BIOS252 Week 1 & 2 Review: Levers and Muscle Physiology
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Questions and Answers

What lever class has the fulcrum situated between the force and the load?

  • First-class lever (correct)
  • Compound lever
  • Second-class lever
  • Third-class lever
  • Which element is important in directly triggering contraction?

    Calcium (Ca++)

    Identify the muscle that has the arrow pointing to it.

    Diaphragm muscle

    Thin and thick filaments are organized into functional units called ________.

    <p>Sarcomeres</p> Signup and view all the answers

    Cardiac muscles differ from skeletal muscles in that they contain ________.

    <p>intercalated discs</p> Signup and view all the answers

    Which connective tissue surrounds the entire muscle and separates it from surrounding tissues?

    <p>Epimysium</p> Signup and view all the answers

    What are the types of striated muscle?

    <p>Skeletal and cardiac muscles</p> Signup and view all the answers

    Which types of muscle are involuntary?

    <p>Cardiac and smooth muscles</p> Signup and view all the answers

    Smooth muscle is responsible for what movements?

    <p>moving the contents in the small intestine</p> Signup and view all the answers

    A ring-like band of muscle made of smooth muscle that will stop the flow of contents from one organ to another is known as what?

    <p>Sphincter</p> Signup and view all the answers

    How do muscles help control glucose levels in the bloodstream?

    <p>absorbing, storing, and using large amounts of glycogen</p> Signup and view all the answers

    What does excitability of the muscles mean?

    <p>the cell's ability to respond to stimuli</p> Signup and view all the answers

    Which function of muscle is best described as helping to maintain posture and preventing unwanted movements?

    <p>Stabilizing body positions</p> Signup and view all the answers

    Muscles have the ability to shorten. This is known as?

    <p>Contractility</p> Signup and view all the answers

    Is the return to an original shape after being stretched known as?

    <p>Elasticity</p> Signup and view all the answers

    Is the ability to stretch without tearing known as?

    <p>Extensibility</p> Signup and view all the answers

    Aerobic respiration is the type of energy creation that will give the muscle about two minutes of energy only.

    <p>False</p> Signup and view all the answers

    Between skeletal muscle, cardiac muscle, and smooth muscle, the smooth muscle has the lowest adenosine triphosphate (ATP) demands due to the latch-bridge mechanism.

    <p>True</p> Signup and view all the answers

    Which of the following is a function of smooth muscle?

    <p>Moving food through the digestive system</p> Signup and view all the answers

    What is the function of cardiac muscle?

    <p>pumping of blood in the heart</p> Signup and view all the answers

    Only __________ muscles are under __________ control, such as blinking your eyes.

    <p>Skeletal; voluntary</p> Signup and view all the answers

    The neurotransmitter used at the neuromuscular junction is?

    <p>Acetylcholine (ACh)</p> Signup and view all the answers

    Skeletal muscle fiber is considered to be multinucleated.

    <p>True</p> Signup and view all the answers

    What is the fixed point of a lever system that the movement is applied to known as?

    <p>Fulcrum</p> Signup and view all the answers

    What is the functional contractile unit of the myofibril where muscle tension is produced?

    <p>Sarcomere</p> Signup and view all the answers

    The connection formed between actin and myosin is known as what?

    <p>Cross-bridge</p> Signup and view all the answers

    Which regulatory protein binds calcium to initiate muscle contraction?

    <p>Troponin</p> Signup and view all the answers

    Titin sits between the M-line and Z-lines of the sarcomere and acts as a spring for actin filaments, attaching to the Z-line.

    <p>True</p> Signup and view all the answers

    During muscle contraction, the sarcomere shortens and the H-zone grows in size.

    <p>False</p> Signup and view all the answers

    What are the main contractile proteins of the thick and thin filaments in a sarcomere called?

    <p>Actin and Myosin</p> Signup and view all the answers

    Which layer of connective tissue surrounds each muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What happens to the I-band when the sarcomere contracts?

    <p>The I-bands shorten during contraction</p> Signup and view all the answers

    The two contractile proteins, actin and myosin, are the main myofilaments that form the sarcomere.

    <p>True</p> Signup and view all the answers

    Study Notes

    Muscle Types and Function

    • First-Class Lever: Fulcrum positioned between the force and load.
    • Agonist Support: Synergist muscles assist agonists in movement.
    • Prime Mover for Head Flexion: Sternocleidomastoid muscle is responsible.
    • Diaphragm Muscle: Primary muscle involved in respiration.

    Muscle Contraction Mechanism

    • Calcium (Ca++): Essential element for triggering muscle contraction.
    • Sarcomeres: Functional units comprised of thin and thick filaments.
    • Intercalated Discs: Unique feature of cardiac muscles not present in skeletal muscles.
    • Muscle Surrounding Tissue: Epimysium encases entire muscle and separates it from adjacent tissues.
    • Striated Muscle Types: Includes skeletal and cardiac muscles.

