Bioavailability and Bioequivalence Quiz
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Questions and Answers

What is the expression for the fraction of the dose which is absorbed from the gut?

  • fg (correct)
  • First pass clearance
  • F
  • fH

    • What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?

  • fg
  • fH
  • First pass clearance (correct)
  • F

    • What does the bioavailability depend on?

  • F
  • First pass clearance
  • fg
  • fH (correct)

    • What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

    <p>To determine the effect of excipients, the patient related factors on efficiency of absorption of drugs</p> Signup and view all the answers

    What is the expression for bioavailability?

    <p>F</p> Signup and view all the answers

    What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?

    <p>F</p> Signup and view all the answers

    What is the aim of bioavailability studies related to the development of new formulation of already known drugs?

    <p>Development of a suitable dosage form for a new drug</p> Signup and view all the answers

    What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?

    <p>fg</p> Signup and view all the answers

    What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?

    <p>F</p> Signup and view all the answers

    What does the bioavailability depend on?

    <p>fH and F</p> Signup and view all the answers

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