Biochemistry Lecture 9: Carbohydrate Disorders

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10 Questions

Which enzyme deficiency can lead to decreased intracellular ATP levels in red blood cells?

Pyruvate kinase deficiency

What is the first diseasemodifying agent approved for pyruvate kinase deficiency?

Mitapivat

What is the most common cause of metabolic acidosis identified in hospitalized individuals?

Elevated lactate levels

Under what conditions does lactate become an end product of glycolysis?

Anaerobic conditions

In which cells are the muscle cells and red blood cells the primary producers of lactic acid?

Muscle cells and red blood cells

What are the uncomfortable symptoms of lactose intolerance?

Gas, pain, diarrhea, and bloating

What is the main challenge for people who are lactose intolerant?

Finding alternative sources of calcium

What do defects in the glycolytic pathway cause?

Hemolytic anemia

Which natural sugar is difficult to digest for people with lactose intolerance?

Galactose

What are the energy sources created during the glycolytic pathway?

Adenosine triphosphate and nicotinamide adenine dinucleotide

Test your knowledge on carbohydrate disorders including lactose intolerance, acidosis, ketosis, and other related conditions. Prepared by Dr. Bnar.

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