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Questions and Answers
What is the primary mechanism through which errors are minimized during DNA replication?
What is the primary mechanism through which errors are minimized during DNA replication?
Which type of mutation involves the exchange of one nucleotide for another?
Which type of mutation involves the exchange of one nucleotide for another?
How do repair proteins contribute to DNA integrity after replication?
How do repair proteins contribute to DNA integrity after replication?
What effect does a single nucleotide change in DNA have on protein structure?
What effect does a single nucleotide change in DNA have on protein structure?
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What type of mutation removal occurs when one nucleotide is deleted from a DNA sequence?
What type of mutation removal occurs when one nucleotide is deleted from a DNA sequence?
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What is the role of complementary base-pairing in DNA replication?
What is the role of complementary base-pairing in DNA replication?
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Which two nitrogenous bases pair together in the DNA double helix?
Which two nitrogenous bases pair together in the DNA double helix?
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What structure forms the 'sides of the ladder' in a DNA molecule?
What structure forms the 'sides of the ladder' in a DNA molecule?
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How do different alleles of a gene primarily differ from each other?
How do different alleles of a gene primarily differ from each other?
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Which of the following accurately describes the structure of DNA?
Which of the following accurately describes the structure of DNA?
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What causes mutations in DNA?
What causes mutations in DNA?
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Which type of mutation involves a substitution of one nucleotide for another?
Which type of mutation involves a substitution of one nucleotide for another?
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What is the relationship between genes and proteins?
What is the relationship between genes and proteins?
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What is the primary function of DNA?
What is the primary function of DNA?
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Which of the following describes the correct sequence of structural organization from smallest to largest?
Which of the following describes the correct sequence of structural organization from smallest to largest?
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What describes the process of DNA replication?
What describes the process of DNA replication?
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Which statement accurately reflects the semi-conservative nature of DNA replication?
Which statement accurately reflects the semi-conservative nature of DNA replication?
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How do slight differences in alleles affect the resulting protein product?
How do slight differences in alleles affect the resulting protein product?
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What is meant by complementary base pairing in DNA?
What is meant by complementary base pairing in DNA?
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During which phase of the cell cycle does DNA replication occur?
During which phase of the cell cycle does DNA replication occur?
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What feature characterizes alleles for a particular gene?
What feature characterizes alleles for a particular gene?
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Study Notes
Chapter 9: What Genes Are
- DNA is deoxyribonucleic acid, our genetic blueprint, which codes for aspects of who we are.
- DNA contains genes that code for proteins.
- Alleles are different versions of a gene.
- Nucleotides are the building blocks of nucleic acids.
- DNA is a huge, double-stranded molecule made of nucleotides.
Nucleotides
- Each nucleotide has three parts: a sugar (deoxyribose), a phosphate group, and a nitrogenous base.
- Nitrogenous bases in DNA include Adenine (A), Thymine (T), Cytosine (C), and Guanine (G).
- A pairs with T, and C pairs with G.
DNA Structure
- The two strands of DNA are connected by bonds linking the nucleotide base pairs.
- The DNA double helix is a twisted, ladder-like structure.
- Nucleotides are linked together by covalent bonds to form one strand.
- The two strands are held together by hydrogen bonds between the complementary bases.
DNA Sequencing
- The sequence of bases on a DNA strand varies among species, subtypes within a species, and individuals within a species.
Gene Structure and Function
- All genes are composed of just four nucleotides.
- Information in genes is carried by the order of nucleotides.
- Variations in the nucleotide order in different genes lead to different proteins and gene products.
DNA Replication
- DNA replication is the duplication of a DNA molecule.
- This happens during the S phase (synthesis phase) of interphase in the cell cycle.
- DNA replication is semiconservative, meaning each new DNA molecule contains one strand from the original molecule and one newly synthesized strand.
- The process begins at specific locations called "origins of replication".
- DNA polymerase is the key enzyme involved.
Mutation Corrections
- DNA polymerase proofreading is a system used to correct mistakes during replication.
- Repair proteins correct the vast majority of mistakes in newly replicated DNA.
Mutations
- A mutation is a change to the sequence of nucleotides in an organism's DNA.
- Point mutations occur when a single base is altered in a sequence.
- Types of point mutations include substitutions (one nucleotide is exchanged for another), insertions (one nucleotide is added), and deletions (one nucleotide is removed).
- Sickle cell disease is an example of a point mutation affecting hemoglobin.
Review: Chromosome Structure
- Chromosomes consist of a DNA strand wrapped up and organized into a compact structure.
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Description
Explore the fundamentals of genetics in Chapter 9, focusing on the structure of DNA and its key components like nucleotides and genes. Understand the roles of alleles and how base pairings contribute to the genetic blueprint of living organisms. This chapter delves into the DNA double helix and its importance in genetics.