Biology Chapter 8 DNA to Proteins Quiz
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Questions and Answers

What is the main difference between the four nucleotides that make up DNA?

bases

Who figured out the three-dimensional structure of DNA by using a model of metal and wood?

Watson & Crick

In humans, where does DNA replication take place?

nucleus

What is the function of the enzyme DNA polymerase during replication?

<p>bind nucleotides together</p> Signup and view all the answers

What does messenger RNA do during transcription?

<p>It delivers DNA's instructions for making proteins</p> Signup and view all the answers

How often does transcription take place to produce all the protein that a cell needs?

<p>on a gene segment over and over again</p> Signup and view all the answers

What does the central dogma state?

<p>DNA to RNA to proteins</p> Signup and view all the answers

What are exons?

<p>sections of messenger RNA that are spliced together during processing</p> Signup and view all the answers

What binds with the repressor to activate the lac operon in bacteria?

<p>lactose</p> Signup and view all the answers

What is a mutagen?

<p>an agent in the environment that can change DNA</p> Signup and view all the answers

Where must a mutation occur if it is to be passed to offspring?

<p>in a germ cell</p> Signup and view all the answers

What is the complementary DNA sequence to CCGTACT?

<p>GGCATGA</p> Signup and view all the answers

What would you use to figure out the sequence on the other strand of a DNA double helix?

<p>base pairing rules</p> Signup and view all the answers

What is the complementary RNA sequence to the DNA sequence TAGAGTC?

<p>AUCUCAG</p> Signup and view all the answers

When does DNA replication occur?

<p>once in every cell cycle</p> Signup and view all the answers

What does Crick's central dogma summarize?

<p>replication, transcription, and translation</p> Signup and view all the answers

How many amino acids are coded for in the mRNA sequence CGAUACAGUAGC?

<p>4</p> Signup and view all the answers

When does mRNA processing take place?

<p>after transcription</p> Signup and view all the answers

What are introns?

<p>nucleotide sequences that are removed during mRNA processing</p> Signup and view all the answers

How does the ribosome interact with mRNA and tRNA during translation?

<p>small ribosome binds to mRNA, attracting tRNA with methionine to start codon</p> Signup and view all the answers

What happens when the ribosome encounters a stop codon?

<p>The peptide strand would be released &amp; ribosome would fall apart</p> Signup and view all the answers

Where does translation occur?

<p>cytoplasm</p> Signup and view all the answers

What is the function of an amino acid?

<p>will form peptide bond with another amino acid, forming a protein</p> Signup and view all the answers

What is the start codon and the nucleotide sequence for the corresponding anticodon?

<p>AUG; UAC</p> Signup and view all the answers

How does a frameshift mutation (insertion) affect the way the mRNA is read?

<p>The reading frame is thrown off because all the nucleotides are shifted to the right.</p> Signup and view all the answers

How would a frameshift mutation (insertion) affect the structure of the resulting protein?

<p>Resulting protein could have different amino acids, different shape/different protein</p> Signup and view all the answers

If a frameshift mutation occurred in a body cell, would the offspring be affected?

<p>False (B)</p> Signup and view all the answers

What are the 3 ways that RNA differs from DNA?

<p>Ribose instead of deoxyribose, single strand instead of double strand, U instead of T</p> Signup and view all the answers

Name the 3 stop codons.

<p>UAA, UAG, UGA</p> Signup and view all the answers

Flashcards

DNA Bases

Adenine, thymine, cytosine, and guanine are the four nitrogenous bases that make up DNA.

DNA Structure Discovery

The three-dimensional structure of DNA was discovered by Watson and Crick using a model made of metal and wood.

DNA Replication Location

In the nucleus of human cells, DNA is replicated, creating an identical copy.

DNA Polymerase

DNA polymerase is the enzyme responsible for joining nucleotides together during DNA replication.

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DNA Replication Frequency

DNA replication occurs once per cell cycle, ensuring each new cell receives a complete set of genetic information.

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mRNA Function

Messenger RNA (mRNA) carries genetic instructions from DNA to the ribosomes, where proteins are synthesized.

