Biopharmaceuticals and Biosimilars Quiz

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What is the main purpose of a patent for a biopharmaceutical?

To limit the efficacy of the drug

To increase competition in the pharmaceutical market

To grant the company exclusive manufacturing rights (correct)

To prevent the development of generic drugs

Which company developed the first biopharmaceutical, insulin, in 1982?

Novartis

Genentech (correct)

Eli Lily

Pfizer

What is a biological patent mainly used for in the field of biopharmaceuticals?

To allow unrestricted access to the protected invention

To give exclusive rights to the patent holder for a limited time (correct)

To limit the number of approved biologics

To encourage the development of generic drugs

Why is a biological patent crucial for developers of biopharmaceuticals?

To protect their investment in drug development Signup and view all the answers

Which continent has perceived requirements for patents on biopharmaceuticals as more difficult to satisfy?

Europe Signup and view all the answers

How has the number of patents granted for biopharmaceuticals changed since the 1970s?

Increased substantially Signup and view all the answers

What is the main aim of the course Biologics and Biopharmaceuticals (PHEN607)?

To introduce the main concepts for drug discovery of biopharmaceuticals Signup and view all the answers

Who is the course instructor for Week 9?

Dr. AbdelMageed Signup and view all the answers

What role does Dr. Rana A. Youness have in the course?

Lead instructor for all weeks Signup and view all the answers

Which faculty is responsible for the course Biologics and Biopharmaceuticals?

Faculty of Pharmaceutical Engineering Signup and view all the answers

When are Dr. Rana Youness' office hours?

Tuesday 12-1 pm Signup and view all the answers

What is Dr. Rana Youness' area of expertise?

Molecular Genetics and Biochemistry Signup and view all the answers

What did Friedrich Miescher discover in 1869?

Nucleic acid in surgical bandages Signup and view all the answers

Who received the Nobel Prize in 1962 for deciphering the double helix structure of DNA?

Watson and Crick Signup and view all the answers

What was the outcome of Griffith's Experiment in 1918?

The R strain transformed into the S strain Signup and view all the answers

What conclusion did Griffith make from his experiment?

A chemical component transforms bacterial cells Signup and view all the answers

What did Avery, McLeod, and McCarty experiment show?

DNA can be chemically isolated from cell extracts Signup and view all the answers

What process did bacterial transformation involve according to the text?

Horizontal gene transfer between bacteria Signup and view all the answers

What is the weightage of the final exam in the overall course assessment?

40% Signup and view all the answers

Which statement best describes biopharmaceuticals?

Proteins and nucleic acids used for therapeutic purposes Signup and view all the answers

What is the main difference between biologics and biosimilars?

Biologics are protein-derived molecules grown in cells, whereas biosimilars are purified into active agents Signup and view all the answers

Which assessment method carries the least weight in the course evaluation?

Assignments within tutorial sessions Signup and view all the answers

What is the share of biopharmaceuticals in the market according to the text?

~100% Signup and view all the answers

Which of the following is NOT an Intended Learning Outcome (ILO) mentioned in the text?

Explaining the process of protein synthesis Signup and view all the answers

Which components make up a nucleotide?

Sugar, Nitrogenous Base, Phosphate group Signup and view all the answers

What is the difference between a nucleoside and a nucleotide?

Presence of a Phosphate group Signup and view all the answers

How many hydrogen bonds can form between G and C in DNA?

3 hydrogen bonds Signup and view all the answers

Which molecule contains Uracil instead of Thymine?

RNA Signup and view all the answers

What is the function of Phosphodiester bonds in DNA?

Connect Nucleotides in the same strand Signup and view all the answers

What did Chargaff discover about the concentration of bases in DNA molecules?

[A] = [T] and [G] = [C] Signup and view all the answers