of the following statements about PPE is true?
Which of the following statements about PPE is true?
What is the primary purpose of a Class I Biological Safety Cabinet?
What is the primary purpose of a Class I Biological Safety Cabinet?
Which class of Biological Safety Cabinet provides both personnel and product protection?
Which class of Biological Safety Cabinet provides both personnel and product protection?
What is a characteristic feature of Class III Biological Safety Cabinets?
What is a characteristic feature of Class III Biological Safety Cabinets?
Which of the following statements about Class II BSCs is true?
Which of the following statements about Class II BSCs is true?
What safety procedure is required before personnel can exit a BSL-4 laboratory?
What safety procedure is required before personnel can exit a BSL-4 laboratory?
In what way does a Class I BSC protect laboratory personnel?
In what way does a Class I BSC protect laboratory personnel?
What is NOT a function of Biological Safety Cabinets?
What is NOT a function of Biological Safety Cabinets?
Which type of Biological Safety Cabinet is specifically designed for handling radioisotopes and toxic chemicals?
Which type of Biological Safety Cabinet is specifically designed for handling radioisotopes and toxic chemicals?
Study Notes
Biosafety for Laboratories
- Biosafety Officers ensure proper equipment and facility controls based on laboratory's biosafety level.
- Arnold Wedum, US Army Biological Research Laboratories Director (1944), is considered a pioneer of biosafety.
- Morton Reitman, with Wedum, analyzed epidemiological studies of laboratory outbreaks in 1966.
- Select Agent Regulations (1996) monitor transfer of biological agents between facilities.
- The Cartagena Protocol on Biosafety (2003) provides an international framework for safe transfer, handling, and use of living modified organisms.
- National Biosafety Framework (2006, Philippines) strengthens the National Committee on Biosafety.
- National Committee on Biosafety of the Philippines (NCBP)(1990) focuses on biosafety organization structure.
- Department of Agriculture (DA) (Philippines) covers policies on import and release of bioengineered plants and products.
- Department of Health (DOH) (Philippines) works with NCBP to assess health impacts of biotechnology.
- American Biological Safety Association (1984) promotes biosafety as a scientific discipline, focusing on North America.
- Asia-Pacific Biosafety Association (2005) is a professional society for biosafety professionals in the Asia-Pacific region.
- European Biological Safety Association (1996) is a non-profit organization that includes members from various countries.
- Risk Group 1 - microorganisms unlikely to cause disease in healthy adults.
- Risk Group 2 - pathogens causing disease, but with effective treatment and limited risk of spread.
- Risk Group 3 - pathogens causing serious disease, not usually spread from person to person.
- Risk Group 4 - pathogens causing serious disease and easily transmissible, with limited treatment options.
Biosafety Levels (BSL)
- BSL-1 - basic safety practices, no special equipment needed.
- BSL-2 - working with moderate individual risk and low community risk.
- BSL-3 - working with high individual risk and low community risk.
- BSL-4 - working with high individual and community risk, requiring specialized facilities and protocols.
Containment
- Containment protects personnel, work environment, and the community from biological agents.
- Bio-containment refers to the same protective measures.
PPE
- Personal Protective Equipment (PPE) is the last line of defense against hazards.
- Donning is the proper putting on and use of PPE.
- Doffing is the safe removal of PPE to prevent self-contamination.
Biological Safety Cabinets (BSCs)
- BSCs are enclosed ventilated workspaces offering primary containment.
- Class I BSCs provide operator and environmental protection, but not product protection.
- Class II BSCs Provide operator, environmental, and product protection, recirculating a portion of air back into the work area.
- Class III BSCs Offer maximum protection with a sealed, negative-pressure enclosure, requiring specialized gloves for access.
Suit Laboratories
- Suit Laboratories require personnel to wear full-body, air-supplied suits for maximum protection.
Microorganism Classifications
- Virulence and pathogenicity - ability of an organism to cause disease
- Infectious dose - minimum dose required to cause infection
- Environmental stability - ability to survive outside the host
- Route/s of exposure - ways an organism enters the body
- Communicability - ease of transmission between individuals
- Quantity concentration - amount of organism present
- Availability of vaccine or treatment - availability of prevention or cure
- Gene product effects - effects of the organism's genetic products
- Origin of agent - origin of the organism
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Description
Explore the essential concepts of biosafety in laboratory settings. This quiz covers historical figures, regulations, and international frameworks related to biosafety, including notable protocols and national frameworks. Test your knowledge on the safety practices that safeguard public health and the environment.
