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Biology of Immortality: Telomeres and Telomerase

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3 Questions

What is the primary role of telomeres in cells?

To protect the ends of chromosomes

How does caloric restriction affect lifespan?

It can extend lifespan by approximately 30%

What is a potential risk of manipulating telomerase in the body?

It can cause cancer cells to achieve immortality

Study Notes

Telomeres and Cell Lifespan

  • Telomeres shorten with each cell division, leading to cell senescence and death.

Telomerase and Its Implications

  • Telomerase is an enzyme that can prevent telomere shortening and potentially extend cell life.
  • Cancer cells use telomerase to achieve immortality, highlighting the potential dangers of manipulating telomeres.
  • Further research into telomerase and its side effects is crucial for potential applications in extending lifespan.

Caloric Restriction and Longevity

  • Caloric restriction is a proven method for extending lifespan in various organisms.
  • Reducing calorie intake by 30% can increase lifespan by roughly 30%, regardless of species.
  • Extensive research supports the potential benefits of caloric restriction for longevity.

Importance of Research

  • Scientific research is essential for understanding the complex mechanisms of aging.
  • Exploring potential solutions for extending lifespan requires careful consideration of both benefits and risks associated with manipulating cellular processes to achieve immortality.

Explore the concept of immortality through the lens of telomeres and telomerase. Learn how telomeres shorten with cell division and the role of telomerase in preventing this process.

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