Podcast
Questions and Answers
Which of the following elements is NOT mentioned as a component of living organisms?
Which of the following elements is NOT mentioned as a component of living organisms?
What is the general term for the chemical activities that occur within cells?
What is the general term for the chemical activities that occur within cells?
What is the percentage of fresh weight of cells that water makes up?
What is the percentage of fresh weight of cells that water makes up?
Why is water considered essential for life?
Why is water considered essential for life?
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What type of bonds are formed between water molecules?
What type of bonds are formed between water molecules?
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What is the role of water in transporting substances?
What is the role of water in transporting substances?
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What is the term used to describe the large molecules that carry genetic information?
What is the term used to describe the large molecules that carry genetic information?
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Why do evolutionists believe that life evolved in water?
Why do evolutionists believe that life evolved in water?
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What is the primary function of cellulose and chitin in living organisms?
What is the primary function of cellulose and chitin in living organisms?
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What is characteristic of lipids in comparison to carbohydrates?
What is characteristic of lipids in comparison to carbohydrates?
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What is the primary difference between fats and oils?
What is the primary difference between fats and oils?
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Why are fats a good source of energy?
Why are fats a good source of energy?
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What is the function of phospholipids and steroids in living organisms?
What is the function of phospholipids and steroids in living organisms?
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Why are lipids insoluble in water?
Why are lipids insoluble in water?
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What is the significance of fatty acids in lipids?
What is the significance of fatty acids in lipids?
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Why are fats and oils good insulators?
Why are fats and oils good insulators?
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What type of specificity is shown by enzymes that can distinguish one enantiomer from another?
What type of specificity is shown by enzymes that can distinguish one enantiomer from another?
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What is the term for the non-protein prosthetic group that binds to an enzyme to make it active?
What is the term for the non-protein prosthetic group that binds to an enzyme to make it active?
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Which of the following enzymes is an example of a protease that selectively hydrolyse peptide bonds?
Which of the following enzymes is an example of a protease that selectively hydrolyse peptide bonds?
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What is the role of coenzymes in biochemical reactions?
What is the role of coenzymes in biochemical reactions?
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What is the term for the active enzyme that consists of the polypeptide portion and the non-protein prosthetic group?
What is the term for the active enzyme that consists of the polypeptide portion and the non-protein prosthetic group?
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Which vitamin is not associated with a coenzyme?
Which vitamin is not associated with a coenzyme?
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What is the effect of inhibitors on enzymes?
What is the effect of inhibitors on enzymes?
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What is the term for the enzyme that lacks the non-protein prosthetic group?
What is the term for the enzyme that lacks the non-protein prosthetic group?
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What is the primary function of catabolic reactions in a cell?
What is the primary function of catabolic reactions in a cell?
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What type of organisms use sunlight or chemical energy to build up their required macromolecules?
What type of organisms use sunlight or chemical energy to build up their required macromolecules?
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Why do metabolic reactions involve a series of steps?
Why do metabolic reactions involve a series of steps?
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What is the term for reactions that build up complex molecules from simpler ones?
What is the term for reactions that build up complex molecules from simpler ones?
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What is the purpose of catabolic reactions in heterotrophs?
What is the purpose of catabolic reactions in heterotrophs?
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Why do anabolic reactions tend to be endothermic?
Why do anabolic reactions tend to be endothermic?
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What is the term for the breakdown of complex materials into simpler ones?
What is the term for the breakdown of complex materials into simpler ones?
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What is the purpose of coupling anabolic and catabolic reactions in biological systems?
What is the purpose of coupling anabolic and catabolic reactions in biological systems?
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What is the primary role of the pentose phosphate pathway?
What is the primary role of the pentose phosphate pathway?
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What is the reduced form of NADP+ produced in the pentose phosphate pathway?
What is the reduced form of NADP+ produced in the pentose phosphate pathway?
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What is the precursor for the synthesis of nucleotides produced in the pentose phosphate pathway?
What is the precursor for the synthesis of nucleotides produced in the pentose phosphate pathway?
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Where does the pentose phosphate pathway take place in plants?
Where does the pentose phosphate pathway take place in plants?
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What is the name of the pathway that is also known as the pentose phosphate pathway?
What is the name of the pathway that is also known as the pentose phosphate pathway?
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Which tissues have high levels of PPP enzymes?
Which tissues have high levels of PPP enzymes?
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How many molecules of NADP+ are reduced to NADPH in the oxidative stage of the pentose phosphate pathway?
How many molecules of NADP+ are reduced to NADPH in the oxidative stage of the pentose phosphate pathway?
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What is the starting molecule in the oxidative stage of the pentose phosphate pathway?
What is the starting molecule in the oxidative stage of the pentose phosphate pathway?
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Study Notes
Biologically Important Molecules
- Living organisms are made up of a limited number of atoms, including carbon, hydrogen, oxygen, nitrogen, sulfur, and phosphorus, and ions like Na+, Mg2+, Cl-, K+, and Ca2+.
- These elements combine to form molecules, which are the building blocks of life, varying in size from simple molecules like carbon dioxide and water to macromolecules like proteins and nucleic acids.
Water
- Water is the most abundant small molecule, making up 60-95% of the fresh weight of all cells/organisms.
- It is a vital constituent of living cells, forms part of the extra-cellular fluid of multicellular organisms, and serves as an environment for unicellular organisms.
- Water is the medium in which the majority of metabolic reactions take place, a reactant in some metabolic reactions, and a solvent for a wide variety of chemicals found in cells, including wastes.
- Its unique combination of properties makes it essential to the continuance of life.
Lipids
- Lipids are a group of compounds with no general formula, sharing the property of being insoluble in water due to the lack of polar groups.
- They contain carbon, hydrogen, and oxygen, but with a lower proportion of oxygen than in carbohydrates.
- Some lipids also contain phosphorus.
- Fats and oils are familiar lipids, formed from fatty acids and glycerol.
- Fats are solid at room temperature, found in animals, and contain mainly saturated fatty acids.
- Oils are liquid at room temperature, found in plants, and contain mainly unsaturated fatty acids.
Enzymes and Cofactors
- Some enzymes need an additional non-protein prosthetic group to function, called the cofactor.
- The polypeptide portion of the enzyme is called the apoenzyme, and the combination of the two is the active enzyme, called the holoenzyme.
- Cofactors may be metal ions, organic compounds, or organometallic compounds.
- Coenzymes are low-molecular-weight organic molecules that serve as carriers of electrons or chemical groups.
Inhibitors and Metabolism
- Inhibitors are chemicals that can bind to enzymes and either eliminate or drastically reduce their catalytic ability.
- Metabolism can be divided into catabolism and anabolism.
- Catabolic reactions break down complex materials, producing raw materials for building new cellular materials and providing energy for these processes.
- Anabolic reactions build complex molecules from simpler molecules, requiring energy.
The Pentose Phosphate Pathway
- The pentose phosphate pathway (PPP) is an alternative pathway for the oxidation of glucose, also known as the Warburg-Dickens pathway or the phosphogluconate pathway.
- Its primary role is anabolic, generating NADPH and pentoses (5-carbon sugars), as well as ribose 5-phosphate, a precursor for the synthesis of nucleotides.
- The PPP is most active in tissues involved in cholesterol and fatty acid syntheses, requiring abundant NADPH.
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Description
This quiz covers the introduction to biologically important molecules, exploring the atoms and ions that form the building blocks of life.