Biorisk Management in Laboratories

Biorisk Management

• The primary purpose of biorisk management is to minimize the risk of adverse effects on human health and the environment.

Definition of Biorisk

• Biorisk refers to the potential for harm or damage to humans, animals, plants, or the environment arising from the use of biological agents, including microorganisms, toxins, and recombinant nucleic acid molecules.

Sources of Biorisk

• The sources of biorisk include biological agents, such as bacteria, viruses, and toxins, as well as genetic materials and recombinant nucleic acid molecules.

AMP Model in Biorisk Management

• The AMP MODEL is a framework for biorisk management that involves Assessment, Management, and Prevention of biorisks.

Initial Step in Biorisk Management

• The initial step in implementing a biorisk management process is to identify and assess the risks associated with biological agents and activities.

BRM Encompasses

• Biorisk Management (BRM) encompasses the identification of hazards, assessment of risks, and implementation of controls to mitigate or eliminate risks.

Definition of Hazard

• In the context of risk assessment, a hazard refers to a biological, chemical, physical, or ergonomic factor that has the potential to cause harm to people, animals, or the environment.

Malevolence

• Malevolence refers to the likelihood of harm to occur, as an expression of intention to inflict evil, injury, or damage.

Identifying At-Risk Hosts

• The purpose of identifying the at-risk hosts in risk assessment is to determine the individuals or populations that are most susceptible to harm from biological agents.

Engineering Controls

• Engineering controls involve physical changes in work stations, equipment, or production facilities to reduce or prevent exposure to hazards.

Least Effective Measure

• The least effective measure for controlling risks in a laboratory setting is personal protective equipment (PPE).

Risk Characterization

• The overall risk characterization in risk assessment involves evaluating the likelihood and impact of harm or damage from biological agents.

Substitution

• Substitution involves replacing procedures or biological agents with similar entities in order to reduce risk.

Performance Evaluation

• The purpose of performance evaluation in biorisk management system is to monitor and assess the effectiveness of risk controls and identify areas for improvement.

Administrative Controls

• Administrative controls refer to policies, procedures, and guidelines that are implemented to reduce or prevent exposure to hazards.

Hazard Assessment

• Hazard assessment involves identifying and evaluating the hazards associated with biological agents and activities.