Bio - 2024 eksamen
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The main executive molecules in prokaryotic cells are:

  • Fats
  • Inorganic compounds
  • Nucleic acids
  • Proteins (correct)
  • The functions of DNA polymerase in DNA replication do not include:

  • Analysis of each nucleotide for error correction
  • Catalyzing the formation of a phosphodiester bond
  • Adding nucleotides to a new strand according to the rule of base complementarity
  • Initiation of replication (correct)
  • Defects of proteins directly involved in DNA repair and its regulation:

  • They accelerate the aging process
  • They increase susceptibility to cancer
  • All answers are correct (correct)
  • They cause a decrease in immunity
  • Chromosomes as individual structures are visible:

    <p>In the metaphase of cell division</p> Signup and view all the answers

    The human karyotype is described using inclusive symbols. These symbols include:

    <p>All answers are correct</p> Signup and view all the answers

    Organelles that are formed from bacteria absorbed by a eukaryotic proton-cell are:

    <p>Mitochondria</p> Signup and view all the answers

    The 46 XY karyotype corresponds to:

    <p>A healthy man</p> Signup and view all the answers

    The lack of mitochondria characterizes the cells of organisms that are called:

    <p>Anaerobic</p> Signup and view all the answers

    The primary structure of deoxyribonucleic acid (DNA) is called:

    <p>Linear arrangement of individual nucleotides in a DNA strand</p> Signup and view all the answers

    Which of the following cell organelles are surrounded by two membranes?

    <p>Cell nucleus, mitochondria</p> Signup and view all the answers

    Peripheral blood lymphocytes are used for cytogenetic tests because:

    <p>They are easy to download</p> Signup and view all the answers

    A property of homologous autosomal chromosomes in a normal human cell is that:

    <p>All answers are correct</p> Signup and view all the answers

    Gyrase is an enzyme that:

    <p>It attaches to the DNA strand before the replication fork</p> Signup and view all the answers

    The function of cholesterol in the cell membrane is:

    <p>Regulation of membrane properties such as stiffness and permeability</p> Signup and view all the answers

    The cellular structures that give cells their mechanical strength are:

    <p>Intermediate filaments</p> Signup and view all the answers

    Composition of the large ribosomal subunit in eukaryotes:

    <p>rRNA molecules: 28S, 5.8S, 5S</p> Signup and view all the answers

    Stem cells have the ability to self-renew because:

    <p>They can divide without differentiation</p> Signup and view all the answers

    Transition mutations involve:

    <p>Replacing adenine (A) with guanine (G)</p> Signup and view all the answers

    The histone that stabilizes the histone octamer is:

    <p>Histone H1 and exceptionally H5 in erythrocytes</p> Signup and view all the answers

    Polyacrylamide gel electrophoresis is used for:

    <p>Protein separation</p> Signup and view all the answers

    In humans, development in the female direction occurs in a case of:

    <p>All answers are correct</p> Signup and view all the answers

    The components of the cell nucleus do not include:

    <p>Golgi apparatus</p> Signup and view all the answers

    A protein made from the combination of peptide subunits is a protein with a:

    <p>Fourth-order structure</p> Signup and view all the answers

    Routine chromosome staining methods allow detection of:

    <p>Numerical chromosomal aberrations</p> Signup and view all the answers

    The function of ligase during DNA replication is:

    <p>Gluing Okazaki fragments together</p> Signup and view all the answers

    The process of RNA interference is:

    <p>Silencing gene expression</p> Signup and view all the answers

    Apoptotic bodies will not be found in the structure of:

    <p>Macrophages</p> Signup and view all the answers

    Ethyl alcohol added to a DNA solution causes:

    <p>DNA precipitation</p> Signup and view all the answers

    Regeneration may be classified as reproduction:

    <p>Asexual</p> Signup and view all the answers

    Glycolysis occurs in the:

    <p>Cytoplasm</p> Signup and view all the answers

    Epigenetic modifications that regulate gene expression include:

    <p>DNA methylation</p> Signup and view all the answers

    70% of the total mass of a cell is made up of:

    <p>Water molecules</p> Signup and view all the answers

    In which cell will smooth endoplasmic reticulum predominate?

