Biorisk Assessment Overview
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Questions and Answers

Which step involves identifying hazards associated with an infectious agent or material?

  • Evaluate the risk
  • Gather information (correct)
  • Select and implement risk control measures
  • Develop a risk control strategy
  • What is the minimum time that 5.25% hypochlorite (bleach) should be in contact with a surface for effective decontamination?

  • 5 minutes
  • 20 minutes (correct)
  • 15 minutes
  • 10 minutes
  • When evaluating risk, which factor should be considered regarding laboratory staff?

  • Competencies and experience (correct)
  • Availability of safety equipment
  • Location of the laboratory
  • Type of infectious agent handled
  • Which of the following measures is NOT a routine agent for surface decontamination?

    <p>Nitric acid</p> Signup and view all the answers

    What should be done before disposing of strong acids or bases?

    <p>Neutralize them</p> Signup and view all the answers

    Which of the following pathogens does a 10% solution of household bleach inactivate in just 2 minutes?

    <p>HIV</p> Signup and view all the answers

    Which step in the risk assessment process involves the review of national and institutional regulations?

    <p>Select and implement risk control measures</p> Signup and view all the answers

    What is the purpose of a biorisk assessment?

    <p>To prevent laboratory-acquired infections</p> Signup and view all the answers

    Which of the following is an example of a physical decontamination method?

    <p>UV radiation</p> Signup and view all the answers

    In the risk assessment process, what does reviewing risks and risk control measures focus on?

    <p>Developing and implementing control measures</p> Signup and view all the answers

    What is the correct disposal method for contaminated sharps like needles and scalpels?

    <p>They must be placed in puncture-proof containers fitted with covers.</p> Signup and view all the answers

    What must be done to contaminated material if it is to be reused or recycled?

    <p>It must first be decontaminated and then washed.</p> Signup and view all the answers

    Which of the following materials can be reused or recycled without any prior treatment?

    <p>Uncontaminated (non-infectious) material</p> Signup and view all the answers

    What is the first step in disposing of contaminated material for disposal?

    <p>It must be decontaminated onsite.</p> Signup and view all the answers

    What is the proper action for laboratory coats that have been in contact with infectious materials?

    <p>They must be removed before exiting the laboratory area.</p> Signup and view all the answers

    What should happen to pipettes and glass objects before disposal?

    <p>They should be placed inside a firm cardboard container.</p> Signup and view all the answers

    What type of waste must always be treated as infectious and handled accordingly?

    <p>Contaminated sharps</p> Signup and view all the answers

    What must be done to contaminated material before it can be considered uncontaminated?

    <p>It has to undergo both chemical and physical decontamination.</p> Signup and view all the answers

    Which of the following describes contaminated materials for disposal regarding their treatment?

    <p>They must be decontaminated onsite or safely stored before transportation.</p> Signup and view all the answers

    Study Notes

    Biorisk Assessment Overview

    • Biorisk assessment reviews laboratory practices, control measures, biosafety standards, and the properties of infectious agents.
    • Aims to prevent laboratory-acquired infections (LAIs) and exposure to high-risk pathogens.
    • Evaluates potential risks to laboratory personnel and possible outcomes of exposure.
    • Provides strategies to mitigate identified risks, conducted by institutions periodically using standardized checklists.

    Steps in Performing Risk Assessment

    • Gather information on hazards associated with infectious agents or materials.
    • Evaluate risks related to activities that may cause exposure to these agents.
    • Develop a risk control strategy that considers staff competencies and resource availability.
    • Select and implement measures that align with national and institutional regulations.
    • Review and continuously assess risks and control measures to ensure effectiveness.

    Common Agents for Surface Decontamination

    • Effective decontamination agents include heat (250° C for 15 minutes), ethylene oxide, glutaraldehyde (2%), 10% hydrogen peroxide, and 5.25% hypochlorite (10% bleach).
    • Household bleach can inactivate hepatitis B virus in 10 minutes and HIV in 2 minutes.
    • Bleach should remain in contact with surfaces for at least 20 minutes for effective decontamination.

    Disposal of Contaminated Waste

    • Strong acids or bases must be neutralized prior to disposal; do not add water to concentrated acids.
    • Personal protective equipment (PPE) that may contact infectious material must be removed before exiting the laboratory and should not leave the facility.
    • Contaminated PPE must be properly disposed of, ensuring it does not leave the laboratory.

    Treatment of Laboratory Waste

    • Uncontaminated (Non-infectious) Material: Can be reused, recycled, or disposed of as general waste.
    • Contaminated Sharps (e.g., needles, scalpels): Must be collected in puncture-proof containers and treated as infectious waste.
    • Contaminated Material for Reuse: Should be decontaminated before washing and treating as non-infectious.
    • Contaminated Material for Disposal: Requires decontamination on-site or safe storage before transportation for further decontamination and disposal.

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    Description

    This quiz covers the essential aspects of biorisk assessment, including laboratory practices, biosafety standards, and risk mitigation strategies. Learn how to evaluate and prevent laboratory-acquired infections (LAIs) and the importance of reviewing infectious agents' hazardous characteristics. Test your knowledge on best practices in laboratory safety and risk management.

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