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Questions and Answers
What is the main product of aerobic cellular respiration along with thermal energy?
What is the main product of aerobic cellular respiration along with thermal energy?
Why do larger, multicellular animals require special organ systems for gas exchange?
Why do larger, multicellular animals require special organ systems for gas exchange?
Which process describes the diffusion of oxygen into body cells?
Which process describes the diffusion of oxygen into body cells?
What energy currency do cells generate through the process of aerobic cellular respiration?
What energy currency do cells generate through the process of aerobic cellular respiration?
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What happens to ATP when it releases energy for cellular processes?
What happens to ATP when it releases energy for cellular processes?
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What is the primary purpose of a circulatory system in multicellular organisms?
What is the primary purpose of a circulatory system in multicellular organisms?
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Which of the following best describes a closed circulatory system?
Which of the following best describes a closed circulatory system?
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In which circuit does blood travel from the heart to the lungs for oxygenation?
In which circuit does blood travel from the heart to the lungs for oxygenation?
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What physiological function is NOT performed by the circulatory system?
What physiological function is NOT performed by the circulatory system?
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Which statement accurately describes hemolymph in an open circulatory system?
Which statement accurately describes hemolymph in an open circulatory system?
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What is the primary function of hemoglobin in red blood cells?
What is the primary function of hemoglobin in red blood cells?
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What type of blood cells are responsible for fighting infections?
What type of blood cells are responsible for fighting infections?
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Which component of blood has the highest water content?
Which component of blood has the highest water content?
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What occurs during vasodilation in arterioles?
What occurs during vasodilation in arterioles?
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Which of the following statements about veins is false?
Which of the following statements about veins is false?
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How does the intercellular matrix of blood help maintain osmotic pressure?
How does the intercellular matrix of blood help maintain osmotic pressure?
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What is the role of precapillary sphincter muscles?
What is the role of precapillary sphincter muscles?
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Which blood component is primarily involved in preventing blood clotting?
Which blood component is primarily involved in preventing blood clotting?
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What condition can result from weakened vein valves as people age?
What condition can result from weakened vein valves as people age?
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How does elasticity in artery walls affect blood flow?
How does elasticity in artery walls affect blood flow?
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What is the normal range for diastolic blood pressure?
What is the normal range for diastolic blood pressure?
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Which of the following is not a common symptom of low blood pressure?
Which of the following is not a common symptom of low blood pressure?
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What initiates the heartbeat in the heart's conduction system?
What initiates the heartbeat in the heart's conduction system?
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What is the primary consequence of untreated high blood pressure?
What is the primary consequence of untreated high blood pressure?
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Which chamber of the heart pumps oxygenated blood to the body?
Which chamber of the heart pumps oxygenated blood to the body?
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Which lifestyle factor is NOT associated with increased risk for high blood pressure?
Which lifestyle factor is NOT associated with increased risk for high blood pressure?
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What term describes the relaxation phase of the cardiac cycle?
What term describes the relaxation phase of the cardiac cycle?
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Which blood vessels supply oxygen and nutrients to the heart muscle itself?
Which blood vessels supply oxygen and nutrients to the heart muscle itself?
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What is the primary purpose of heart valves?
What is the primary purpose of heart valves?
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How does prolonged high blood pressure affect the arteries?
How does prolonged high blood pressure affect the arteries?
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Which waveform on an electrocardiogram represents ventricular depolarization?
Which waveform on an electrocardiogram represents ventricular depolarization?
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Which condition may result from untreated high blood pressure affecting the kidneys?
Which condition may result from untreated high blood pressure affecting the kidneys?
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What happens during the 'lub' sound of the heartbeat?
What happens during the 'lub' sound of the heartbeat?
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Which factor does NOT contribute to the risk of developing varicose veins?
Which factor does NOT contribute to the risk of developing varicose veins?
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What is the primary role of the respiratory membrane in the alveoli?
