Biomarkers and Translational Research Quiz

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Questions and Answers

What is a biomarker?

  • A specific type of gene
  • A gene, protein/peptide, or metabolite used to indicate a physiological or pathological state (correct)
  • A type of disease characteristic
  • A type of protein used in drug design

What does translational research refer to?

  • Research involving translation of languages
  • Research focused on studying rare diseases
  • Research involved in translating biological findings to clinical applications (correct)
  • Research dedicated to studying genetic variations

Which category of biomarkers is used to estimate the emergence or development of a disease?

  • Therapeutic biomarkers
  • Prognostic biomarkers
  • Pathological biomarkers
  • Diagnostic biomarkers (correct)

What significant roles does computational biology play in regard to biomarkers?

<p>Discovering and validating new biomarkers, analyzing disease states, and drug design (D)</p> Signup and view all the answers

Complete the sentence: Cancer genomics is the study of _________________.

<p>The human cancer genome to search for the full collection of genes and mutations (D)</p> Signup and view all the answers

Which of the following is a characteristic of competitive enzyme inhibitors?

<p>They do not affect Vmax (C)</p> Signup and view all the answers

What is the shape of an alpha helix?

<p>Coiled (C)</p> Signup and view all the answers

Which amino acids destabilize the alpha helix?

<p>Glycine and Proline (C)</p> Signup and view all the answers

In beta pleated sheet, how do the polypeptide chains line up?

<p>Side by side (C)</p> Signup and view all the answers

What is the effect of reversible non-competitive enzyme inhibitors on Km value?

<p>It remains unchanged (D)</p> Signup and view all the answers

Which of the following is a distinguishing characteristic of competitive enzyme inhibitors?

<p>They do not affect the Km value (C)</p> Signup and view all the answers

What is the primary factor contributing to the stability of an alpha helix structure?

<p>Hydrogen bonds between amino acid residues (A)</p> Signup and view all the answers

Which of the following amino acids is known to destabilize the alpha helix structure?

<p>Glycine and proline (C)</p> Signup and view all the answers

What effect do reversible non-competitive enzyme inhibitors have on the Vmax value?

<p>They decrease the Vmax value (D)</p> Signup and view all the answers

In beta pleated sheets, how do the polypeptide chains line up?

<p>In an antiparallel fashion (D)</p> Signup and view all the answers

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