Biomaterials in Hemostasis and Thrombosis

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Questions and Answers

Which of the following best defines hemostasis?

  • The activation and aggregation of platelets
  • The stopping of hemorrhage or bleeding (correct)
  • The release of thrombin and fibrinogen
  • The formation of a blood clot in the wrong place

What is thrombosis?

  • The formation of a blood clot in the wrong place (correct)
  • The activation and aggregation of platelets
  • The stopping of hemorrhage or bleeding
  • The release of thrombin and fibrinogen

Which factors contribute to hemostasis?

  • Platelet adhesion, activation, aggregation, and release
  • GpIb, vWF, collagen, and biomaterials
  • Endothelium, biomaterial surface, platelets, and blood clotting factors (correct)
  • Blood flow, biomaterial surface, and fluid dynamic factors

Which of the following is a common complication of stents?

<p>Intimal Hyperplasia (D)</p> Signup and view all the answers

Which drug is commonly used in drug-eluting stents?

<p>Rapamycin (C)</p> Signup and view all the answers

What is the main purpose of evaluating hemocompatibility of biomaterials?

<p>To improve the compatibility of materials with blood (B)</p> Signup and view all the answers

Which of the following proteins is responsible for breaking down fibrin and interfering with fibrin polymerization?

<p>Plasmin (D)</p> Signup and view all the answers

Which of the following factors is necessary for blood clotting?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following factors inhibits the activity of thrombin and other serine proteases?

<p>Antithrombins (D)</p> Signup and view all the answers

Which of the following drugs is used for anticoagulant and antithrombotic therapy?

<p>All of the above (D)</p> Signup and view all the answers

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