What is the primary role of the respiratory membrane in the alveoli?
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Which structural feature of the human respiratory system assists in protecting the lungs from foreign matter?
Which structural feature of the human respiratory system assists in protecting the lungs from foreign matter?
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How does the partial pressure of oxygen in the alveoli compare to the surrounding air?
How does the partial pressure of oxygen in the alveoli compare to the surrounding air?
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What percentage of oxygen is typically found in the atmosphere?
What percentage of oxygen is typically found in the atmosphere?
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What role does hemoglobin play in oxygen transport in the blood?
What role does hemoglobin play in oxygen transport in the blood?
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During which phase of ventilation do the external intercostal muscles contract?
During which phase of ventilation do the external intercostal muscles contract?
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What happens to the pressure in the lungs during expiration?
What happens to the pressure in the lungs during expiration?
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What is the primary method by which carbon dioxide is transported in the bloodstream?
What is the primary method by which carbon dioxide is transported in the bloodstream?
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What causes altitude sickness when climbing to high altitudes?
What causes altitude sickness when climbing to high altitudes?
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What is the vital capacity of the lungs?
What is the vital capacity of the lungs?
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What triggers an increase in breathing rate due to changes in blood chemistry?
What triggers an increase in breathing rate due to changes in blood chemistry?
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What is the role of erythropoietin (EPO) during reduced oxygen supply?
What is the role of erythropoietin (EPO) during reduced oxygen supply?
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What is the typical lifespan of a red blood cell?
What is the typical lifespan of a red blood cell?
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What is the main consequence of decreasing oxygen supply in altitude conditions?
What is the main consequence of decreasing oxygen supply in altitude conditions?
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Study Notes
Aerobic Cellular Respiration
- Cells require oxygen to survive and obtain energy from food. This process is called aerobic cellular respiration.
- Glucose and oxygen react to form carbon dioxide and water, releasing energy.
- Approximately 64% of the energy released is thermal energy, and 36% is stored in ATP (adenosine triphosphate).
- The ATP molecule is comprised of ADP(adenosine diphosphate), phosphate and energy. ADP + P + Energy → ATP
- Cells use ATP for various processes, including growth, movement, and building new molecules, through ATP → ADP + P + Energy.
Gas Exchange and Ventilation
- Gas exchange is the diffusion of oxygen into and carbon dioxide out of body cells.
- In simple organisms, oxygen diffuses directly through cell membranes.
- Multicellular organisms have specialized organ systems (e.g., lungs) for gas exchange.
- Gas exchange occurs in both lungs and cells:
- Lungs: Oxygen diffuses from air to the bloodstream, then to cells.
- Cells: Oxygen diffuses from blood into tissue fluid, then into cells, while Carbon Dioxide diffuses from cells to tissue fluid to blood then to lungs.
- Ventilation is the movement of oxygen-rich air into and carbon dioxide-rich air out of the lungs.
Respiratory Structures
- The human respiratory system features thin, permeable membranes for diffusion, a large surface area for gas exchange, a good blood supply, and a respiratory membrane within the lungs to carry oxygen-rich air.
- Lungs are enclosed within the thoracic cavity to protect the respiratory structures, they consist of a respiratory membrane with a large surface area and good blood supply.
- Air enters through the nose and mouth, warmed and moistened in nasal passages.
- Nasal passages filter and trap dust and airborne particles.
- The pharynx directs air to the trachea which is a semi-rigid tube of soft tissue with c-shaped cartilage bands maintaining a consistent open pathway.
- Trachea is lined with mucus-producing cells with cilia that further protect the lungs. Cilia sweep trapped materials upward for expulsion.
- Bronchi branch into bronchioles, which lead to alveoli - clusters of tiny sacs.
- Each alveolus is approximately 0.1-0.2 micrometres in diameter, and there are about 150 million alveoli in each lung.
- If all alveoli were spread out, they would cover a tennis court.
