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Questions and Answers
What key feature distinguishes lipids from other major biological molecules?
What key feature distinguishes lipids from other major biological molecules?
Which of the following statements accurately describes the relationship between cellulose and starch?
Which of the following statements accurately describes the relationship between cellulose and starch?
Why are fats hydrophobic?
Why are fats hydrophobic?
What is the significance of the double bonds in unsaturated fatty acids?
What is the significance of the double bonds in unsaturated fatty acids?
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How does the structure of cellulose contribute to its function as a structural component in plant cell walls?
How does the structure of cellulose contribute to its function as a structural component in plant cell walls?
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How do herbivores, lacking the necessary enzymes to digest cellulose, obtain energy from plant material?
How do herbivores, lacking the necessary enzymes to digest cellulose, obtain energy from plant material?
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What is the primary function of chitin in arthropods?
What is the primary function of chitin in arthropods?
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Which of the following is NOT a key component of a fat molecule?
Which of the following is NOT a key component of a fat molecule?
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What is the main difference between saturated and unsaturated fatty acids?
What is the main difference between saturated and unsaturated fatty acids?
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What is the role of dehydration reactions in the formation of fats?
What is the role of dehydration reactions in the formation of fats?
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What is true regarding hydrogenated vegetable oil?
What is true regarding hydrogenated vegetable oil?
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What are the components of a triglyceride molecule?
What are the components of a triglyceride molecule?
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Which category encompasses all others listed?
Which category encompasses all others listed?
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Which of the following can the enzyme amylase break down?
Which of the following can the enzyme amylase break down?
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What would be the molecular formula for a polymer made by linking ten glucose molecules together by dehydration reactions?
What would be the molecular formula for a polymer made by linking ten glucose molecules together by dehydration reactions?
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Why is butter solid at room temperature, while vegetable oil is a liquid?
Why is butter solid at room temperature, while vegetable oil is a liquid?
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What type of carbohydrate is sucrose?
What type of carbohydrate is sucrose?
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Which of the following statements is true of the carbohydrate glucose?
Which of the following statements is true of the carbohydrate glucose?
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How are triglycerides formed?
How are triglycerides formed?
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Which of the following is a characteristic of lipids?
Which of the following is a characteristic of lipids?
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Which of the following occurs when hydrogen is reacted with vegetable oil?
Which of the following occurs when hydrogen is reacted with vegetable oil?
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What type of bond is primarily found in saturated fats?
What type of bond is primarily found in saturated fats?
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Which carbohydrate is commonly known as blood sugar?
Which carbohydrate is commonly known as blood sugar?
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Study Notes
Bioprocess Fundamentals - CENV 2200
- Course instructor: Dr. Ali Al Jibouri, P.Eng.
- Office: SW01-1580
- Email: [email protected]
The Molecules of Life
- Organic molecules are the most important large molecules found in living things.
- These include carbohydrates, proteins, nucleic acids, and lipids.
Macromolecules
- Macromolecules are large molecules composed of thousands of covalently connected atoms.
- Most macromolecules are polymers.
- Polymers are long molecules consisting of many similar building blocks (monomers).
Polymers
- Monomers form larger molecules through condensation reactions called dehydration reactions.
- One molecule loses hydrogen, the other loses OH.
- Polymers are disassembled to monomers by hydrolysis.
- Hydrolysis is the reverse of dehydration reaction.
Polymers (continued)
- Each cell has thousands of different kinds of macromolecules.
- Macromolecules vary among cells of an organism, vary more within a species, and vary even more between species.
- An immense variety of polymers can be built from a small set of monomers.
Carbohydrates
- Carbohydrates include sugars and the polymers of sugars.
- Simple carbohydrates are monosaccharides.
- Monosaccharides are single sugars.
- Carbohydrate macromolecules are polysaccharides.
- Polysaccharides are polymers composed of many sugar building blocks.
Monosaccharides
- Monosaccharides have molecular formulas that are usually multiples of CH2O.
- Glucose is the most common monosaccharide.
- Monosaccharides are classified by the location of the carbonyl group and by the number of carbons in the carbon skeleton.
- Monosaccharides serve as a major fuel for cells and as raw material for building molecules.
- In aqueous solutions, monosaccharides form rings, the most stable form.
Disaccharides
- Disaccharides are formed when a dehydration reaction joins two monosaccharides.
- The covalent bond formed is called a glycosidic bond.
- Examples include: Lactose (glucose and galactose), Maltose (glucose and glucose), Sucrose (glucose and fructose).
Polysaccharides
- Polysaccharides, the polymers of sugars, have storage and structural roles.
- The structure and function of a polysaccharide are determined by its sugar monomers and the positions of the glycosidic linkages.
Storage Polysaccharides
- Starch is a storage polysaccharide of plants, consisting entirely of glucose monomers.
- Two types of starch are amylose and amylopectin.
- Plants store surplus starch as granules within chloroplasts and other plastids.
- Glycogen is a storage polysaccharide in animals.
- Humans and other vertebrates store glycogen in liver and muscle cells.
Structural Polysaccharides
- Cellulose is a major component of the tough wall of plant cells.
