Biochemistry: Coupled Reactions
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Questions and Answers

What are coupled reactions?

Where a spontaneous exergonic reaction is used to drive a non-spontaneous endergonic reaction by coupling together.

Give an example of a coupled reaction.

The coupling of the exergonic hydrolysis of ATP with the endergonic reaction of glucose to lactic acid.

Change in G is the maximum ______ that can be obtained from a chemical reaction.

work

Change in G is the driving force for ______.

<p>physical and chemical change</p> Signup and view all the answers

If Change in G is zero, the system is at equilibrium.

<p>True</p> Signup and view all the answers

What are the equations for Change in G?

<p>Change in G = Change in G + RT ln Q and Change in G = -RT ln K</p> Signup and view all the answers

Study Notes

Coupled Reactions

  • Coupled reactions combine a spontaneous exergonic reaction with a non-spontaneous endergonic reaction, enabling the latter to proceed through energy transfer.

Example of a Coupled Reaction

  • The hydrolysis of ATP, an exergonic process, can be coupled with the endergonic reaction of glucose converting into lactic acid, maintaining a negative change in Gibbs free energy (ΔG).

ΔG and Work

  • ΔG represents the maximum amount of work obtainable from a chemical reaction, providing insights into the efficiency and spontaneity of the reaction.

ΔG as Driving Force

  • Change in Gibbs free energy (ΔG) serves as the driving force behind both physical and chemical transformations, indicating whether a process can occur spontaneously.

Equilibrium Condition

  • When ΔG equals zero, the system is in a state of equilibrium, meaning there is no net change occurring in the concentration of reactants and products.

Equations for ΔG

  • Two key formulas for calculating ΔG include:
    • ΔG = ΔG° + RT ln Q
    • ΔG = -RT ln K
  • These equations relate standard Gibbs free energy change to reaction quotients (Q) and equilibrium constants (K).

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Description

This quiz covers the concept of coupled reactions in biochemistry, where a spontaneous exergonic reaction drives a non-spontaneous endergonic reaction. Explore examples, like the hydrolysis of ATP coupled with glucose metabolism. Test your understanding of these crucial biochemical processes.

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