Podcast
Questions and Answers
Which of the following best describes a diagnostic biomarker?
Which of the following best describes a diagnostic biomarker?
- A marker that indicates the likely course of a disease regardless of treatment.
- A protein used in immunohistochemistry to analyze tissue samples.
- A biological indicator that helps identify the presence of a disease. (correct)
- A molecule that predicts a patient's response to a specific therapy.
A patient with a p53 mutation in a tumor is likely to have which type of biomarker?
A patient with a p53 mutation in a tumor is likely to have which type of biomarker?
- A predictive biomarker, indicating response to a specific therapy.
- A diagnostic biomarker, confirming the presence of a disease.
- A therapeutic biomarker, indicating a successful treatment.
- A prognostic biomarker, indicating a poor disease outlook. (correct)
What is the purpose of a predictive biomarker in cancer treatment?
What is the purpose of a predictive biomarker in cancer treatment?
- To predict the overall outcome of the disease.
- To identify the presence of a tumor.
- To analyze tissue samples at cellular level.
- To determine how a patient will respond to a certain therapy. (correct)
Which of the following best describes adjuvant therapy?
Which of the following best describes adjuvant therapy?
Immunohistochemistry is a technique used to analyse...
Immunohistochemistry is a technique used to analyse...
Flashcards
Diagnostic Biomarker
Diagnostic Biomarker
A biological indicator that helps doctors determine if a patient has a specific disease.
Prognostic Biomarker
Prognostic Biomarker
A biological indicator that helps predict the likely course of a disease, even with treatment.
Predictive Biomarker
Predictive Biomarker
A biological indicator that helps predict how a patient will respond to a specific treatment.
Immunohistochemistry
Immunohistochemistry
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Adjuvant Anti-Cancer Therapy
Adjuvant Anti-Cancer Therapy
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Study Notes
Diagnostic Biomarkers
- Diagnostic biomarkers are biological indicators (genes, proteins, etc.) that detect diseases like cancer.
- Example: CD20 is a biomarker for B-cell lymphoma.
Prognostic Biomarkers
- Prognostic biomarkers predict disease outcome (cancer) regardless of treatment.
- Example: p53 mutation signifies poor prognosis in many cancers.
Predictive Biomarkers
- Predictive biomarkers show how a patient responds to treatment.
- Example: EGFR is an indicator for tyrosine kinase inhibitors in small cell lung cancer.
Immunohistochemistry
- Immunohistochemistry (IHC) is a lab technique to analyze proteins.
- Example: Horseradish peroxidase is used in IHC.
Adjuvant Anti-Cancer Therapy
- Adjuvant therapy is additional cancer treatment given after primary treatment (surgery etc.).
- Types include: immunotherapy, targeted therapy, radiation, and chemotherapy.
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