Questions and Answers
A nucleotide is made up of which of the following components? (Select all that apply)
Where is the phosphate group of a nucleotide found?
5' carbon
What is the difference between the 5-carbon sugars of DNA and RNA?
RNA has 2 hydroxyl groups at the 2' and 3' carbons
Which nucleic acid contains thymine?
Signup and view all the answers
Which nucleic acids contain a phosphate group?
Signup and view all the answers
Which nucleic acid contains ribose?
Signup and view all the answers
Which nucleic acid contains uracil?
Signup and view all the answers
Which nucleic acid contains deoxyribose?
Signup and view all the answers
Which nucleic acid is normally double stranded?
Signup and view all the answers
Which nucleic acid is normally single stranded?
Signup and view all the answers
Why are DNA sugars called deoxyribose?
Signup and view all the answers
What are the components of a nucleotide?
Signup and view all the answers
What does DNA stand for?
Signup and view all the answers
What is the main purpose of DNA?
Signup and view all the answers
What is the sugar in DNA?
Signup and view all the answers
What are the subunits that make up DNA?
Signup and view all the answers
What is a purine?
Signup and view all the answers
What are the two purines?
Signup and view all the answers
Who made the structure of DNA?
Signup and view all the answers
How did Rosalind Franklin contribute to determining the structure of DNA?
Signup and view all the answers
What types of bonds hold DNA together?
Signup and view all the answers
What makes up the backbone of DNA?
Signup and view all the answers
What was Phoebus Levene's contribution to the discovery of DNA?
Signup and view all the answers
What was Fredrick Griffith's contribution to the discovery of DNA?
Signup and view all the answers
What was Avery, MacLeod, and McCarty's contribution to the discovery of DNA?
Signup and view all the answers
What was Alfred Hershey and Martha Chase's contribution to the discovery of DNA?
Signup and view all the answers
What was Erwin Chargaff's contribution to the discovery of DNA?
Signup and view all the answers
What was Maurice Wilkin's contribution to the discovery of DNA?
Signup and view all the answers
What was Watson and Crick's contribution to the discovery of DNA?
Signup and view all the answers
Study Notes
Nucleotide Structure
- A nucleotide consists of a phosphate group, a pentose sugar, and a nitrogenous base.
- The phosphate group is attached to the 5' carbon of the sugar.
Differences Between DNA and RNA
- DNA contains deoxyribose sugar; RNA contains ribose sugar with hydroxyl groups at the 2' and 3' carbons.
- DNA includes the nitrogenous base thymine (T); RNA includes uracil (U).
- DNA is typically double-stranded, while RNA is usually single-stranded.
Sugar Characteristics
- Deoxyribose lacks a hydroxyl group on the 2' carbon, whereas ribose has a hydroxyl group on the 2' carbon.
Base Characteristics
- Thymine (T) and cytosine (C) are pyrimidines; adenine (A) and guanine (G) are purines.
- Adenine (A) forms 2 hydrogen bonds with thymine (T) and 2 with uracil (U); cytosine (C) and guanine (G) form 3 hydrogen bonds with each other.
DNA/RNA Processes
- Replication is the process of DNA making a copy of itself.
- Transcription refers to RNA synthesis from a DNA template.
- Translation describes the synthesis of proteins based on RNA instructions.
Key Discoveries in DNA Research
- Phoebus Levene identified nucleotide components: base, sugar, and phosphate group.
- Frederick Griffith demonstrated heredity principles using Streptococcus pneumonia.
- Avery, MacLeod, and McCarty showed that DNA acts as the transforming agent in heredity.
- Hershey and Chase confirmed DNA injection by T4 bacteriophage into host bacteria.
- Erwin Chargaff discovered base pair equivalency ratios (A=T, C=G).
- Rosalind Franklin obtained high-quality X-ray diffraction images of DNA's structure.
- Watson and Crick are credited with building the model of DNA's double helix structure.
Structural Components of DNA
- DNA stands for deoxyribonucleic acid.
- The primary function of DNA is to store genetic information in chromatids.
- The backbone of DNA is made up of sugar and phosphate groups.
- Hydrogen bonds hold the base pairs of DNA together.
Summary of DNA Composition
- DNA comprises the nitrogenous bases adenine (A), thymine (T), cytosine (C), and guanine (G).
- The subunits of DNA include a nitrogenous base, pentose sugar, and a phosphate group.
- Purines are double-ringed nitrogenous bases, specifically adenine (A) and guanine (G).
Historical Contributions
- Watson and Crick are recognized for confirming DNA’s double-helix structure.
- Rosalind Franklin contributed by providing X-ray images aiding in the understanding of DNA structure.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz consists of flashcards focusing on the structure and components of nucleotides. It covers key concepts such as the phosphate group, sugar differences in DNA and RNA, and the overall makeup of nucleotides. Perfect for students studying molecular biology or biochemistry!