    <p>In cells synthesizing non-protein organic products</p> Signup and view all the answers

    Lipophilic synthetic vectors that penetrate cells and thus transport exogenous DNA are:

    <p>Liposomes</p> Signup and view all the answers

    When the sodium-potassium pump in the cell stops working, the osmotic balance with the extracellular environment is disturbed, and the cell:

    <p>It cracks due to the inflow of water</p> Signup and view all the answers

    The concept of epigenetics refers to:

    <p>Changes in gene function or expression</p> Signup and view all the answers

    Small nuclear RNA (snRNA):

    <p>They function in the regulation of gene expression by participating in the splicing of the pre-mRNA molecule</p> Signup and view all the answers

    The action of products of different genes that complement each other is named:

    <p>Complementation</p> Signup and view all the answers

    Select the true statement about the mitochondrial genome:

    <p>The AUU codon in mitochondria is the translation initiation codon.</p> Signup and view all the answers

    The quaternary structure of proteins is:

    <p>Functional protein complexes</p> Signup and view all the answers

    Sequences that enhance transcription are called:

    <p>Enhancers</p> Signup and view all the answers

    Most often, chromosome structural aberrations are used to perform the test using:

    <p>Peripheral blood lymphocytes</p> Signup and view all the answers

    Stabilization of the quaternary structure of protein macromolecules is possible due to, among other:

    <p>Hydrogen bonds, disulfide bonds, hydrophobic and electrostatic interactions</p> Signup and view all the answers

    The cell membrane is a natural barrier between the cell's surroundings and its external environment and......

    <p>All of the above</p> Signup and view all the answers

    Select the correct statement about telomeres:

    <p>The presence of telomeres ensures that the length of genomes remains constant</p> Signup and view all the answers

    In the fields of molecular biology and genetics, a genome is:

    <p>All answers are correct</p> Signup and view all the answers

    Apoptosis is a form of programmed cell death that occurs in:

    <p>All answers are correct</p> Signup and view all the answers

    Necrosis is a form of cell injury which results in:

    <p>All answers are correct</p> Signup and view all the answers

    What process ends the mitotic division of each cell?

    <p>Cytokinesis</p> Signup and view all the answers

    The genetic information of a eukaryotic organism that enables proper replication includes:

    <p>In the DNA double helix</p> Signup and view all the answers

    The Endoplasmic Reticulum is:

    <p>A spatial system of single membranes dividing the cytoplasm into compartments with different metabolism</p> Signup and view all the answers

    Which of the following proteins is called the "guardian of the genome"?

    <p>P53</p> Signup and view all the answers

    Restriction enzymes can produce:

    <p>Sticky and blunt ends</p> Signup and view all the answers

    In the process of splicing the transcript, fragments called pre-mRNA are cut out:

    <p>Introns</p> Signup and view all the answers

    The expression product of the genome, which is a set of RNA molecules (including mRNA) encoding proteins, is referred to as:

    <p>Transcriptome</p> Signup and view all the answers

    Does translation and transcription occur during cell mitosis?

    <p>No, both processes are inhibited</p> Signup and view all the answers

    Heat shock proteins are produced in response to:

    <p>All answers are correct</p> Signup and view all the answers

    The Human Karyotype is described using inclusive symbols:

    <p>All answers are correct</p> Signup and view all the answers

    The primary structure of deoxyribonucleic acid is called

    <p>Linear arrangement of individual nucleotides in a DNA strand</p> Signup and view all the answers

    Small nuclear RNA:

    <p>They function in the regulation of gene expression by participating in the splicing of the pre-mRNA molecule</p> Signup and view all the answers

    Sequences that enhance transcription are:

    <p>Enhancers</p> Signup and view all the answers

    Most often chromosome structural aberrations are used to perform the test:

    <p>Peripheral blood lymphocytes</p> Signup and view all the answers

    Study Notes

    Prokaryotic Cells Executive Molecules

    • The main executive molecules in prokaryotic cells are proteins.

    DNA Polymerase Functions

    • DNA polymerase does not initiate DNA replication.
    • DNA polymerase functions include: analyzing each nucleotide for error correction, adding nucleotides to a new strand according to the rule of base complementarity, catalyzing the formation of a phosphodiester bond.

    DNA Repair Defects

    • Defects in DNA repair proteins increase cancer susceptibility, decrease immunity, and accelerate aging.

    Chromosome Visibility

    • Chromosomes are visible in metaphase of cell division.

    Human Karyotype Components

    • The human karyotype includes chromosome number, length, and identified irregularities.

    Organelles from Absorbed Bacteria

    • Mitochondria are organelles formed from bacteria absorbed by eukaryotic cells.

    Karyotype and Gender

    • A 46,XY karyotype indicates a healthy male.

    Mitochondria and Organisms

    • Organisms lacking mitochondria are anaerobic.

    Primary DNA Structure

    • The primary structure of DNA is the linear arrangement of nucleotides.

    Cell Organelles with Two Membranes

    • Cell nucleus and mitochondria are surrounded by two membranes.

    Lymphocytes for Cytogenetic Tests

    • Peripheral blood lymphocytes are used for cytogenetic tests because they are easy to obtain.

    Homologous Autosomal Chromosomes

    • Homologous autosomal chromosomes are paired, numbered 1-22, and have the same shape and length.

    Gyrase Enzyme Function

    • Gyrase attaches to the DNA strand before the replication fork.

    Cholesterol Role in Cell Membranes

    • Cholesterol regulates membrane properties like stiffness and permeability.

