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Questions and Answers
What tissue types are present in bone?
What tissue types are present in bone?
Hemopoiesis occurs in the yellow marrow of bones.
Hemopoiesis occurs in the yellow marrow of bones.
False
What is the primary function of the periosteum?
What is the primary function of the periosteum?
To promote bone growth in width, assist in fracture repair, nourish bone tissue, and serve as an attachment point for ligaments and tendons.
The ________ consists of the shaft of a long bone.
The ________ consists of the shaft of a long bone.
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Match the following bone cell types with their functions:
Match the following bone cell types with their functions:
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What is one of the main functions of bones?
What is one of the main functions of bones?
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The epiphyseal plate is found at the ends of bones, allowing for bone elongation.
The epiphyseal plate is found at the ends of bones, allowing for bone elongation.
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What type of marrow serves as a site of triglyceride storage in adult bones?
What type of marrow serves as a site of triglyceride storage in adult bones?
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What is the first step in endochondral ossification?
What is the first step in endochondral ossification?
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Growth in length of bones occurs through the activity of the epiphyseal plate.
Growth in length of bones occurs through the activity of the epiphyseal plate.
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What appears when the epiphyseal plate closes?
What appears when the epiphyseal plate closes?
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Bone can grow in thickness only by __________ growth at the periosteum.
Bone can grow in thickness only by __________ growth at the periosteum.
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Which of the following nutrients is NOT necessary for bone growth?
Which of the following nutrients is NOT necessary for bone growth?
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Which zone of the epiphyseal plate is responsible for the proliferation of cartilage cells?
Which zone of the epiphyseal plate is responsible for the proliferation of cartilage cells?
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Match the following terms with their definitions:
Match the following terms with their definitions:
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Thyroid hormones are not essential for bone growth.
Thyroid hormones are not essential for bone growth.
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What are the two primary hormones that stimulate bone growth during childhood?
What are the two primary hormones that stimulate bone growth during childhood?
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Remodeling of bone involves the destruction of new bone tissue.
Remodeling of bone involves the destruction of new bone tissue.
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What causes bone growth in diameter?
What causes bone growth in diameter?
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A __________ fracture is characterized by a series of microscopic fissures in the bone.
A __________ fracture is characterized by a series of microscopic fissures in the bone.
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Match the following fractures with their descriptions:
Match the following fractures with their descriptions:
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What is the first step in the repair of a bone fracture?
What is the first step in the repair of a bone fracture?
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Sex hormones do not affect growth modifications of the skeleton.
Sex hormones do not affect growth modifications of the skeleton.
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Name one vitamin that is essential for bone growth.
Name one vitamin that is essential for bone growth.
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What are osteoblasts primarily responsible for?
What are osteoblasts primarily responsible for?
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Osteocytes are immature bone cells derived from osteoclasts.
Osteocytes are immature bone cells derived from osteoclasts.
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What is the primary function of osteoclasts?
What is the primary function of osteoclasts?
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The process of _______ occurs when mineral salts are deposited in a framework of collagen fibers.
The process of _______ occurs when mineral salts are deposited in a framework of collagen fibers.
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What is a characteristic of compact bone?
What is a characteristic of compact bone?
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Match the type of bone with its characteristics:
Match the type of bone with its characteristics:
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Which hormone increases blood calcium ion levels?
Which hormone increases blood calcium ion levels?
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Spongy bone contains osteons.
Spongy bone contains osteons.
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Bone acts primarily as a storage reservoir for potassium ions (K+).
Bone acts primarily as a storage reservoir for potassium ions (K+).
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Bone is richly supplied with _______ to support its function.
Bone is richly supplied with _______ to support its function.
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What condition is characterized by a decrease in the amount and strength of bone tissue?
What condition is characterized by a decrease in the amount and strength of bone tissue?
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Bone remodeling is affected by mechanical stress; removal of mechanical stress leads to ________.
Bone remodeling is affected by mechanical stress; removal of mechanical stress leads to ________.
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Match the following disorders with their characteristics:
Match the following disorders with their characteristics:
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What role does calcitonin play in calcium homeostasis?
What role does calcitonin play in calcium homeostasis?
