Bioavailability and Bioequivalence Quiz

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What is the expression for the fraction of the dose which is absorbed from the gut?

fg (correct)

First pass clearance

F

fH

What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?

fg

fH

First pass clearance (correct)

F

What does the bioavailability depend on?

F

First pass clearance

fg

fH (correct)

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

To determine the effect of excipients, the patient related factors on efficiency of absorption of drugs Signup and view all the answers

What is the expression for bioavailability?

F Signup and view all the answers

What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?

F Signup and view all the answers

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

Development of a suitable dosage form for a new drug Signup and view all the answers

What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?

fg Signup and view all the answers

What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?

F Signup and view all the answers

What does the bioavailability depend on?

fH and F Signup and view all the answers

Bioavailability and Bioequivalence Quiz

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Questions and Answers

What is the expression for the fraction of the dose which is absorbed from the gut?

What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?

What does the bioavailability depend on?

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

What is the expression for bioavailability?

What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?

What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?

What does the bioavailability depend on?

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