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Biomarkers and Cancer Treatment Quiz

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Questions and Answers

Which of the following best describes a diagnostic biomarker?

A marker that indicates the likely course of a disease regardless of treatment.

A protein used in immunohistochemistry to analyze tissue samples.

A biological indicator that helps identify the presence of a disease. (correct)

A molecule that predicts a patient's response to a specific therapy.

A patient with a p53 mutation in a tumor is likely to have which type of biomarker?

A predictive biomarker, indicating response to a specific therapy.

A diagnostic biomarker, confirming the presence of a disease.

A therapeutic biomarker, indicating a successful treatment.

A prognostic biomarker, indicating a poor disease outlook. (correct)

What is the purpose of a predictive biomarker in cancer treatment?

To predict the overall outcome of the disease.

To identify the presence of a tumor.

To analyze tissue samples at cellular level.

To determine how a patient will respond to a certain therapy. (correct)

Which of the following best describes adjuvant therapy?

<p>An additional therapy given after the primary cancer treatment. (D)</p> Signup and view all the answers

Immunohistochemistry is a technique used to analyse...

<p>proteins expression (B)</p> Signup and view all the answers

Study Notes

Diagnostic Biomarkers

Diagnostic biomarkers are biological indicators (genes, proteins, etc.) that detect diseases like cancer.
Example: CD20 is a biomarker for B-cell lymphoma.

Prognostic Biomarkers

Prognostic biomarkers predict disease outcome (cancer) regardless of treatment.
Example: p53 mutation signifies poor prognosis in many cancers.

Predictive Biomarkers

Predictive biomarkers show how a patient responds to treatment.
Example: EGFR is an indicator for tyrosine kinase inhibitors in small cell lung cancer.

Immunohistochemistry

Immunohistochemistry (IHC) is a lab technique to analyze proteins.
Example: Horseradish peroxidase is used in IHC.

Adjuvant Anti-Cancer Therapy

Adjuvant therapy is additional cancer treatment given after primary treatment (surgery etc.).
Types include: immunotherapy, targeted therapy, radiation, and chemotherapy.

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Description

This quiz explores the different types of biomarkers and their roles in cancer diagnosis, prognosis, and predictive treatment responses. Additionally, it covers techniques like immunohistochemistry and adjuvant cancer therapies. Test your knowledge on these essential concepts in oncology!