Biorisk Management: Risk Assessment and the AMP Model

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary goal of risk assessment in biosafety implementation?

  • To make consistent decisions even with uncertainty and incomplete data (correct)
  • To focus solely on the receiving environment
  • To prioritize national policies over public perception
  • To make entirely objective decisions

What are the two types of risk assessments conducted in the lab?

  • Cultural-based and religious-based
  • Agent-based and protocol-based (correct)
  • Protocol-based and socio-economic-based
  • Environmental-based and community-based

What is the second step in conducting a risk assessment?

  • Estimate the likelihood of the adverse effects (correct)
  • Estimate the overall potential environmental impact
  • Identify potential adverse effects on human and animal health
  • Evaluate the consequences of the identified effects

What is a critical factor involved in risk assessment?

<p>Past experience (C)</p> Signup and view all the answers

What is the final step in conducting a risk assessment?

<p>Estimate the overall potential environmental impact (C)</p> Signup and view all the answers

What is the purpose of identifying risks outside the lab?

<p>To determine the risk to the community (A)</p> Signup and view all the answers

What is the primary goal of a biological risk assessment?

<p>To determine the relative level of risk and guide mitigation decisions (D)</p> Signup and view all the answers

What is the purpose of biosafety risk assessment?

<p>To consider every aspect of operations that involves infectious disease agents or toxins (D)</p> Signup and view all the answers

What is the outcome of a biological risk assessment?

<p>A determination of the relative level of risk and guidance on mitigation decisions (B)</p> Signup and view all the answers

What is the difference between biosafety and biosecurity risk assessments?

<p>Biosafety focuses on infectious disease agents, while biosecurity focuses on institution assets and vulnerabilities (C)</p> Signup and view all the answers

What is the purpose of estimating the likelihood of exposure to an agent?

<p>To estimate the risk of harm from an infection (D)</p> Signup and view all the answers

What is the final step in the risk assessment process?

<p>Asking the question 'Is the risk acceptable?' (B)</p> Signup and view all the answers

What is the purpose of BioRAM?

<p>To facilitate laboratory biosafety and biosecurity risk assessments (B)</p> Signup and view all the answers

What is the outcome of risk evaluation in an institution?

<p>It drives investment decisions in the institution (B)</p> Signup and view all the answers

What is a factor that influences risk evaluation and acceptance?

<p>Culture and experience (C)</p> Signup and view all the answers

What is the name of the iPhone app for risk assessment?

<p>iSafe (B)</p> Signup and view all the answers

What is the process of determining whether a risk is high or low, and whether it’s acceptable or not?

<p>Risk evaluation (B)</p> Signup and view all the answers

What is the relationship between an institution's risk tolerance and its resource allocation?

<p>Risk-averse institutions spend more resources to reduce risks (A)</p> Signup and view all the answers

What type of Mycobacterium tuberculosis does the lab worker discover in the culture?

<p>Extremely Drug Resistant (XDR) (D)</p> Signup and view all the answers

Why does the local animal rights group want to steal the XDR culture?

<p>To generate publicity and get attention (B)</p> Signup and view all the answers

How can the risk of exposure to Mycobacterium tuberculosis be lowered in a laboratory?

<p>By using personal protective equipment (B)</p> Signup and view all the answers

What would be the effect of implementing strict physical security measures in the laboratory?

<p>It would decrease the likelihood of a security breach (D)</p> Signup and view all the answers

How can the consequences of exposure to Mycobacterium tuberculosis be lowered?

<p>By administering a vaccine (D)</p> Signup and view all the answers

What is the goal of biosafety and biosecurity measures?

<p>To lower the likelihood and consequences of exposure to infectious agents (B)</p> Signup and view all the answers

What is the primary goal of estimating the likelihood of adverse effects in a laboratory setting?

<p>To identify possible pathways for a hazard to lead to adverse effects (B)</p> Signup and view all the answers

What is the purpose of considering modifying factors in estimating the likelihood of adverse effects?

<p>To evaluate the persistence of the agent in the environment (C)</p> Signup and view all the answers

What is the definition of a 'Marginal' consequence in a laboratory setting?

<p>Minimal adverse health effects (D)</p> Signup and view all the answers

What is the score given to a hazard that is expected to occur in most circumstances?

<p>4 (B)</p> Signup and view all the answers

What is the purpose of Step 2 in the risk assessment process?

<p>To identify possible pathways and the likelihood of a hazard leading to adverse effects (A)</p> Signup and view all the answers

What is the relationship between Step 2 and Step 3 in the risk assessment process?

<p>Step 2 estimates the likelihood, and Step 3 evaluates the consequence (A)</p> Signup and view all the answers

Flashcards

Risk Assessment

A process for making informed decisions about potential risks, considering scientific facts, past experience, and various influential factors.

Adverse Effects

The possible negative effects on humans, animals, or the environment resulting from a specific activity or event.

Likelihood

The chance or probability that an identified adverse effect will actually occur.

Consequences

The severity or magnitude of the consequences if an adverse effect occurs.

Signup and view all the flashcards

Risk Management Strategies

Strategies designed to reduce or minimize the likelihood or consequences of identified risks.

Signup and view all the flashcards

Biological Risk Assessment

The process of systematically determining the potential risks associated with a specific activity or situation involving biological agents.

Signup and view all the flashcards

Identifying Biological Agents

The identification of biological agents and factors that can contribute to or modify risk.

Signup and view all the flashcards

Identifying Routes of Transmission

The identification of the primary routes or ways in which biological agents can spread or be transmitted.

Signup and view all the flashcards

Modifying Factors

Factors that influence the likelihood or consequences of a biological risk, such as the receiving environment, socio-economic factors, cultural practices, and public perception.