    Muscle Control and Characteristics

    • Involuntary Muscles: Cardiac and smooth muscles; operate without conscious control.
    • Smooth Muscle Function: Moves contents through organs like the small intestine.
    • Sphincter Muscles: Control flow between organs by contracting to close passageways.
    • Muscle Extensibility: Ability to stretch without injury.
    • Muscle Glycogen Utilization: Skeletal muscles manage glucose levels by storing glycogen.

    Muscle Properties

    • Excitability: Muscle cells create electrical currents through ion uptake.
    • Stabilization: Muscle contractility helps maintain posture.
    • Elasticity: Muscles return to original shape post-extension.
    • Electrical Excitability: Changes in resting membrane potential due to ion exchange.

    Muscle Fiber Organization

    • Types of Muscle Fiber: Skeletal fibers are long, thin, multinucleated, and voluntary.
    • Cardiac Muscle: Found strictly in the heart, has intercalated discs for synchronized contractions.
    • Smooth Muscle in Blood Vessels: Regulates blood flow and pressure.

    Contraction Terms and Mechanisms

    • Peristalsis: Smooth muscle contraction for food movement in the digestive tract.
    • Cross-Bridge Formation: Interaction between actin and myosin during contraction.
    • AChE (Acetylcholine Esterase): Enzyme that breaks down ACh at the neuromuscular junction.
    • Tetanus: Continuous muscle contraction due to high-frequency stimulation.

    Naming Skeletal Muscles

    • Muscle Naming Conventions: Based on location, size, shape, action, and number of origins.
    • Agonist: Main muscle responsible for a particular movement.
    • Muscle Attachment Points: Origin is fixed points, while insertion is the movable end.

    Muscle Actions and Synergists

    • Major and Minor Muscles: "Major" indicates the largest and most active muscle in a pair.
    • Skeletal Muscle actions: Includes movements like extending the forearm (triceps brachii) and flexing the vertebral column (rectus abdominis).
    • Synergists in Muscle Action: Support the primary mover during contractions (e.g., pectoralis major for arm movements).

    Muscle Disorders and Function

    • Myasthenia Gravis: Autoimmune disorder disrupting neuromuscular transmission leading to muscle weakness.
    • Duchenne Muscular Dystrophy: Genetic disorder resulting in muscle tissue degeneration and replacement with fat.

    Energy and Muscle Maintenance

    • ATP Production: Muscle fibers predominantly utilize aerobic respiration for sustained energy.
    • Thermoregulation: Muscle contractions produce heat as by-products of ATP production during physical activity.
    • Latch-Bridge Mechanism: Allows smooth muscle to sustain contractions with minimal energy usage.

    Muscle Structure Insights

    • Sarcomere Structure: Actin and myosin overlap within the A-band, while I-bands shorten during contraction.
    • Calcium's Role: Initiates muscle contraction by binding to troponin, causing tropomyosin shifts to expose actin binding sites.
    • Connective Tissue: Endomysium surrounds each muscle fiber, while Z-line defines the boundaries of each sarcomere.### Muscle Contraction and Sarcomere Structure
    • Actin and myosin are the primary contractile proteins that form the sarcomere.
    • Hydrolysis of ATP does not cause conformational changes in the head region of actin.
    • Troponin and tropomyosin are regulatory proteins associated with actin and myosin.
    • Myomesin serves as the structural protein in the M-line of the sarcomere.
    • Titin acts as a spring for actin filaments, connecting to the Z-line and providing elastic properties.
    • During muscle contraction, the sarcomere shortens, and the H-zone does not increase in size; it actually decreases.

    Nervous System Structure

    • Neurons are the fundamental units of the nervous system responsible for information transmission and processing.
    • Dendrites are branch-like extensions that receive signals from other neurons or sensory receptors.
    • Axons are the main output structures transmitting electrical signals away from the neuron's cell body.
    • Synapses are specialized junctions for communication between neurons or with target cells.

    Myelin Sheath

    • The myelin sheath is produced by Schwann cells in the peripheral nervous system and oligodendrocytes in the central nervous system.

    Action Potentials and Ion Channels

    • Voltage-gated channels open in response to changes in membrane potential, generating action potentials.
    • Saltatory conduction, occurring along myelinated axons, enhances the speed of action potentials.

    Organization of the Nervous System

    • The nervous system consists of two main divisions: Central Nervous System (CNS) and Peripheral Nervous System (PNS).
    • Integration of postsynaptic potentials from multiple presynaptic neurons characterizes spatial summation.

    Additional Neuroglial Functions

    • Astrocytes are crucial for maintaining the blood-brain barrier and regulating the extracellular environment of neurons.
    • Graded potentials refer to small, localized changes in membrane potential that vary in amplitude.

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    Review of BIOS252 week 1 and 2 covering levers, agonist, synergist, and prime movers in head flexion. Test your knowledge with this quiz!

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