Biology Cancer and Cell Cycle Quiz
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Questions and Answers

A change in any gene is known as a ______

mutation

Cancerous cells divide repeatedly and uncontrollably, forming a ______

tumour

Carcinogens are any agents that may cause ______

cancer

Malignant tumours can interfere with the normal functioning of the ______ in which they have started to grow

<p>organ</p> Signup and view all the answers

The spreading of cancers through the body is known as ______

<p>metastasis</p> Signup and view all the answers

The tightly coiled combination of DNA and proteins is called ______.

<p>chromatin</p> Signup and view all the answers

The main proteins associated with chromosomes, known for organizing and condensing DNA, are called ______.

<p>histones</p> Signup and view all the answers

The ends of chromosomes are protected by repetitive sequences of DNA known as ______.

<p>telomeres</p> Signup and view all the answers

The enzyme responsible for adding additional bases to telomeres is called ______.

<p>telomerase</p> Signup and view all the answers

Interphase consists of three phases: G1, S, and ______.

<p>G2</p> Signup and view all the answers

During the S phase of the cell cycle, ______ is replicated.

<p>DNA</p> Signup and view all the answers

In the G1 phase, the cell synthesizes proteins including ______ for growth.

<p>enzymes</p> Signup and view all the answers

The movement from one phase of the cell cycle to another is triggered by chemical signals known as ______.

<p>cyclins</p> Signup and view all the answers

Mitosis produces two genetically identical daughter ______.

<p>nuclei</p> Signup and view all the answers

During ______, the chromatin condenses and becomes visible as sister chromatids.

<p>prophase</p> Signup and view all the answers

Centrosomes reach opposite ______ during metaphase.

<p>poles</p> Signup and view all the answers

In anaphase, sister chromatids are pulled to opposite ______.

<p>poles</p> Signup and view all the answers

During telophase, the ______ reforms around the chromosomes.

<p>nuclear membrane</p> Signup and view all the answers

Mitosis is important for the growth of multicellular organisms and the ______ of damaged cells.

<p>replacement</p> Signup and view all the answers

______ reproduction occurs when new individuals are produced by a single parent.

<p>Asexual</p> Signup and view all the answers

Roots tips of garlic or ______ are commonly used to study mitosis.

<p>onion</p> Signup and view all the answers

A stem cell can divide an unlimited number of times by ______.

<p>mitosis</p> Signup and view all the answers

Totipotent stem cells can differentiate into any cell type found in an ______.

<p>embryo</p> Signup and view all the answers

Pluripotent stem cells can differentiate into any cell type found in an embryo but not into extra-______ cells.

<p>embryonic</p> Signup and view all the answers

Multipotent adult stem cells can produce a limited range of ______ types.

<p>cell</p> Signup and view all the answers

Stem cells found in ______ marrow are multipotent and can differentiate into blood cells.

<p>bone</p> Signup and view all the answers

While many adult cells lose their ability to divide, ______ stem cells remain capable of division.

<p>adult</p> Signup and view all the answers

Changes in genes that control cell division can lead to the formation of a ______.

<p>tumour</p> Signup and view all the answers

Cells undergoing ______ can be seen during specific phases like prophase, metaphase, and anaphase.

<p>mitosis</p> Signup and view all the answers

Flashcards

Chromosome

A thread-like structure made of DNA carrying genetic information in the form of genes.

Gene

A sequence of nucleotides forming part of a DNA molecule.

Histone

A positively charged protein that helps in organizing and condensing DNA in eukaryotic cells.

Chromatin

The tightly coiled combination of DNA and proteins (histones) found in chromosomes.

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Sister Chromatids

Two identical copies of a chromosome joined together at the centromere before cell division.

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Telomeres

Non-coding DNA sequences located at the ends of chromosomes.

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Telomerase

The enzyme that adds additional bases to telomeres during DNA replication, preventing loss of genetic information.

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What is mitosis?

A process where a single nucleus divides into two identical daughter nuclei. It occurs during the growth, repair and asexual reproduction of multicellular organisms.

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What happens in prophase?

The first stage of mitosis where the genetic material condenses into visible chromosomes, the nuclear membrane breaks down, and the spindle fibres begin to form.

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What happens during metaphase?

The stage of mitosis where chromosomes line up at the middle of the cell, attached to spindle fibres at their centromere.

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What happens in anaphase?

The stage of mitosis where the centromeres of the chromosomes split, and sister chromatids are pulled towards opposite poles of the cell by shortening spindle fibres.

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What happens in telophase?

The final stage of mitosis where chromosomes decondense, the nuclear membrane reforms around the two sets of chromosomes, and nucleoli reappear.

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What is cytokinesis?

The division of the cytoplasm and organelles between the two newly formed daughter cells after mitosis.

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What is asexual reproduction?

The process of creating new individuals from a single parent. Offspring are genetically identical to the parent.

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What are meristems in plants?

Specific regions in plants where growth occurs, particularly in root tips where cells undergo mitosis.

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Stem Cell

A cell that can divide (by mitosis) an unlimited number of times, producing new cells that can remain stem cells or differentiate into specialized cells.

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What is a mutation?

