BioFET and ISFET Quiz

Steady-state technique = Utilizes small signal analysis Wide range of applied frequency = Uses commercially available electrochemical working stations Less than 1 mHz to greater than 1 MHz = Utilizes small excitation signal Response of the biological signal is pseudo-linear = Current response to a sinusoidal potential will be a sinusoid at the same frequency but shifted in phase

Biological recognition element = Useful in many applications involving electrochemical currents Metal-oxide-semiconductor field-effect transistor (MOSFET) = Commonly used for biological systems SARS-CoV-2 biosensor = A type of FET channel Ion-sensitive field-effect transistor (ISFET) = Used for sensing ions in solution

Pseudo-linear system = Current response to a sinusoidal potential is a sinusoid at the same frequency but shifted in phase Linear system = Current response is linear to the potential applied Small excitation signal = Used for measuring electrochemical impedance spectroscopy Sinusoidal potential = Induces a sinusoid current response

<p>Biological recognition element = Molecules binding induced surface potential changes MOSFET = Field-effect transistor gated by changes in surface potential SARS-CoV-2 biosensor = Biosensor used for detection of SARS-CoV-2 virus FET channel = Channel through which charge carriers flow in a field-effect transistor</p> Signup and view all the answers

<p>Biological recognition element = Detection of specific ions in solution MOSFET = Serving as the transistor component for ion sensing SARS-CoV-2 biosensor = Not typically associated with ISFET technology FET channel = Pathway for ion movement within the ISFET</p> Signup and view all the answers

<p>Biological recognition element = Key for specific molecule detection MOSFET = Enables sensing through changes in surface potential SARS-CoV-2 biosensor = Specific application for detecting SARS-CoV-2 virus FET channel = Critical pathway for charge carrier flow in the sensor</p> Signup and view all the answers

<p>Biological recognition element = Not directly related to MOSFET operation MOSFET = Main component serving as a biosensor in Bio-FET technology SARS-CoV-2 biosensor = Utilizes MOSFET technology for virus detection FET channel = Integral part of the MOSFET structure</p> Signup and view all the answers

<p>Biological recognition element = Identifies and binds to SARS-CoV-2 molecules MOSFET = Facilitates the detection process through surface potential alterations SARS-CoV-2 biosensor = Specifically designed for detecting the SARS-CoV-2 virus FET channel = Allows for the flow of charge carriers during sensing</p> Signup and view all the answers

<p>Biological recognition element = May be used to target specific ions for detection MOSFET = Part of the ISFET structure for ion sensing applications SARS-CoV-2 biosensor = Not typically associated with ISFET devices FET channel = Critical for ion movement detection within the ISFET</p> Signup and view all the answers

<p>Biological recognition element = Recognizes specific biomolecules Field-effect transistor = Underlying semiconductor material Ion-sensitive membrane = Replaces the metal gate in ISFET Reference electrode = Part of the ISFET structure</p> Signup and view all the answers

<p>MOSFET = Metal–oxide–semiconductor field-effect transistor ISFET = Ion-sensitive field-effect transistor FET channel = Part of the Bio-FET structure SARS-CoV-2 biosensor = Graphene transistor with spike protein antibody</p> Signup and view all the answers

<p>Changes in charge distribution affect conductance = Bio-FET Metal gate replaced by ion-sensitive membrane = ISFET Surface functionalization with spike protein antibody = SARS-CoV-2 biosensor Variation in transistor channel related to detected protein amount = Graphene transistor</p> Signup and view all the answers

<p>Recognizes charged biomolecules = Biological recognition element Dielectric material that can be altered by charged molecules = FET gate Part of the ISFET structure = Electrolyte solution Part of the Bio-FET consisting of two main compartments = Field-effect transistor</p> Signup and view all the answers

<p>Graphene transistor = Transistor channel variation proportional to detected protein amount Surface functionalization with spike protein antibody = Specific detection of SARS-CoV-2 proteins Ion-sensitive membrane = Replaces metal gate in ISFET structure Reference electrode = Integral part of graphene-based biosensors</p> Signup and view all the answers

<p>Sensitive to ion concentration changes = ISFET Utilizes metal gate for charge distribution change = MOSFET Measures conductance variations in FET channel = Bio-FET Primarily used for specific protein detection = SARS-CoV-2 biosensor</p> Signup and view all the answers