29 Questions
What percentage of the total marks is allocated to the midterm exam?
5%
What is the minimum number of questions expected in the written exam?
25-30
What is the central dogma according to the classic view?
DNA makes RNA and RNA makes protein
What is the primary purpose of proteins in the body?
To provide structure and function
How many lectures are planned in the Biochemistry I course?
5
What is NOT allowed during the lecture?
Recording
What is the characteristic of the peptide bond that helps to stabilize protein structure?
Partial double-bond character
What type of proteolysis is caused by low pH and/or high temperatures?
Non-specific proteolysis
What is the primary function of trypsin in proteolysis?
Cleaving peptide bonds after a positively charged residue
What is the level of protein structure that refers to local folded structures that form within a polypeptide?
Secondary structure
What type of bond links the alpha carbon atom to the amino group and the carbonyl carbon in a polypeptide?
Single bond
What is the type of interaction that stabilizes the primary structure of a protein?
Covalent bonds
What is the characteristic of the side chains of hydrophobic amino acids?
Nonpolar
What is unique about the amino group of Proline?
It is a secondary amino group
Which type of amino acids have side chains with hydroxyl (OH) groups?
Hydrophilic
What is the general characteristic of the R group of amino acids that determines their classification?
Polarity
What is the characteristic of aromatic hydrophobic amino acids?
They have aromatic side chains
What is the characteristic of acidic amino acids?
They contain a carboxylic acid group
What is the basis of chemical classification of amino acids?
The nature of the R group and its polarity
What is the result of the reaction between the carboxylic group of one amino acid and the amino group of another amino acid?
The formation of a peptide bond
What is the isoelectric point (pI) of an amino acid?
The pH at which the amino acid has a net zero charge
What type of bond is formed between amino acids?
Peptide bond
What determines the pI of an amino acid?
The nature of the side chain
What is the primary force responsible for the tertiary structure of a protein?
Interactions between the R groups of the amino acids
Which type of bond is formed between the SH groups of two cysteine residues?
Disulfide bond
What is the role of disulfide bonds in protein structure?
To maintain tertiary and quaternary structures
What type of interactions are involved in the tertiary structure of a protein?
Ionic interactions, disulfide bonds, hydrophobic interactions, and hydrogen bonding
What is the final three-dimensional form of a protein due to?
The more complicated folding and super-folding of the polypeptide chain in its secondary level
Which of the following bonds is less strong than the peptide bond and is liable to denaturation?
Disulfide bond
This quiz is based on the introductory lecture of Biochemistry I, covering fundamental concepts and principles. It is designed for Level II students in the Faculty of Pharmacy. Test your understanding of the subject with this quiz!
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