Questions and Answers
What is the focus of a biosafety risk assessment?
What is the formula for calculating likelihood in a biosecurity risk assessment?
Likelihood = [(motive + capability + historical frequency (proximity + distance)]/4
Risk is calculated as Likelihood multiplied by __________.
Consequences
Biosafety practices and biosecurity systems are completely unrelated.
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Which of the following are common components of biosafety and biosecurity?
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Biosafety and biosecurity can sometimes have conflicting measures.
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Match the following aspects of biosafety and biosecurity:
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The best strategy for an effective continual improvement program is:
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What steps regarding the equipment decontamination should maintenance engineers take?
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What does likelihood refer to in the context of a laboratory incident?
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What is consequence in relation to a laboratory incident?
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What is needed to develop a biorisk management system?
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When should a laboratory perform an initial risk assessment?
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What does the Matrix Method primarily help identify?
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What is one disadvantage of the Matrix Method?
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What is the first step in implementing the BRM system in a new organization?
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Study Notes
Biorisk Management System (BRM) Overview
- BRM emphasizes continual improvement using the PDCA (Plan-Do-Check-Act) cycle.
- Shorter PDCA cycles enhance effectiveness in continual improvement programs.
Decontamination Responsibilities
- Maintenance engineers should confirm equipment decontamination with laboratory staff before proceeding with maintenance.
- Engineers must not assume responsibility lies solely with lab workers, nor should they ignore decontamination.
Understanding Biorisk
- Biological materials pose varying levels of risk; a proper biorisk management system mitigates these risks.
- Risk assessments must consider specific conditions unique to each laboratory setting.
Variability in Risks
- Risk factors include:
- Equipment condition,
- Facility state,
- Biological agent's community prevalence,
- Local population susceptibility,
- Personnel competency.
Biorisk Assessment
- Conduct biorisk assessments to inform risk management strategies based on likelihood and consequences of incidents.
- A biorisk assessment team should include principal investigators, lab managers, technicians, and biosafety officers.
Timing for Assessments
- Initial risk assessments should occur before any laboratory work begins, with subsequent assessments needed during:
- Equipment or facility changes,
- Regulatory updates,
- Personnel changes,
- New biological agents.
Gathering Risk Information
- Focus areas for information gathering include:
- Biological agents' pathogenic characteristics,
- Laboratory procedures and equipment,
- Facility specifics and human factors affecting operations.
Risk Evaluation
- Assess risks using Likelihood x Consequence = Risk.
- Likelihood ratings range from "rare" (1) to "almost certain" (5) based on incident probabilities.
- Consequence assessments categorize incidents from "negligible" to "severe" based on health and environmental impacts.
Risk Control Strategy Development
- Identify available resources for implementing risk control measures.
- Control measures must be effective, sustainable, and contextually appropriate.
Risk Control Measures Selection
- Employ a hierarchy of controls for risk mitigation, including:
- Elimination,
- Substitution,
- Engineering controls,
- Administrative controls,
- Personal protective equipment.
Risk Acceptance and Review
- Organizations establish their own risk acceptance based on available resources and situational context.
- Regular reviews of risk assessments are vital to adapt to new information, changes, or incidents.
Biosafety vs Biosecurity
- Biosafety focuses on biological agents' properties and lab usage, while biosecurity evaluates the malicious use potential of agents.
- Both risk assessments involve common elements like good laboratory practices, personnel qualifications, and emergency planning.
Conflicts Between Biosafety and Biosecurity
- Ensuring laboratory access security can impede response efforts during emergencies, highlighting the need for balanced controls.### Laboratory Biosecurity Measures
- New guidelines recommend limiting biohazard sign information.
- Required information includes:
- Laboratory biosafety level
- Investigator's name and telephone number
- Emergency contact details
Conflicts Between Biosafety and Biosecurity
-
Biosafety focuses on:
- Open information and communication
- Recognizable samples for easy identification
- Plans to rescue lab workers during emergencies
- Transport of biological materials following established protocols
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Biosecurity emphasizes:
- Restricted information display to enhance security
- Limited communication for safety
- Coding samples stored to protect sensitive data
- Maintaining closed barriers during emergencies to restrict access
- Addressing gaps in communication between sender and receiver regarding materials
- Ensuring contingency plans contain limited information for first aid teams to follow during emergencies
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Description
Test your knowledge on implementing a Biorisk Management System, focusing on continual improvement through the PDCA cycle. This quiz encompasses key strategies for effective program management and practices. Review essential concepts and enhance your understanding of Biorisk management.