A change in the genetic code of a cell, which can lead to uncontrolled cell division and the development of cancer.

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Differentiation

The process by which a stem cell develops into a specialized cell, gaining specific functions and structures.

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What is a tumor?

A mass of abnormal cells that forms when mutated cells divide uncontrollably.

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Totipotent Stem Cell

Stem cells that can differentiate into any cell type found in an embryo, including extra-embryonic cells (cells that make up the placenta).

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What is a carcinogen?

Any substance or agent that increases the risk of developing cancer, such as UV radiation, tobacco smoke, or certain chemicals.

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Pluripotent Stem Cell

Stem cells that can differentiate into any cell type found in an embryo but cannot form extra-embryonic cells.

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What is a benign tumor?

A tumor that is non-cancerous and does not invade surrounding tissues. It usually does not spread to other parts of the body.

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What is a malignant tumor?

A tumor that is cancerous and can spread to other parts of the body, invading and destroying healthy tissues. It is also called a 'malignant tumor'.

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Multipotent Stem Cell

Adult stem cells that can only differentiate into a limited number of cell types within their specific tissue or organ.

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Cancer Formation

A process where changes occur in the genes that control cell division, leading to uncontrolled cell growth and the development of a tumor.

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Prophase

The first stage of mitosis, where chromosomes condense and become visible, the nuclear envelope breaks down, and the spindle fibers start to form.

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Metaphase

The stage of mitosis where chromosomes align at the center of the cell on the metaphase plate, attached to spindle fibers from opposite poles of the cell.

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Study Notes

Replication and Division of Nuclei and Cells

  • A chromosome is a thread-like structure of DNA that carries genetic information (genes).
  • Chromosomes are made of a long, condensed DNA molecule associated with proteins called histones. These histones help organize and condense the DNA to fit into the nucleus.
  • The DNA and proteins are called chromatin, which is what chromatids, and chromosomes are made of.
  • Chromosomes contain two genetically identical sister chromatids joined at a point called the centromere.
  • Telomeres are regions of non-coding DNA at the ends of chromosomes. They are made of repeated nucleotide sequences.
  • Telomeres play a crucial role in preventing the loss of genes during DNA replication.
  • Telomerase is an enzyme that adds bases at the ends of chromosomes to maintain telomere length.
  • The shortening of telomeres over successive cell divisions helps determine the lifespan of cells.

The Cell Cycle

  • The cell cycle is the regulated series of events that occur between cell divisions.
  • The length of the cell cycle varies depending on environmental conditions, cell type, and the organism.
  • The cell cycle is driven by chemical signals, called cyclins.
  • Interphase is the period between cell divisions and is divided into three phases: G1, S, and G2.
  • The G1 phase involves protein synthesis and cell growth.
  • The S phase involves DNA replication.
  • The G2 phase involves further cell growth, organelle division, and preparation for division.

Mitosis

  • Mitosis is the process of nuclear division that produces two genetically identical daughter nuclei, identical to the parent nucleus.
  • Cell growth stops during mitosis.
  • Mitosis is divided into four phases: prophase, metaphase, anaphase, and telophase.
  • During prophase, chromatin condenses into chromosomes, the nuclear membrane breaks down, and spindle fibers form.
  • In metaphase, chromosomes align at the cell's equator.
  • During anaphase, sister chromatids separate and are pulled to opposite poles of the cell.
  • Lastly, in telophase chromosomes decondense, the nuclear envelope reforms, and the nucleolus reappears, and spindle fibres break down.
  • Cytokinesis is the division of the cytoplasm to form two separate daughter cells.
  • Mitosis is essential for growth, development, repair, and asexual reproduction in multicellular organisms.

Observing Mitosis

  • Mitosis can be observed in the root tip meristems of plants.
  • Root tip meristems are regions of actively dividing cells.
  • A suitable stain, like orcein, is used to visualize the chromosomes.
  • Cells undergoing mitosis can be observed and analyzed under the microscope.

Role of Stem Cells

  • Stem cells are undifferentiated cells that can divide (by mitosis) and differentiate into specialized cells.
  • Stem cells have the potential to remain a stem cell or develop into various specialized cell types.
  • Stem cells can be classified based on their potency (ability to differentiate): totipotent, pluripotent, and multipotent.
  • Totipotent stem cells can differentiate into any cell type, including extra-embryonic cells.
  • Pluripotent stem cells can differentiate into any cell type within the embryo but not extra-embryonic cells.
  • Multipotent stem cells can differentiate into a limited range of cell types.

Formation of Tumours

  • Tumours are irregular masses of cells that form due to uncontrolled cell division (mitosis).
  • Mutations in genes that control cell division (mitosis) can lead to cancer.
  • Cancerous cells may not be destroyed by the immune system.
  • Carcinogens are substances that can cause cancer, such as UV light, tar, and X-rays.
  • Malignant tumors can spread through the body (metastasis).
  • Benign tumors do not spread from their original site.

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The Mitotic Cell Cycle PDF

Description

Test your knowledge about cancer, cell division, and the cell cycle with this quiz. Explore essential concepts such as mutations, carcinogens, tumor types, and the phases of interphase. Perfect for biology students looking to enhance their understanding of these critical topics.

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