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Questions and Answers
What is required to achieve greater refractive power in a lens?
What is required to achieve greater refractive power in a lens?
What is the primary function of the Lens in the human eye?
What is the primary function of the Lens in the human eye?
In which type of fish does the lens move closer to the retina for near vision?
In which type of fish does the lens move closer to the retina for near vision?
What is the main function of the Pecten in the avian eye?
What is the main function of the Pecten in the avian eye?
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What is the shape of the lens in adults, and what is its diameter?
What is the shape of the lens in adults, and what is its diameter?
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What is the shape of the lens in fish?
What is the shape of the lens in fish?
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How do some species, like fish, accommodate for near and far vision?
How do some species, like fish, accommodate for near and far vision?
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What is the composition of the lens in diving ducks?
What is the composition of the lens in diving ducks?
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What is the primary component of the zonules of Zinn?
What is the primary component of the zonules of Zinn?
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What happens to the shape of the lens when the ciliary muscles contract during accommodation?
What happens to the shape of the lens when the ciliary muscles contract during accommodation?
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What is the structure of the lens capsule?
What is the structure of the lens capsule?
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Why does the cornea have very little refractive power underwater?
Why does the cornea have very little refractive power underwater?
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What is the shape of the lens fibres in cross-section?
What is the shape of the lens fibres in cross-section?
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What is the main difference between cortical and nuclear fibres?
What is the main difference between cortical and nuclear fibres?
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What is the purpose of the high concentration of gap junctions in lens fibres?
What is the purpose of the high concentration of gap junctions in lens fibres?
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What is the reason for the difference in protein concentration between the lens nucleus and cortex?
What is the reason for the difference in protein concentration between the lens nucleus and cortex?
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How does the lens grow throughout life?
How does the lens grow throughout life?
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What is the diameter of the lens at birth?
What is the diameter of the lens at birth?
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What is the process by which lens epithelial cells transform into lens fibres?
What is the process by which lens epithelial cells transform into lens fibres?
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How do lens fibres grow and push under the epithelium and capsule?
How do lens fibres grow and push under the epithelium and capsule?
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What is the term for the alignment of newly produced lens fibre nuclei in the lens cortex?
What is the term for the alignment of newly produced lens fibre nuclei in the lens cortex?
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How do lens fibres in the adult lens differ from those in the embryonic lens?
How do lens fibres in the adult lens differ from those in the embryonic lens?
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What is the significance of the equatorial region in lens fibre formation?
What is the significance of the equatorial region in lens fibre formation?
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What is the relationship between lens fibre growth and the capsule?
What is the relationship between lens fibre growth and the capsule?
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What is the significance of the distinct arrangement of lens fibres at the poles, and how does this arrangement facilitate the lens's function?
What is the significance of the distinct arrangement of lens fibres at the poles, and how does this arrangement facilitate the lens's function?
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What is the primary difference between cortical and nuclear fibres, and how do these differences impact their functions?
What is the primary difference between cortical and nuclear fibres, and how do these differences impact their functions?
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How do the lens fibres communicate with each other, and what is the significance of this communication?
How do the lens fibres communicate with each other, and what is the significance of this communication?
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What is the mechanism by which the lens grows throughout life, and what is the significance of this growth?
What is the mechanism by which the lens grows throughout life, and what is the significance of this growth?
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How do the lens fibres differ in terms of protein concentration, and what is the significance of this difference?
How do the lens fibres differ in terms of protein concentration, and what is the significance of this difference?
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What is the significance of the lens being transparent and biconvex in structure?
What is the significance of the lens being transparent and biconvex in structure?
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What is the significance of the tight packing and interlocking of lens fibres, and how does this arrangement facilitate the lens's function?
What is the significance of the tight packing and interlocking of lens fibres, and how does this arrangement facilitate the lens's function?
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How does the lens grow throughout life, and what is the rate of this growth?
How does the lens grow throughout life, and what is the rate of this growth?
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What is the purpose of the zonules of Zinn, and what are they composed of?
What is the purpose of the zonules of Zinn, and what are they composed of?
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What is the relationship between the equator of the lens and the ciliary processes of the ciliary body?
What is the relationship between the equator of the lens and the ciliary processes of the ciliary body?
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What happens to the shape of the lens when the ciliary muscles contract during accommodation, and what is the effect on the pupil?
What happens to the shape of the lens when the ciliary muscles contract during accommodation, and what is the effect on the pupil?
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Why is the lens, unlike the cornea, able to change its dioptric power, allowing it to focus on distant or near objects?
Why is the lens, unlike the cornea, able to change its dioptric power, allowing it to focus on distant or near objects?
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What is the significance of the hexagonal cross-section of lens fibres, and how does it contribute to their compact packing?
What is the significance of the hexagonal cross-section of lens fibres, and how does it contribute to their compact packing?
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How do the nucleated cortical fibres and non-nucleated nuclear fibres differ in structure, and what is the significance of these differences?
How do the nucleated cortical fibres and non-nucleated nuclear fibres differ in structure, and what is the significance of these differences?