- Cellulose is a polymer of glucose, but the glycosidic linkages differ.
- The difference is based on two ring forms for glucose: alpha (a) and beta (β).
- Polymers with a-glucose are helical, while polymers with β-glucose are straight.
- In straight structures H atoms on one strand can bond with OH groups on other strands.
- Parallel cellulose molecules are grouped into microfibrils, strong building material for plants.
- Chitin is another structural polysaccharide found in the exoskeleton of arthropods and cell walls of many fungi.
Lipids
- Lipids are the only class of large biological molecules that do not form polymers.
- The unifying feature of lipids is having little or no affinity for water.
- Lipids are hydrophobic because they consist mostly of hydrocarbons which form nonpolar covalent bonds.
- The most biologically important lipids are fats, phospholipids, and steroids.
Fats
- Fats are constructed from glycerol and fatty acids.
- Glycerol is a three-carbon alcohol with a hydroxyl group attached to each carbon.
- A fatty acid consists of a carboxyl group attached to a long carbon skeleton.
- In a fat, three fatty acids are joined to glycerol by an ester linkage, creating a triacylglycerol, or triglyceride.
- Fatty acids vary in length (number of carbons) and in the number and locations of double bonds.
- Saturated fatty acids have the maximum number of hydrogen atoms possible and no double bonds.
- Unsaturated fatty acids have one or more double bonds.
- The major function of fats is energy storage.
Phospholipids
- In a phospholipid, two fatty acids and a phosphate group are attached to glycerol.
- The two fatty acid tails are hydrophobic, but the phosphate group and its attachments form a hydrophilic head.
- When phospholipids are added to water, they self-assemble into a bilayer.
- The structure of phospholipids results in a bilayer arrangement found in cell membranes.
- Phospholipids are the major component of all cell membranes.
Steroids
- Steroids are lipids characterized by a carbon skeleton consisting of four fused rings.
- Cholesterol, an important steroid, is a component in animal cell membranes.
Proteins
- Proteins account for more than 50% of the dry mass of most cells.
- Protein functions include structural support, storage, transport, cellular communications, movement, and defense against foreign substances.
- Proteins consist of a backbone of an amino group (-NH2) and a carboxyl group (-C(=O)OH).
- Twenty different amino acids are involved in the structure of a variety of proteins which have various functions.
Polypeptides
- Polypeptides are polymers of amino acids.
- A protein is a biologically functional molecule composed of one or more polypeptides.
- Amino acids are linked by peptide bonds.
Amino Acid Monomers
- An amino acid is an organic molecule with both an amino group and a carboxyl group.
- Amino acids differ in their properties due to differing side chains (R groups).
- Proteins are constructed from the same set of 20 amino acids, linked in unbranched polymers.
Protein Structure and Function
- A functional protein consists of one or more polypeptides twisted, folded, and coiled into a unique shape.
- The sequence of amino acids determines a protein's three-dimensional conformation.
- A protein's conformation determines its function.
- Ribbon models and space-filling models can depict a protein's conformation.
Protein Structure - Primary
- The amino acid sequence in a protein.
- Determined by inherited genetic information
Protein Structure - Secondary
- Coils and folds found in most proteins
- Result from hydrogen bonds between repeating constituents of polypeptide backbone.
- Include a-helix and ẞ pleated sheet.
Protein Structure - Tertiary
- Overall shape of a polypeptide, resulting from interactions between side chains (R groups) of various amino acids.
- Includes hydrogen bonds, ionic bonds, hydrophobic interactions, and disulfide linkages.
Protein Structure - Quaternary
- Results when a protein consists of multiple polypeptide chains.
Protein Folding
- It is hard to predict a protein's conformation from its primary structure.
- Most proteins probably go through several states on their way to a stable conformation.
- Chaperonins are protein molecules that assist the proper folding of other proteins.
Protein Denaturation
- Denaturation is loss of conformation which occurs in protein structure due to physical or chemical conditions (pH, salt concentration, temperature).
- Denatured proteins are biologically inactive.
Nucleic Acids
- Nucleic acids are polymers called polynucleotides.
- Each polynucleotide is made of monomers called nucleotides.
- Each nucleotide consists of a nitrogenous base, a pentose sugar, and a phosphate group.
- DNA provides directions for its own replication.
- DNA directs synthesis of messenger RNA (mRNA) in which mRNA controls protein synthesis.
- Protein synthesis occurs in ribosomes.
DNA double helix
- A DNA molecule has two polynucleotides spiralling around an imaginary axis, forming a double helix.
- In the DNA double helix, the two backbones run in opposite 5' to 3' directions, antiparallel.
- One DNA molecule includes many genes.
- The nitrogenous bases in DNA form hydrogen bonds in a complementary fashion. A always with T, and G always with C
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Description
This quiz explores the characteristics and functions of lipids and carbohydrates in biological systems. It covers key concepts such as the structure of fats, the differences between saturated and unsaturated fatty acids, and the significance of polysaccharides like cellulose and chitin. Test your understanding of these essential biomolecules and their roles in organisms.