Biochemistry Lecture 9: Carbohydrate Disorders
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Questions and Answers

Which enzyme deficiency can lead to decreased intracellular ATP levels in red blood cells?

  • Phosphofructokinase deficiency
  • Aldolase deficiency
  • Pyruvate kinase deficiency (correct)
  • Glucose-6-phosphate dehydrogenase deficiency
  • What is the first diseasemodifying agent approved for pyruvate kinase deficiency?

  • Splenectomy
  • Blood transfusions
  • Mitapivat (correct)
  • Exchange transfusion
  • What is the most common cause of metabolic acidosis identified in hospitalized individuals?

  • Respiratory diseases
  • Elevated lactate levels (correct)
  • Severe shock
  • Cancer
  • Under what conditions does lactate become an end product of glycolysis?

    <p>Anaerobic conditions</p> Signup and view all the answers

    In which cells are the muscle cells and red blood cells the primary producers of lactic acid?

    <p>Muscle cells and red blood cells</p> Signup and view all the answers

    What are the uncomfortable symptoms of lactose intolerance?

    <p>Gas, pain, diarrhea, and bloating</p> Signup and view all the answers

    What is the main challenge for people who are lactose intolerant?

    <p>Finding alternative sources of calcium</p> Signup and view all the answers

    What do defects in the glycolytic pathway cause?

    <p>Hemolytic anemia</p> Signup and view all the answers

    Which natural sugar is difficult to digest for people with lactose intolerance?

    <p>Galactose</p> Signup and view all the answers

    What are the energy sources created during the glycolytic pathway?

    <p>Adenosine triphosphate and nicotinamide adenine dinucleotide</p> Signup and view all the answers

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