Biochemical Profiles Overview
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Questions and Answers

Which of the following is NOT a component of the liver function tests profile?

  • Alkaline phosphatase
  • AST
  • Thyroid function (correct)
  • Total bilirubin
  • Which of the following is not a function of the liver?

  • Synthesis of clotting factors
  • Production of bile
  • Storage of glycogen
  • Excretion of TSH (correct)
  • What is the duration threshold for subacute liver disease?

  • 12 weeks - 1 year
  • More than 6 months
  • Less than 8 weeks
  • 8 weeks - 6 months (correct)
  • Which of the following is NOT a part of the lipids profile or coronary risk profile?

    <p>Creatinine clearance</p> Signup and view all the answers

    Which of the following is a function of the liver related to metabolism?

    <p>Metabolism of carbohydrates, lipids and proteins</p> Signup and view all the answers

    What percentage of liver tissue can sustain life even when functioning?

    <p>10-20%</p> Signup and view all the answers

    Which liver function test measures the ability of the liver to clear endogenous or exogenous substances from the circulation?

    <p>Gammaglutamyl transferase (GGT)</p> Signup and view all the answers

    In which condition does excessive accumulation of extracellular matrix proteins, including collagen, occur in chronic liver diseases?

    <p>Liver fibrosis</p> Signup and view all the answers

    Which liver disease results in scar tissue replacing healthy liver tissue, blocking blood flow and preventing proper functioning?

    <p>Cirrhosis</p> Signup and view all the answers

    Which of the following is a limitation of liver function tests?

    <p>Lack of sensitivity in detecting liver fibrosis</p> Signup and view all the answers

    What is the normal A/G ratio for total protein in serum?

    <p>1.2 – 2.5</p> Signup and view all the answers

    Which liver function test measures the biosynthetic capacity of the liver?

    <p>Prothrombine time and activity</p> Signup and view all the answers

    What is the main consequence of advanced liver fibrosis?

    <p>Cirrhosis</p> Signup and view all the answers

    Which liver function test evaluates response to treatment or adjusts treatment?

    <p>Total serum bilirubin</p> Signup and view all the answers

    "To detect injury in hepatocytes" relates to which general category of liver function tests?

    <p>&quot;Tests to detect injury in hepatocytes&quot;</p> Signup and view all the answers

    What is one common factor that may cause elevation of AST and ALT levels?

    <p>Acetaminophen</p> Signup and view all the answers

    The lipids profile or coronary risk profile includes measurements of HDL, LDL, and VLDL?

    <p>True</p> Signup and view all the answers

    The liver plays a role in heme metabolism?

    <p>True</p> Signup and view all the answers

    Liver function tests can accurately assess the degree of liver fibrosis?

    <p>False</p> Signup and view all the answers

    The A/G ratio is used to evaluate protein metabolism in the liver?

    <p>False</p> Signup and view all the answers

    Liver function tests are limited in their ability to diagnose specific liver diseases?

    <p>True</p> Signup and view all the answers

    Liver tissue can sustain life even when only 5-10% of the liver tissue is functioning?

    <p>False</p> Signup and view all the answers

    Chronic liver disease is defined as abnormal liver chemistries for less than 6 months.

    <p>False</p> Signup and view all the answers

    Liver fibrosis does not result in cirrhosis, liver failure, and portal hypertension.

    <p>False</p> Signup and view all the answers

    Total proteins may decrease in dehydration (vomiting or diarrhea).

    <p>False</p> Signup and view all the answers

    Tests for the capacity of the liver to transport organic anions and metabolize drugs include serum bilirubin.

    <p>True</p> Signup and view all the answers

    Elevated aminotransferase levels may be elevated in musculoskeletal or cardiac disease.

    <p>True</p> Signup and view all the answers

    Liver function tests can provide a specific diagnosis of liver disease.

    <p>False</p> Signup and view all the answers

    Cirrhosis does not involve scar tissue replacing healthy liver tissue.

    <p>False</p> Signup and view all the answers

    The biosynthetic capacity of the liver is measured by serum albumin and prothrombin time.

    <p>True</p> Signup and view all the answers

    Hepatitis A is an example of an immune disease affecting the liver.

    <p>False</p> Signup and view all the answers

    Serum albumin test is used to detect liver fibrosis.

    <p>False</p> Signup and view all the answers

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