15 Questions
Match the following advantages of EIS with their corresponding descriptions:
Steady-state technique = Utilizes small signal analysis Wide range of applied frequency = Uses commercially available electrochemical working stations Less than 1 mHz to greater than 1 MHz = Utilizes small excitation signal Response of the biological signal is pseudo-linear = Current response to a sinusoidal potential will be a sinusoid at the same frequency but shifted in phase
Match the following components with their descriptions:
Biological recognition element = Useful in many applications involving electrochemical currents Metal-oxide-semiconductor field-effect transistor (MOSFET) = Commonly used for biological systems SARS-CoV-2 biosensor = A type of FET channel Ion-sensitive field-effect transistor (ISFET) = Used for sensing ions in solution
Match the following statements with their correct terms:
Pseudo-linear system = Current response to a sinusoidal potential is a sinusoid at the same frequency but shifted in phase Linear system = Current response is linear to the potential applied Small excitation signal = Used for measuring electrochemical impedance spectroscopy Sinusoidal potential = Induces a sinusoid current response
Match the following components with their respective descriptions in a Bio-FET biosensor:
Biological recognition element = Molecules binding induced surface potential changes MOSFET = Field-effect transistor gated by changes in surface potential SARS-CoV-2 biosensor = Biosensor used for detection of SARS-CoV-2 virus FET channel = Channel through which charge carriers flow in a field-effect transistor
Match the following terms with their corresponding roles in an ion-sensitive field-effect transistor (ISFET):
Biological recognition element = Detection of specific ions in solution MOSFET = Serving as the transistor component for ion sensing SARS-CoV-2 biosensor = Not typically associated with ISFET technology FET channel = Pathway for ion movement within the ISFET
Match the following concepts with their relevance to a Bio-FET biosensor:
Biological recognition element = Key for specific molecule detection MOSFET = Enables sensing through changes in surface potential SARS-CoV-2 biosensor = Specific application for detecting SARS-CoV-2 virus FET channel = Critical pathway for charge carrier flow in the sensor
Match the following terms with their connection to a metal-oxide-semiconductor field-effect transistor (MOSFET):
Biological recognition element = Not directly related to MOSFET operation MOSFET = Main component serving as a biosensor in Bio-FET technology SARS-CoV-2 biosensor = Utilizes MOSFET technology for virus detection FET channel = Integral part of the MOSFET structure
Match the following elements with their functions in a SARS-CoV-2 biosensor employing Bio-FET technology:
Biological recognition element = Identifies and binds to SARS-CoV-2 molecules MOSFET = Facilitates the detection process through surface potential alterations SARS-CoV-2 biosensor = Specifically designed for detecting the SARS-CoV-2 virus FET channel = Allows for the flow of charge carriers during sensing
Match the following components with their roles in an ion-sensitive field-effect transistor (ISFET) setup:
Biological recognition element = May be used to target specific ions for detection MOSFET = Part of the ISFET structure for ion sensing applications SARS-CoV-2 biosensor = Not typically associated with ISFET devices FET channel = Critical for ion movement detection within the ISFET
Match the following components with their roles in a Bio-FET:
Biological recognition element = Recognizes specific biomolecules Field-effect transistor = Underlying semiconductor material Ion-sensitive membrane = Replaces the metal gate in ISFET Reference electrode = Part of the ISFET structure
Match the following terms with their definitions:
MOSFET = Metal–oxide–semiconductor field-effect transistor ISFET = Ion-sensitive field-effect transistor FET channel = Part of the Bio-FET structure SARS-CoV-2 biosensor = Graphene transistor with spike protein antibody
Match the following statements with the correct technology:
Changes in charge distribution affect conductance = Bio-FET Metal gate replaced by ion-sensitive membrane = ISFET Surface functionalization with spike protein antibody = SARS-CoV-2 biosensor Variation in transistor channel related to detected protein amount = Graphene transistor
Match the following descriptions with their corresponding element:
Recognizes charged biomolecules = Biological recognition element Dielectric material that can be altered by charged molecules = FET gate Part of the ISFET structure = Electrolyte solution Part of the Bio-FET consisting of two main compartments = Field-effect transistor
Match the following components with their relevance to a SARS-CoV-2 biosensor:
Graphene transistor = Transistor channel variation proportional to detected protein amount Surface functionalization with spike protein antibody = Specific detection of SARS-CoV-2 proteins Ion-sensitive membrane = Replaces metal gate in ISFET structure Reference electrode = Integral part of graphene-based biosensors
Match the following features with their association to an ISFET:
Sensitive to ion concentration changes = ISFET Utilizes metal gate for charge distribution change = MOSFET Measures conductance variations in FET channel = Bio-FET Primarily used for specific protein detection = SARS-CoV-2 biosensor
Test your knowledge on BioFET and ISFET structures, which involve charged biomolecules binding to a FET gate and changing the conductance of the FET channel. Learn about the two main compartments of BioFETs and their similarities with ISFETs.
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