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Transcription Repetition

Transcription occurs repeatedly on a gene segment to produce enough mRNA for the required protein levels.

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mRNA Processing

mRNA processing involves splicing exons together, which code for protein sequences, and removing introns, non-coding regions.

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Central Dogma

The central dogma of molecular biology explains the flow of genetic information from DNA to RNA to proteins.

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Crick's Central Dogma

Crick's summary of the central dogma encompasses DNA replication, transcription, and translation.

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Start Codon

The start codon, AUG, initiates protein synthesis.

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Anticodon for AUG

The anticodon UAC is complementary to the start codon AUG, allowing tRNA to bind to the mRNA.

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Triplet Code

mRNA codons are read in groups of three, known as the triplet code.

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Codon Example

For example, the sequence CGAUACAGUAGC codes for four amino acids.

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Translation Location

Translation takes place in the cytoplasm, where the ribosome binds to mRNA and attracts tRNA carrying methionine to the start codon.

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Mutagens

Mutagens are environmental factors that can alter DNA sequences.

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Heritable Mutations

Mutations that occur in germ cells, which give rise to eggs or sperm, can be inherited by offspring.

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Frameshift Mutation

A frameshift mutation (insertion) shifts the reading frame of the codons, potentially altering the amino acid sequence and structure of the resulting protein.

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Body Cell Mutations

Frameshift mutations in body cells do not affect offspring because they are not passed to gametes.

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RNA vs. DNA

RNA differs from DNA in its sugar, strand configuration, and nitrogenous base.

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RNA Sugar

RNA contains ribose sugar, while DNA contains deoxyribose.

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RNA Strand

RNA is single-stranded, compared to DNA's double-stranded structure.

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RNA Base

RNA uses uracil (U) instead of thymine (T) like in DNA.

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Stop Codons

There are three stop codons (UAA, UAG, and UGA) that signal the termination of protein synthesis.

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Stop Codon Function

Stop codons instruct the ribosome to halt translation, releasing the newly synthesized protein.

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Study Notes

DNA Structure and Function

  • Four nucleotides in DNA differ by their bases: adenine, thymine, cytosine, and guanine.
  • Watson and Crick discovered the three-dimensional structure of DNA using a model made of metal and wood.

DNA Replication

  • In humans, DNA replication occurs in the nucleus.
  • DNA polymerase is the enzyme that binds nucleotides together during replication.
  • Replication happens once in every cell cycle.

Transcription and mRNA Processing

  • Messenger RNA (mRNA) carries DNA instructions to synthesize proteins.
  • Transcription occurs repeatedly on a gene segment to produce adequate protein levels.
  • mRNA processing involves splicing exons together and removing introns.

Central Dogma of Molecular Biology

  • The central dogma outlines the information flow from DNA to RNA to proteins.
  • Crick's summary encompasses replication, transcription, and translation.

Codons and Translational Mechanics

  • The start codon is AUG, with the corresponding anticodon UAC.
  • mRNA codons are read in groups of three, known as the triplet code; for example, the sequence CGAUACAGUAGC codes for 4 amino acids.
  • Translation takes place in the cytoplasm, where the ribosome binds to mRNA and attracts tRNA carrying methionine to the start codon.

Mutations and Their Effects

  • Mutagens are environmental agents that can alter DNA.
  • Mutations that can be inherited must occur in germ cells.
  • A frameshift mutation (insertion) shifts the reading frame, potentially altering the resultant protein's amino acid sequence and structure.
  • Frameshift mutations in body cells do not affect offspring since they are not passed to gametes.

RNA vs. DNA

  • RNA differs from DNA in three significant ways:
    • RNA contains ribose, while DNA contains deoxyribose.
    • RNA is single-stranded compared to DNA’s double-stranded structure.
    • RNA uses uracil (U) instead of thymine (T).

Stop Codons

  • There are three stop codons: UAA, UAG, and UGA, which signal the termination of protein synthesis.

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Test your knowledge on Chapter 8 from DNA to Proteins with these interactive flashcards. Explore essential concepts including nucleotide differences, DNA structure, and replication processes. Perfect for revision and understanding key biological principles.

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