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What is the role of gap junctions in lens fibre communication, and how do they facilitate metabolic communication?
What is the role of gap junctions in lens fibre communication, and how do they facilitate metabolic communication?
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How do lens fibres grow throughout life, and what is the significance of this continuous growth?
How do lens fibres grow throughout life, and what is the significance of this continuous growth?
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What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and how does this alignment facilitate the lens's function?
What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and how does this alignment facilitate the lens's function?
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How do the lens fibres differ in terms of protein concentration, and what is the significance of this difference?
How do the lens fibres differ in terms of protein concentration, and what is the significance of this difference?
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Describe the process of lens fibre formation at the equator of the lens.
Describe the process of lens fibre formation at the equator of the lens.
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What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and what is this arrangement known as?
What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and what is this arrangement known as?
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How do lens fibres grow and push under the epithelium and capsule, and what is the significance of this process?
How do lens fibres grow and push under the epithelium and capsule, and what is the significance of this process?
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What is the significance of the gap junctions in lens fibres, and how do they facilitate communication between fibres?
What is the significance of the gap junctions in lens fibres, and how do they facilitate communication between fibres?
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Describe the structure of lens fibres in the adult lens, and how do they differ from those in the embryonic lens?
Describe the structure of lens fibres in the adult lens, and how do they differ from those in the embryonic lens?
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What is the significance of the equatorial region in lens fibre formation, and how does it contribute to the growth of the lens?
What is the significance of the equatorial region in lens fibre formation, and how does it contribute to the growth of the lens?
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What is the significance of the distinct arrangement of lens fibres at the poles, and how does it facilitate the lens's function?
What is the significance of the distinct arrangement of lens fibres at the poles, and how does it facilitate the lens's function?
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What is the mechanism by which lens epithelial cells transform into lens fibres, and what is the significance of this process?
What is the mechanism by which lens epithelial cells transform into lens fibres, and what is the significance of this process?
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How do lens fibres grow throughout life, and what is the significance of this growth?
How do lens fibres grow throughout life, and what is the significance of this growth?
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What is the purpose of the high concentration of gap junctions in lens fibres, and how does it facilitate lens fibre communication?
What is the purpose of the high concentration of gap junctions in lens fibres, and how does it facilitate lens fibre communication?
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What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and how does it facilitate lens function?
What is the significance of the alignment of newly produced lens fibre nuclei in the lens cortex, and how does it facilitate lens function?
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What is the relationship between lens fibre growth and the capsule, and how does it impact lens development?
What is the relationship between lens fibre growth and the capsule, and how does it impact lens development?
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Study Notes
Structure of the Lens
- The lens is a transparent, biconvex structure situated between the iris and vitreous body
- Anteriorly, the lens is less convex than posteriorly
- In adults, the lens is about 10 mm in diameter and 4 mm thick
Lens Capsule
- The capsule is an elastic basal membrane that envelopes the entire lens
- Thickest at the anterior and posterior poles (20 μm) and thinnest at the posterior pole (3 μm)
- Composed of 40 lamellae, each resembling a unit basal lamina
- Each lamella has collagen fibrils embedded in a glycosaminoglycan matrix
Lens Epithelium
- Found only on the anterior surface of the lens
- Functions include homeostasis and osmolarity, synthesis of crystallin, and production of lens fibers
- At the equator, epithelial cells elongate and form columnar cells, which become arranged in rows
Lens Fibers
- Constitute the main mass of the lens
- Formed by the multiplication and differentiation of lens epithelial cells at the equator
- Each fiber is 4 x 7 μm in size, hexagonal in cross-section, and up to 12 mm in length
- Fibers are tightly packed together and interlocked through their plasma membranes
- Older fibers form the nucleus, while younger fibers form the cortex
- Fibers do not meet at the poles, instead meeting at irregular lines called sutures
Microstructure of Lens Fibers
- High concentration of gap junctions for metabolic communication
- Cortical and nuclear fibers differ in structure
- Cortical fibers have a nucleus and organelles, while nuclear fibers have no nucleus or organelles
- Lens nucleus is more compact than the cortex, with a higher protein concentration (200-300 mg/ml vs 100-150 mg/ml)
Accommodation
- The lens allows the eye to focus at different distances
- Human accommodation involves deformation of the lens
- Some species accommodate through lateral movement of the lens or retina
- Deformation itself is not accommodation
Zonules of Zinn
- Suspensory ligaments that hold the lens in position
- Comprised of fibrillin (connective tissue with elastic properties)
- Diameter of 1-2 μm
- Involves in the accommodation process, allowing the lens to change its dioptric power
Growth and Development
- The lens grows throughout life
- At birth, the lens is about 6.5 mm in diameter
- In adults, the lens can reach 10 mm in diameter and up to 15 mm in older people
- The lens continues to grow and does not discard any of its cells, adding new cells to the central portion of the lens as lens fibers
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Description
Learn about the structure and function of the lens in the human eye, including its role in accommodation and how it changes shape to focus at different distances.