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What is a key characteristic of active transport mechanisms?
What is a key characteristic of active transport mechanisms?
In primary active transport, the energy derives directly from which source?
In primary active transport, the energy derives directly from which source?
What process uses the electrochemical gradient established by primary active transport?
What process uses the electrochemical gradient established by primary active transport?
Which example is NOT associated with primary active transport?
Which example is NOT associated with primary active transport?
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What is the general function of carrier proteins in the context of active transport?
What is the general function of carrier proteins in the context of active transport?
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What is the primary fluid found within all body cells?
What is the primary fluid found within all body cells?
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Which of the following fluids surrounds the cells and serves as an exchange medium?
Which of the following fluids surrounds the cells and serves as an exchange medium?
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How many liters of plasma are there in a body with 70 kg total body water?
How many liters of plasma are there in a body with 70 kg total body water?
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What significant charge characterizes the proteins found in intracellular fluid?
What significant charge characterizes the proteins found in intracellular fluid?
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What is the role of homeostasis in the body?
What is the role of homeostasis in the body?
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Which component of extracellular fluid is responsible for the transport of nutrients and waste products?
Which component of extracellular fluid is responsible for the transport of nutrients and waste products?
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What is the main ion found in high concentration within intracellular fluid?
What is the main ion found in high concentration within intracellular fluid?
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What distinguishes extracellular fluid from intracellular fluid?
What distinguishes extracellular fluid from intracellular fluid?
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Which process is primarily responsible for maintaining osmotic balance in the body?
Which process is primarily responsible for maintaining osmotic balance in the body?
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What is the main factor contributing to the high fluid levels in the intracellular space compared to extracellular fluid?
What is the main factor contributing to the high fluid levels in the intracellular space compared to extracellular fluid?
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Which type of transport mechanism requires a special membrane protein?
Which type of transport mechanism requires a special membrane protein?
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What is the primary characteristic that distinguishes active transport from passive transport mechanisms?
What is the primary characteristic that distinguishes active transport from passive transport mechanisms?
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What is the approximate resting membrane potential of a cell?
What is the approximate resting membrane potential of a cell?
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Which transport mechanism moves substances in the same direction as sodium ions?
Which transport mechanism moves substances in the same direction as sodium ions?
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What is a common feature of facilitated diffusion?
What is a common feature of facilitated diffusion?
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What is NOT a property of passive transport mechanisms?
What is NOT a property of passive transport mechanisms?
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Which physiological process relies on changes in resting potential for signaling?
Which physiological process relies on changes in resting potential for signaling?
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How does active transport typically move substances?
How does active transport typically move substances?
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What defines amphipathic molecules?
What defines amphipathic molecules?
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What process is essential for maintaining osmotic balance in cells?
What process is essential for maintaining osmotic balance in cells?
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What is the primary direction of water movement during osmosis?
What is the primary direction of water movement during osmosis?
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What occurs to a cell in a hypotonic solution?
What occurs to a cell in a hypotonic solution?
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What is the osmotic pressure of human cells equivalent to?
What is the osmotic pressure of human cells equivalent to?
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What happens to cells in a hypertonic solution?
What happens to cells in a hypertonic solution?
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Why is an isotonic NaCl solution preferred over an isoosmotic solution of penetrating solutes like urea for restoring blood volume?
Why is an isotonic NaCl solution preferred over an isoosmotic solution of penetrating solutes like urea for restoring blood volume?
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In which scenario would osmosis not occur?
In which scenario would osmosis not occur?
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What is the effect of an isotonic environment on a cell?
What is the effect of an isotonic environment on a cell?
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What is the primary goal of homeostasis?
What is the primary goal of homeostasis?
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What role does osmosis play at the tissue level?
What role does osmosis play at the tissue level?
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Which factor is NOT homeostatically regulated?
Which factor is NOT homeostatically regulated?
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Which component of the homeostatic control mechanism is responsible for monitoring internal conditions?
Which component of the homeostatic control mechanism is responsible for monitoring internal conditions?
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What is the function of the effector in the homeostatic control mechanisms?
What is the function of the effector in the homeostatic control mechanisms?
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Homeostasis relies primarily on which type of feedback mechanism?
Homeostasis relies primarily on which type of feedback mechanism?
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What happens when there is a failure to compensate for homeostatic imbalances?
What happens when there is a failure to compensate for homeostatic imbalances?
