12 Questions
What is the primary function of ground substance in connective tissue?
To facilitate the exchange of molecules
What is the main component of the extracellular matrix responsible for its gel-like state?
Aggrecan aggregates
Which type of glycosaminoglycan is nonsulfated?
Hyaluronic acid
What is the origin of most connective tissues?
Mesoderm
What is the primary component of connective tissue fibers?
Proteins
What is the primary function of fibronectin in connective tissue?
To facilitate cell adhesion
What is the main component of connective tissue?
Cells and extracellular matrix
What is the function of aggrecan aggregates in the extracellular matrix?
To maintain the gel-like state of the extracellular matrix
What is the primary function of connective tissue in the body?
To provide structural support and aid in defense and protection
What is the origin of most connective tissues during embryonic development?
Mesoderm
What is the function of chondronectin in connective tissue?
To localize to cartilage
What is the function of elastic fibers in connective tissue?
To allow for flexibility and elasticity
Study Notes
Characteristics of Connective Tissue
- Forms a continuum with epithelial, muscle, and nervous tissue to maintain a functionally integrated body
- Most connective tissues originate from mesoderm, the middle germ layer of embryonic tissue
- Composed of cells and extracellular matrix consisting of ground substance and fibers
Functions of Connective Tissue
- Provides structural support
- Serves as a medium for exchange
- Aids in the defense and protection of the body
- Forms a site for storage of fat
Ground Substance
- Hydrated, amorphous material
- Composed of: • Glycosaminoglycans (sulfated and nonsulfated) • Proteoglycans (covalently linked to hyaluronic acid, forming aggrecan aggregates) • Adhesive glycoproteins (various types, including laminin, chondronectin, osteonectin, and fibronectin)
Fibers of Connective Tissue
- Elongated structures formed from proteins that polymerize after secretion from fibroblasts
- Three main types of fibers: • Collagen fibers • Reticular fibers • Elastic fibers
Characteristics of Connective Tissue
- Forms a continuum with epithelial, muscle, and nervous tissue to maintain a functionally integrated body
- Most connective tissues originate from mesoderm, the middle germ layer of embryonic tissue
- Composed of cells and extracellular matrix consisting of ground substance and fibers
Functions of Connective Tissue
- Provides structural support
- Serves as a medium for exchange
- Aids in the defense and protection of the body
- Forms a site for storage of fat
Ground Substance
- Hydrated, amorphous material
- Composed of: • Glycosaminoglycans (sulfated and nonsulfated) • Proteoglycans (covalently linked to hyaluronic acid, forming aggrecan aggregates) • Adhesive glycoproteins (various types, including laminin, chondronectin, osteonectin, and fibronectin)
Fibers of Connective Tissue
- Elongated structures formed from proteins that polymerize after secretion from fibroblasts
- Three main types of fibers: • Collagen fibers • Reticular fibers • Elastic fibers
Learn about the structure and function of connective tissue, including its composition, origin, and role in maintaining a functionally integrated body.
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