Signup and view all the flashcards

Risk Evaluation

The evaluation of the likelihood and consequences of a biological risk, determining if the overall risk is high or low and acceptable or not.

Signup and view all the flashcards

Risk Mitigation

The process of implementing measures to reduce or control identified biological risks.

Signup and view all the flashcards

Biorisk Management

A comprehensive approach to managing the risks associated with biological agents, encompassing assessment, mitigation, and ongoing performance monitoring.

Signup and view all the flashcards

BioRAM

A computerized tool specifically designed for conducting biosafety and biosecurity risk assessments in laboratories.

Signup and view all the flashcards

iSafe

A mobile application for use on iPhones, intended to facilitate risk assessments, including biological risk assessments.

Signup and view all the flashcards

Acceptable Risk

The level of risk that is considered acceptable or tolerable, which can vary based on context and factors like culture, experience, resources, and management.

Signup and view all the flashcards

Personal Protective Equipment (PPE)

Measures taken to reduce the likelihood of exposure to biological agents, such as wearing gloves, masks, or using other protective equipment.

Signup and view all the flashcards

Biohazards

Biological agents that have the potential to cause harm to humans, animals, or the environment.

Signup and view all the flashcards

Containment Measures

Measures taken to control the spread of biological agents, such as physical barriers, ventilation systems, and other engineering controls.

Signup and view all the flashcards

Biosecurity Risk Assessment

The assessment of the likelihood and consequences of risks associated with the intentional or unintentional release of biological agents.

Signup and view all the flashcards

Biosafety Risk Assessment

The assessment of the likelihood and consequences of risks associated with the accidental exposure to biological agents in a laboratory or research setting.

Signup and view all the flashcards

Performance Monitoring

The evaluation of the effectiveness of risk management strategies in mitigating identified risks.

Signup and view all the flashcards

Likelihood Levels

A classification system used in risk assessments to indicate the likelihood of a particular event occurring.

Signup and view all the flashcards

Consequence Levels

A classification system used in risk assessments to indicate the severity of the consequences if a particular event occurs.

Signup and view all the flashcards

Vaccination

A risk mitigation strategy that involves the use of vaccines to prevent infection by biological agents.

Signup and view all the flashcards

Therapeutics

A risk mitigation strategy that involves the use of medications or treatments to alleviate or cure infections caused by biological agents.

Signup and view all the flashcards

Physical Barriers

The use of physical barriers such as walls, doors, or windows to control the movement of biological agents.

Signup and view all the flashcards

International Biosecurity Risks

Biological risks associated with the transfer of biological agents between countries or regions.

Signup and view all the flashcards

Biosecurity Technology

The use of advanced technologies to detect, monitor, and respond to potential biosecurity threats.

Signup and view all the flashcards

Emerging Infectious Diseases

The study of the factors that contribute to the emergence and spread of infectious diseases.

Signup and view all the flashcards

Epidemiological Modeling

The use of data analysis and modeling techniques to predict and manage the spread of infectious diseases.

Signup and view all the flashcards

Laboratory Biosafety

The practice of using laboratory safety procedures to prevent the exposure of personnel to biological agents.

Signup and view all the flashcards

Study Notes

Risk Assessment

  • Based on scientific facts, risk assessment allows for consistent decision-making despite uncertainty and incomplete data.
  • Factors involved in risk assessment: past experience, receiving environment, socio-economics, cultural, religious, national policies, and public perception.
  • Risk assessment can be subjective in nature.

Conducting a Risk Assessment

  • Identify potential adverse effects on human and animal health and/or the environment.
  • Estimate the likelihood of these adverse effects being realized.
  • Evaluate the consequences should the identified effects be realized (the risk).
  • Consider appropriate risk-management strategies.
  • Estimate the overall potential environmental impact.

Step 1: Identify Risks

  • Identify biological agents and factors that can modify the risk.
  • Identify main routes of transmission and how to modify the risk.
  • Consider risks outside the lab, including risks to the community and biosecurity threats.

Step 2: Estimate the Likelihood of Adverse Effects

  • Identifies possible pathways and likelihood of a hazard leading to adverse effects.
  • Takes into consideration agent characteristics, handling and use procedures, and modifying factors.

Step 3: Estimate the Consequences

  • Evaluates the magnitude of the consequences of the possible adverse effects.
  • Consequences vary on a case-by-case basis, depending on the agent and activity involved.

Levels of Likelihood and Consequences

  • Likelihood levels: Highly Unlikely, Unlikely, Likely, Highly Likely.
  • Consequence levels: Minimal, Marginal, Moderate, High, Very High.

Risk Mitigation

  • Risk can be modified by mitigation measures such as personal protective equipment, vaccines, physical barriers, and availability of therapeutics.
  • Mitigation measures can lower the likelihood and consequences of risk.

Biorisk Management

  • Biorisk management involves assessment, mitigation, and performance.
  • Risk assessment is an analytical procedure to characterize biological risks in a facility or operation.
  • Biological risk assessments can be classified into biosafety and biosecurity risk assessments.

Biological Risk Assessment Tools

  • BioRAM: a computerized risk assessment tool for laboratory biosafety and biosecurity risk assessments.
  • iSafe: an iPhone app for risk assessment.

Risk Evaluation

  • Risk evaluation determines whether a risk is high or low and whether it's acceptable or not.
  • What is considered "acceptable" risk can vary with culture, experience, resources, management, and current events.
  • Risk evaluation drives investment decisions in an institution.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Biorisk Management Quiz
16 questions

Biorisk Management Quiz

ExceedingCarolingianArt avatar
ExceedingCarolingianArt
Risk Management in Clinical Laboratories
60 questions
Risk Management in Clinical Laboratories
48 questions
Use Quizgecko on...
Browser
Browser