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Which of the following best describes the relationship between homeostasis and the external environment?
Which of the following best describes the relationship between homeostasis and the external environment?
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Which of the following is an example of a factor that homeostasis regulates?
Which of the following is an example of a factor that homeostasis regulates?
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In the context of homeostasis, what does the term 'set point' refer to?
In the context of homeostasis, what does the term 'set point' refer to?
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What might be a physiological consequence of failing to regulate body temperature?
What might be a physiological consequence of failing to regulate body temperature?
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Study Notes
Osmosis
- Movement of water through a selectively permeable membrane from regions of higher concentration to regions of lower concentration.
- Water moves from high concentration of water to lower concentration of water (and from lower concentration of solutes to higher concentration of solutes).
- Important at cellular level, causing cells to shrink or swell.
- Important at tissue level, osmosis occurs through epithelial cells in the GIT and renal system. It also occurs through capillary walls.
Osmotic Pressure
- The osmotic pressure inside human cells is equal to the concentration of a 0.9% solution of sodium chloride (99.1 g water + 0.9 g NaCl).
- 0.9% NaCl solution is called “normal or physiologic saline”.
- Hypotonic: OP in extracellular fluid is less than OP intracellular fluid, causing water to enter the cell.
- Hypertonic: OP in extracellular fluid is greater than OP intracellular fluid, causing the cell to lose water.
- Isotonic: OP in extracellular fluid is equal to OP intracellular fluid, resulting in hydrostatic equilibrium.
Active Transport
- Carrier molecules transport substances across a membrane from regions of lower concentration to regions of higher concentration.
- Examples: glucose, amino acids, sodium ions, potassium, calcium, and Hydrogen ions.
- It is carrier-mediated and requires energy to move “uphill” against an electrical or pressure gradient.
Primary Active Transport
- Energy comes directly from the breakdown of ATP or some other high-energy phosphate compound.
- Examples:
- Na+/K+ pump found in all cells.
- Ca++ active transport in cell membrane and inside the cell.
- Active transport of H+ found in gastric glands of the stomach and distal and collecting tubules of the kidney.
- H+/K+ pump (proton pump at the stomach).
Secondary Active Transport
- Energy is derived secondarily from energy stored in the form of ionic concentration differences between the two sides of the membrane, created by primary active transport.
- Examples:
- Na+/glucose co-transport.
- Na+/amino acid co-transport.
Body Fluids
-
Extracellular fluid (ECF): fluid environment in which the cells live (fluid outside the cells), containing ions, O2, nutrients, and waste products.
- Includes:
- Plasma (inside blood cells)
- Interstitial fluid (around the cells)
- Includes:
- Intracellular fluid (ICF): fluid contained within all body cells, high in K+ and low in Na+. It contains protein with a negative charge.
- ICF:ECF ratio: 2:1, meaning that ICF accounts for 2/3 and ECF for 1/3 of total body water.
Homeostasis
- Maintenance of a relatively constant/stable internal environment (extracellular fluids).
- Maintaining a dynamic steady state in the internal environment.
- The internal environment remains relatively constant despite changes in the external environment.
- Stable does not mean rigid, values can vary within a narrow limit (normal physiological range).
- Essential for survival and function of all cells.
Factors Homeostatically Regulated
- Concentration of nutrients (e.g., glucose, O2, CO2, and waste products).
- Concentration of water, salt, and other electrolytes.
- pH.
- Blood volume and pressure.
- Body temperature.
Homeostatic Control Mechanisms
- Three components:
- Receptor: provides information about the stimuli.
- Control Center: tells what a particular value should be (called the set point).
- Effector: elicits responses that change conditions in the internal environment.
Negative Feedback Loops
- Sensor: monitors internal conditions, detects changes.
- Integrating Center (Controller): receives and integrates information.
- Effector: responds to changes, activity of effectors results in return of the condition to normal levels.
Movements Into and Out of the Cell
Property | Simple Diffusion | Facilitated Diffusion | Active Transport |
---|---|---|---|
Requires special membrane protein | No | Yes | Yes |
Highly selective | No | Yes | Yes |
Uphill transport | No | No | Yes |
Requires energy | No | No | Yes |
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Description
Explore the fundamental concepts of osmosis and osmotic pressure in this quiz. Understand how water movement influences cellular behavior and the impact of different saline solutions on human cells. Test your knowledge of hypotonic, hypertonic, and isotonic environments.