Biochemistry Lecture 9: Carbohydrate Disorders
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Questions and Answers

Which enzyme deficiency can lead to decreased intracellular ATP levels in red blood cells?

  • Phosphofructokinase deficiency
  • Aldolase deficiency
  • Pyruvate kinase deficiency (correct)
  • Glucose-6-phosphate dehydrogenase deficiency

What is the first diseasemodifying agent approved for pyruvate kinase deficiency?

  • Splenectomy
  • Blood transfusions
  • Mitapivat (correct)
  • Exchange transfusion

What is the most common cause of metabolic acidosis identified in hospitalized individuals?

  • Respiratory diseases
  • Elevated lactate levels (correct)
  • Severe shock
  • Cancer

Under what conditions does lactate become an end product of glycolysis?

<p>Anaerobic conditions (C)</p> Signup and view all the answers

In which cells are the muscle cells and red blood cells the primary producers of lactic acid?

<p>Muscle cells and red blood cells (B)</p> Signup and view all the answers

What are the uncomfortable symptoms of lactose intolerance?

<p>Gas, pain, diarrhea, and bloating (A)</p> Signup and view all the answers

What is the main challenge for people who are lactose intolerant?

<p>Finding alternative sources of calcium (C)</p> Signup and view all the answers

What do defects in the glycolytic pathway cause?

<p>Hemolytic anemia (C)</p> Signup and view all the answers

Which natural sugar is difficult to digest for people with lactose intolerance?

<p>Galactose (D)</p> Signup and view all the answers

What are the energy sources created during the glycolytic pathway?

<p>Adenosine triphosphate and nicotinamide adenine dinucleotide (D)</p> Signup and view all the answers

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