15 Questions
What is a biomarker?
A gene, protein/peptide, or metabolite used to indicate a physiological or pathological state
What does translational research refer to?
Research involved in translating biological findings to clinical applications
Which category of biomarkers is used to estimate the emergence or development of a disease?
Diagnostic biomarkers
What significant roles does computational biology play in regard to biomarkers?
Discovering and validating new biomarkers, analyzing disease states, and drug design
Complete the sentence: Cancer genomics is the study of _________________.
The human cancer genome to search for the full collection of genes and mutations
Which of the following is a characteristic of competitive enzyme inhibitors?
They do not affect Vmax
What is the shape of an alpha helix?
Coiled
Which amino acids destabilize the alpha helix?
Glycine and Proline
In beta pleated sheet, how do the polypeptide chains line up?
Side by side
What is the effect of reversible non-competitive enzyme inhibitors on Km value?
It remains unchanged
Which of the following is a distinguishing characteristic of competitive enzyme inhibitors?
They do not affect the Km value
What is the primary factor contributing to the stability of an alpha helix structure?
Hydrogen bonds between amino acid residues
Which of the following amino acids is known to destabilize the alpha helix structure?
Glycine and proline
What effect do reversible non-competitive enzyme inhibitors have on the Vmax value?
They decrease the Vmax value
In beta pleated sheets, how do the polypeptide chains line up?
In an antiparallel fashion
Test your knowledge on biomarkers, translational research, and clinical bioinformatics with this quiz. Learn about the definition of biomarkers and their categories, as well as their importance in indicating physiological or pathological states.
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