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Questions and Answers
Which of the following components is NOT required to construct a complete model of the neuron?
Which of the following components is NOT required to construct a complete model of the neuron?
The circuit model of a soma with an active axon would look like which of the following?
The circuit model of a soma with an active axon would look like which of the following?
What is the primary mechanism for communication between neurons?
What is the primary mechanism for communication between neurons?
The Donnan equilibrium describes the distribution of ions across a membrane when:
The Donnan equilibrium describes the distribution of ions across a membrane when:
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Which equation is used to calculate the steady-state membrane potential due to the distribution of multiple ion species?
Which equation is used to calculate the steady-state membrane potential due to the distribution of multiple ion species?
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Which of the following is NOT a component of the circuit model for a cell membrane?
Which of the following is NOT a component of the circuit model for a cell membrane?
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The membrane potential of a neuron is primarily determined by the distribution of which ion?
The membrane potential of a neuron is primarily determined by the distribution of which ion?
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Which of the following is NOT a characteristic of an action potential?
Which of the following is NOT a characteristic of an action potential?
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The Nernst equation is used to calculate the equilibrium potential for which of the following?
The Nernst equation is used to calculate the equilibrium potential for which of the following?
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Which of the following is NOT a factor that influences the resting membrane potential of a neuron?
Which of the following is NOT a factor that influences the resting membrane potential of a neuron?
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Study Notes
Circuit Model for Cell Membrane
- The cell membrane can be modeled using a circuit that incorporates capacitance, resistance, and electromotive properties.
- The circuit model includes membrane capacitance and the resistive and electromotive properties of ion-specific channels.
Properties of Ion Channels
- Electromotive force properties: the concentration gradient for each ion creates a force that drives the ion through the channel at a constant rate.
- Nernst potential for each ion is modeled as a battery.
- The polarity of the battery is determined by the concentration gradient, with the ground on the outside of the membrane.
Resistive Properties
- Ion channels have resistance that resists the movement of ions through the channel.
- Resistance is mainly due to collisions with the channel's wall, resulting in energy loss as heat.
- The equivalent circuit for N ion channels is a single resistor and a battery.
Capacitive Properties
- Capacitance occurs when electrical conductors are separated by an insulating material, such as the neuron membrane.
- Ions do not move through the membrane except through ion channels.
- The equivalent circuit includes a capacitor, a resistor, and a battery.
Thevenin Equivalent Circuit
- A reduced circuit model can be used to simplify the analysis of the cell membrane circuit.
Example Problem
- The membrane potential (Vm) can be calculated using mesh analysis and the circuit model.
- The solution involves finding the current (I) and using it to calculate Vm.
Na-K Pump
- The Na-K pump maintains a steady flow of ions even when the membrane is at rest.
- K+ ions are pumped out of the cell, while Na+ ions are pumped in.
Model of a Whole Neuron
- A complete model of a neuron can be constructed by including multiple dendritic branches, a soma, and an axon.
- The circuit model can be used to analyze and solve neuron circuit models.
Signaling among Neurons
- Signaling occurs among neurons through the interaction between adjacent neurons, where the current from one neuron stimulates the next.
- The process involves the presynaptic terminal and the postsynaptic terminal.
- Understanding the circuit model of neurons is essential for analyzing and solving the process of communication among neurons.
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Description
Test your knowledge on circuit models for the cell membrane in the field of biomedical engineering. Questions cover topics such as membrane capacitance, electromotive properties, and resistive properties in nerve cells.
