Questions and Answers
What will RNA interference (RNAi) allow for the removal of to generate a hypoallergenic strawberry?
Which of the following is NOT involved in an allergic response?
Which of the following IS involved in an allergic response? (Select multiple)
Which of the following would you test for to determine whether a patient is suffering from an allergic response?
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To determine if your brother's response to milk involves an allergy, which of the following would you test?
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What purpose does histamine serve in the Intracutaneous Test?
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Hypersensitivity is defined as:
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What is immunodeficiency?
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What is allergy?
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What is autoimmunity?
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What is an autoantibody?
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Autoantibodies are probably involved in ________.
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A potential cause of acquired autoimmunity is ________.
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Allergy to pollen is classified as ________.
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Study Notes
Hypoallergenic Strawberries
- RNA interference (RNAi) can be used to create "hypoallergenic" strawberries by targeting specific genes.
- The objective is to eliminate the gene that produces the allergenic protein or inhibit its mRNA.
Allergic Response Mechanisms
- Antigen presenting cells are crucial for presenting allergens to T helper cells.
- T helper cells activate other immune cells; cytotoxic T cells are not typically involved in allergic responses.
- Mast cells play a significant role in initiating allergic reactions by releasing histamine.
Identifying Allergies
- Elevated IgE levels indicate an allergic response, distinguishing it from viral infections.
- Testing antibody levels can help determine if symptoms are due to an allergy.
Stomach Problems and Milk Allergy
- Testing T helper cell activity is essential in confirming if an individual has a milk allergy.
Intracutaneous Test
- Histamine serves as a control in allergy tests to illustrate a typical allergic response.
Hypersensitivity
- Hypersensitivity encompasses immediate immune reactions to harmless antigens, characterized by rapid antibody-mediated responses.
- It includes various inappropriate immune responses, such as allergies and autoimmunity.
Immunodeficiency
- Immunodeficiency refers to a failure or insufficiency in any aspect of the immune system and can be either inherited or acquired.
Definitions of Allergy and Autoimmunity
- Allergy is defined as an immediate immune reaction to harmless antigens resulting from antibody-mediated responses.
- Autoimmunity occurs when the immune system mistakenly identifies self-antigens as foreign, leading to tissue damage.
Autoantibodies
- Autoantibodies are antibodies that target the body's own components, contributing to autoimmune diseases.
- Systemic lupus erythematosus is a condition where autoantibodies play a significant role in disease pathology.
Causes of Acquired Autoimmunity
- Molecular mimicry is a potential trigger of acquired autoimmunity, involving cross-reactivity between pathogens and self-antigens.
Pollen Allergy Classification
- Allergy to pollen is classified as immediate hypersensitivity, resulting in rapid immune responses upon exposure to allergens.
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Description
This quiz focuses on the mechanisms behind allergies, specifically relating to strawberries and their potential to cause severe allergic reactions. It explores the use of RNA interference (RNAi) in creating hypoallergenic variants by targeting the allergenic proteins involved. Test your knowledge on the genetic and immunological aspects of allergies.