    Cell Mechanical Strength

    • Intermediate filaments provide mechanical strength to cells.

    Eukaryotic Ribosomal Subunit Composition

    • The large ribosomal subunit in eukaryotes contains rRNA molecules (28S, 5.8S, and 5S).

    Stem Cell Self-Renewal

    • Stem cells self-renew by dividing without differentiating.

    Transition Mutations

    • Transition mutations involve replacing one purine with another purine (e.g., A with G).

    Histone Stabilizing Histone Octamer

    • Histone H1, and exceptionally H5 in erythrocytes, stabilizes the histone octamer.

    Polyacrylamide Gel Electrophoresis Use

    • Polyacrylamide gel electrophoresis separates proteins.

    Female Development and Sex Chromosomes

    • Female development occurs with the absence of a Y chromosome or if a Y chromosome is present but lacks the SRY gene.

    Cell Nucleus Components

    • The cell nucleus does not contain the Golgi apparatus.

    Protein Structure Levels

    • A protein made from multiple peptide subunits has a quaternary structure.

    Chromosome Aberration Detection

    • Routine chromosome staining primarily detects numerical chromosomal aberrations.

    Ligase Role in DNA Replication

    • DNA ligase joins Okazaki fragments.

    RNA Interference

    • RNA interference silences gene expression.

    Apoptosis and Cell Components

    • Macrophages, not cell organelles, eliminate apoptotic bodies.

    DNA and Ethyl Alcohol

    • Ethyl alcohol precipitates DNA.

    Regeneration and Reproduction

    • Regeneration can be a form of asexual reproduction.

    Glycolysis Location

    • Glycolysis occurs in the cytoplasm.

    Epigenetic Modifications

    • DNA methylation is an epigenetic modification regulating gene expression.

    Cell Mass Composition

    • Water molecules constitute 70% of a cell’s mass.

    Smooth Endoplasmic Reticulum Predominance

    • Smooth endoplasmic reticulum predominates in cells synthesizing non-protein organic products.

    Synthetic DNA Vectors

    • Liposomes are lipophilic synthetic vectors that penetrate cells and transport exogenous DNA.

    Sodium-Potassium Pump and Osmotic Balance

    • A malfunctioning sodium-potassium pump disrupts osmotic balance, leading to water influx and cell lysis.

    Epigenetic Definition

    • Epigenetics concerns changes in gene function/expression.

    Small Nuclear RNA Function

    • Small nuclear RNA (snRNA) participates in pre-mRNA splicing.

    Gene Complementation

    • The synergistic action of the products from different genes is termed complementation.

    Mitochondrial Genome Codon

    • The AUU codon is the translation initiation codon in mitochondria.

    Protein Quaternary Structure

    • The quaternary structure of proteins describes functional protein complexes.

    Transcription Enhancers

    • Enhancers are DNA sequences that enhance transcription.

    Chromosome Aberration Testing

    • Peripheral blood lymphocytes are commonly used for chromosome structural aberration testing.

    Protein Quaternary Structure Stabilization

    • Quaternary protein structure stabilization involves hydrogen bonds, disulfide bonds, hydrophobic and electrostatic interactions.

    Cell Membrane Function

    • The cell membrane selectively exchanges substances, allows for cell responsiveness, and has a protective function.

    Telomere Function

    • Telomeres maintain constant genome length.

    Genome Definition

    • The genome encompasses all genetic information in an organism.

    Apoptosis Description

    • Apoptosis is a form of programmed cell death in multicellular organisms.

    Necrosis Description

    • Necrosis is premature cell death caused by external factors, often detrimental.

    Mitosis Termination

    • Cytokinesis ends mitotic cell division.

    Eukaryotic Replication Information

    • The DNA double helix holds the genetic information for eukaryotic replication.

    Endoplasmic Reticulum Structure and Function

    • The endoplasmic reticulum is a system of interconnected membranes dividing the cytoplasm into specialized compartments for different metabolic processes.

    P53 Function

    • P53 is a protein referred to as the "guardian of the genome," involved in genome stability.

    Restriction Enzyme Products

    • Restriction enzymes produce both sticky and blunt ends.

    Splicing Transcript Pre-mRNA Fragments

    • Introns are the pre-mRNA fragments removed during splicing.

    Transcriptome Definition

    • The transcriptome is the set of RNA molecules (including mRNA) encoding proteins.

    Transcription and Translation During Mitosis

    • Both transcription and translation are inhibited during cell mitosis.

    Heat Shock Proteins and Cell Responses

    • Heat shock proteins are induced in response to various cellular stressors.

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    Description

    This quiz covers key concepts related to prokaryotic cells, DNA structures, and their functions. It includes discussions on DNA polymerase, DNA repair mechanisms, and the characteristics of human karyotypes. Test your knowledge on cellular organelles and genetic information!

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