Bioavailability and Bioequivalence Quiz

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Questions and Answers

What is the expression for the fraction of the dose which is absorbed from the gut?

  • fg (correct)
  • First pass clearance
  • F
  • fH

What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?

  • fg
  • fH
  • First pass clearance (correct)
  • F

What does the bioavailability depend on?

  • F
  • First pass clearance
  • fg
  • fH (correct)

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

<p>To determine the effect of excipients, the patient related factors on efficiency of absorption of drugs (D)</p> Signup and view all the answers

What is the expression for bioavailability?

<p>F (C)</p> Signup and view all the answers

What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?

<p>F (A)</p> Signup and view all the answers

What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

<p>Development of a suitable dosage form for a new drug (B)</p> Signup and view all the answers

What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?

<p>fg (D)</p> Signup and view all the answers

What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?

<p>F (D)</p> Signup and view all the answers

What does the bioavailability depend on?

<p>fH and F (B)</p> Signup and view all the answers

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