30 Questions
What percentage of the final mark is attributed to Continuous Assessment?
40%
When is the Group Assignment due?
Friday February 23rd
What is the purpose of the Mid Semester Exam?
To evaluate student performance mid-semester
What is the consequence of missing a test?
Focus on the next test
How should students communicate with the lecturer?
Via email
What is one of the learning outcomes of this course?
Describe the reactions of the citric acid cycle
What is the primary function of the citric acid cycle?
To provide energy to the body
What percentage of ATP is synthesized in the Krebs cycle?
65-70%
What is the role of acetyl CoA in the citric acid cycle?
It is a metabolic intermediary
What is the primary source of oxygen consumption in the body?
Citric acid cycle
What is the name of the acid that participates at the outset of the citric acid cycle?
Citrate
What is the role of the citric acid cycle in connecting individual metabolic pathways?
It acts as an amphibole
What is the role of ADP in the citric acid cycle?
To ensure sufficient levels of NAD+ and FAD for the cycle to proceed
What happens when NADH and FADH2 accumulate?
The enzymes of the citric acid cycle are inhibited
What is the net ATP production by complete glucose oxidation?
38 ATP
Which of the following is an activator of the TCA cycle?
Ca2+
What is anaplerosis?
The replenishment of citric acid cycle intermediates
What happens to the citric acid cycle when energy charge of the cell is high?
It is inhibited by ATP, succinyl CoA, and NADH
Where are the enzymes of the TCA cycle located?
Mitochondrial matrix
What is the function of pyruvate translocases?
To transport pyruvate across the mitochondrial membrane
What is the function of the pyruvate dehydrogenase complex (PDH)?
To convert pyruvate to acetyl-CoA
What is the characteristic of acetyl-CoA?
High energy compound with a high energetic thioester bond
What is the first step in the reaction catalyzed by the PDH complex?
The acetyl group of pyruvate is attached to TPP
What is the byproduct of the conversion of pyruvate to acetyl-CoA?
CO2
In which tissues are high activities of pyruvate dehydrogenase (PDH) found?
Cardiac muscle and kidney
What is the byproduct of the first step of the PDH complex reaction?
CO2
What is the final product of the PDH complex reaction?
Acetyl-CoA
What is the role of dihydrolipoyl dehydrogenase in the PDH complex reaction?
Converts reduced lipoamide to oxidized lipoamide
What is the function of the PDH complex in glucose metabolism?
Converts pyruvate to Acetyl-CoA
How many ATP can be generated from 2 moles of pyruvate formed from glucose?
6 ATP
Assessment plan and lecture notes for Biochemistry II BMPS 111, covering the Citric Acid Cycle (Krebs Cycle/Tricarboxylic acid cycle). Includes information on assignment and exam mark calculations.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
