12 Questions
What is the primary reason for gene expression regulation in terms of energy conservation?
To reduce energy expenditure on unnecessary protein synthesis
What type of molecule is a transcription factor protein?
Trans-acting factor
What is the role of cAMP receptor protein (CRP) in the lac operon?
To communicate glucose levels to the promoter
What is the purpose of chromatin remodeling in gene expression regulation?
To change the structure of chromatin to access or deny access to transcription factors
What is the significance of cis-acting sequences in gene expression regulation?
They are DNA sequences that flanking a gene and influence its expression
What is the net result of positive control in gene expression regulation?
Stimulation of transcription by binding to the promoter
What is the primary target of alpha-amanitin?
DNA pol II
What is the mechanism of action of diphtheria toxin?
ADP-ribosylation of eEF2
What is the primary target of ciprofloxacin?
DNA gyrase
How does chloramphenicol inhibit protein synthesis?
By binding to the 50S subunit of the bacterial ribosome
What is the primary mechanism of action of ampicillin?
Inhibition of bacterial cell wall synthesis
What is the primary target of methotrexate?
Dihydrofolate reductase (DHFR)
Test your knowledge on the mechanism of action of various chemical compounds including alpha-amanitin, diphtheria toxin, ciprofloxacin, and more. Learn how they affect DNA pol I, II, and III, and their effects on gene transcription.
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