Gas Exchange in the Alveoli
- Alveoli are saturated with moisture, and air within them is a 37 degrees celsius temperature and saturated with water.
- Oxygen dissolves in liquid to diffuse across the respiratory membrane.
- The respiratory membrane is incredibly thin (one cell thick), making the distance for gas exchange very short.
Partial Pressures
- Air pressure varies with altitude (lower at higher altitudes); partial pressure reflects that of individual gases.
- At sea level, atmospheric pressure is 101.3 kPa. Oxygen comprises ~20.9% of air; Carbon Dioxide comprises ~0.0391%.
- Partial pressure of oxygen (PO2) and carbon dioxide (PCO2) are calculated proportionally from the amount in the overall air in the atmosphere.
- PO2 in alveoli is somewhat lower than surrounding air because of residual air and stale air that remains in the alveoli.
- PO2 in alveoli is greater than in capillaries, thus supporting diffusion to the bloodstream.
Oxygen Transport and Diffusion
- Oxygen diffuses from alveoli into plasma (the liquid component of blood) due to the pressure gradient.
- Hemoglobin is an iron-containing protein in red blood cells that binds to oxygen to form oxyhemoglobin.
- Nearly all oxygen is transported bound to hemoglobin (98.5%), with a small amount dissolved in plasma. Hemoglobin increases oxygen carrying capacity of blood 70x..
- Blood with hemoglobin carries ~20 mL oxygen per 100 mL blood;
- At tissues, oxygen diffuses into body cells. PO2 in the veins is still greater than 0; blood will always contain some oxygen.
Carbon Dioxide Transport and Diffusion
- Carbon dioxide (a by-product of cellular respiration) diffuses from tissues into the bloodstream due to a pressure gradient (tissue PCO2 is higher than blood PCO2).
- Carbon dioxide transport:
- 7% dissolved in plasma
- 20% bound to hemoglobin (carbaminohemoglobin)
- 73% converted to bicarbonate ions in plasma. Hydrogen ions increase acidity to trigger breathing. Hemoglobin carries hydrogen ions to avoid significant blood pH drops.
- In the lungs, CO2 diffuses from blood plasma to the air in alveoli. Bicarbonate and Hydrogen ions re-form CO2 and water in the lungs.
Altitude
- Atmospheric pressure decreases with altitude.
- Oxygen partial pressure decreases at higher altitudes (despite a constant percentage), limiting oxygen supply to the body.
- Reduced oxygen supply can cause altitude sickness.
- The body adapts to low oxygen by increasing red blood cell production (stimulated by erythropoietin (EPO)).
- Synthetic EPO is banned in competitive sports. Athletes train at high altitude to raise red blood cell counts.
Mechanism of Ventilation
-
Inspiration:
- External intercostal muscles contract, expanding rib cage.
- Diaphragm contracts and flattens, increasing thoracic cavity volume.
- Lung pressure decreases, causing air to enter.
-
Expiration:
- External intercostal muscles relax, shrinking rib cage.
- Diaphragm relaxes and curves upward, decreasing thoracic cavity volume.
- Lung pressure increases, forcing air out.
Lung Capacity
- Total Lung Capacity: Maximum volume of air in one breath.
- Tidal Volume: Normal/involuntary breath volume.
- Inspiratory Reserve Volume: Air forcibly inhaled after normal breathing.
- Expiratory Reserve Volume: Air forcibly exhaled after normal breathing.
- Residual Volume: Air remaining in lungs after forced exhalation, preventing collapse.
- Vital Capacity: Maximum air exhaled.
Other Topics
- Other topics discussed include: circulation, blood composition, blood vessels, blood pressure, and the cardiac cycle.
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Description
This quiz covers the essential processes of aerobic cellular respiration and gas exchange. Learn how cells utilize oxygen and glucose to produce energy and how gas exchange occurs in simple versus multicellular organisms. Test your understanding of how these processes contribute to cellular functions and overall metabolism.