Biology 1050 Final Exam Review (2023FA)
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Questions and Answers

The sequence of amino acids in a protein is referred to as its primary structure.

True (A)

Regardless of the amino acid to be bound to a tRNA molecule, all tRNA molecules use the same sequence at their 3' end to serve as the amino acid attachment site.

True (A)

Which is a function of the signal-recognition particle (SRP)?

  • The SRP binds to the SRP receptor on the rough endoplasmic reticulum. (correct)
  • The SRP speeds up translation.
  • The SRP binds to sugars added to proteins in the Golgi apparatus.
  • The SRP direct proteins to the nuclear pores of the nuclear envelope.

Structurally and functionally related groups of proteins are referred to as:

<p>Families (A)</p> Signup and view all the answers

Which one of the statements about translation in eukaryotes is correct?

<p>An initiation complex recognizes a 5' cap structure and scans for the first AUG triplet. (A)</p> Signup and view all the answers

Some enzymes are translated in the cytosol but remain inactive until they are phosphorylated by another enzyme, a kinase. Once they are phosphorylated, these enzymes become active. The phosphorylation of the enzyme would be considered a posttranslational modification.

<p>True (A)</p> Signup and view all the answers

There is approximately the same number of protein families as there are folding domains.

<p>True (A)</p> Signup and view all the answers

The tRNA that binds the start codon has the sequence ______ at its ______.

<p>5'-UAC-3', amino acid attachment site</p> Signup and view all the answers

Flashcards

Primary protein structure

The sequence of amino acids in a protein.

tRNA amino acid attachment site

Specific 3' end sequence on all tRNA molecules.

Signal-recognition particle (SRP) function

Directs proteins to the endoplasmic reticulum.

Protein families

Structurally and functionally related proteins.

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Eukaryotic translation initiation

mRNA 5' cap is recognized; scans for AUG.

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Posttranslational modification

Changes to a protein after translation.

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Protein families vs. folding domains

Number of protein families is not the same as folding domains.

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tRNA start codon

tRNA with 5'-UAC-3' anticodon.

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Primary protein structure example

Sequence of amino acids in insulin.

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tRNA - amino acid binding

tRNA molecule binds to a corresponding amino acid.

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SRP function specifics

Binds to the signal sequence of a nascent protein.

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Protein families - example

Hemoglobin and myoglobin are related protein families.

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Eukaryotic translation - mRNA processing

mRNA processing happens before translation.

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Post-translational enzyme activation

Inactive enzymes become active through phosphorylation.

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Protein folding domains

Structurally and functionally related groups of proteins.

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tRNA start codon sequence

tRNA with the anticodon 5'-UAC-3' for the start codon AUG.

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mRNA 5' cap role

Guides translation initiation.

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What are Protein families?

Related proteins in structure and function.

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Study Notes

Biology 1050 Final Exam (2023FA)

  • The sequence of amino acids in a protein is called its primary structure.
  • All tRNA molecules use the same 3' end as the amino acid attachment site, regardless of the amino acid.
  • The signal-recognition particle (SRP) directs proteins to the rough endoplasmic reticulum.
  • Structurally and functionally related proteins are called families.

Translation in Eukaryotes

  • An initiation complex recognizes the 5' cap structure and scans for the first AUG triplet.
  • Translation continues until the ribosome reaches the end of the mRNA.
  • There is an untranslated region at the 3' end of mRNA.

Post-translational Modification

  • Some enzymes are translated in the cytosol and remain inactive until they are phosphorylated by a kinase.
  • Phosphorylation of an enzyme is a post-translational modification.

Protein Families and Folding Domains

  • There are approximately the same number of protein families as folding domains.

tRNA Sequence

  • The tRNA that binds the start codon has the sequence 5'-AUG-3' as an anticodon.

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Prepare for your Biology 1050 final exam with this comprehensive review quiz. It covers key concepts such as protein structure, translation in eukaryotes, and post-translational modifications. Test your knowledge and ensure you're ready for the exam!

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