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Weight-bearing activities contribute to the weakening of bone.
Weight-bearing activities contribute to the weakening of bone.
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What are the two principal effects of aging on bone?
What are the two principal effects of aging on bone?
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Study Notes
The Skeletal System: The Bone Tissue
- Bone comprises multiple tissues, including bone, cartilage, dense connective tissue, epithelium, blood-forming tissues, adipose tissue, and nervous tissue.
- Each bone is categorized as an organ, collectively forming the skeletal system along with cartilages.
Functions of Bone and the Skeletal System
- Bones support soft tissues and provide muscle attachment sites, serving as the body's structure.
- Internal organs are protected by bony coverings.
- Bones facilitate movement by assisting skeletal muscles.
- Major minerals, especially calcium and phosphorus, are stored and released by bones to maintain mineral balance.
- Hemopoiesis, or blood cell formation, occurs in the red marrow of bones.
- Yellow marrow serves as a triglyceride storage site in adults.
Structure of Bone
- Long bones consist of several parts: the diaphysis (shaft), epiphyses (ends), and metaphyses (areas between).
- The epiphyseal plate is critical for bone elongation during growth.
- Hyaline cartilage at the ends minimizes friction and absorbs shock.
- The periosteum covers the bone, promoting growth and repair and anchoring ligaments and tendons.
- The marrow cavity within the diaphysis contains yellow marrow or adipose tissue.
Histology of Bone Tissue
- Osseous tissue consists of widely spaced cells and significant extracellular matrix.
- Four principal bone cell types:
- Osteoprogenitor cells develop into osteoblasts.
- Osteoblasts are responsible for bone formation.
- Osteocytes maintain mature bone tissue.
- Osteoclasts break down bone tissue.
- The bone matrix includes inorganic salts (like hydroxyapatite and calcium carbonate) and collagen fibers, which confer hardness and tensile strength.
- Bone regions are classified as compact (dense) or spongy (lightweight with open spaces for marrow).
Blood and Nerve Supply of Bone
- Bones receive a rich blood supply through various vessels.
- Endochondral ossification involves transforming a cartilage model into bone, with six stages:
- Cartilage development and growth.
- Formation of primary and secondary ossification centers.
- Development of a medullary cavity and articular cartilage.
- Bone growth in length occurs at the epiphyseal plate, which has zones for resting, proliferation, hypertrophy, and calcification.
Growth and Remodeling of Bone
- Appositional growth allows bone thickness increase via osteoblast activity in the periosteum.
- Bone remodeling is the continuous process of replacing old bone tissue with new tissue, influenced by factors like dietary intake and hormonal regulations.
- Acute hormonal signals are required for bone growth during childhood and major growth spurts.
Fracture and Repair of Bone
- A fracture represents any break in bone integrity.
- Fracture repair involves several stages, from clot formation to restoration of the bone structure.
- Common fracture types include open, comminuted, and stress fractures.
- Treatment requires realignment and immobilization to facilitate healing.
Bone’s Role in Calcium Homeostasis
- Bones act as the primary reservoir for calcium, regulating blood calcium levels through parathyroid hormone (PTH) and calcitonin.
- PTH increases blood calcium levels, while calcitonin decreases them.
Exercise and Bone Tissue
- Mechanical stress strengthens bone through increased mineral deposition and collagen production.
- Lack of stress leads to demineralization and reduced collagen.
- Weight-bearing exercises, like walking, promote bone mass retention.
Aging and Bone Tissue
- Aging primarily results in the loss of minerals (demineralization) and decreased protein synthesis, heightening fracture risk.
Disorders: Homeostatic Imbalances
- Bone scans serve as a diagnostic tool for identifying bone abnormalities.
- Osteoporosis involves decreased bone density and strength due to hormonal changes.
- Rickets and osteomalacia are conditions characterized by poor bone mineralization.
Medical Terminology
- Familiarity with medical terms related to skeletal tissue is essential for effective communication in the field.
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Description
Explore the intricacies of the skeletal system through this quiz focused on bone tissue and its various components. Test your knowledge on the functions of bone and how it supports the body. Ideal for students studying this essential aspect of human anatomy.