Podcast
Questions and Answers
What is the expression for the fraction of the dose which is absorbed from the gut?
What is the expression for the fraction of the dose which is absorbed from the gut?
- fg (correct)
- First pass clearance
- F
- fH
What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?
What is the extent to which the drug is removed by the liver during its first passage in the portal blood through the liver to the systemic circulation?
- fg
- fH
- First pass clearance (correct)
- F
What does the bioavailability depend on?
What does the bioavailability depend on?
- F
- First pass clearance
- fg
- fH (correct)
What is the aim of bioavailability studies related to the development of new formulation of already known drugs?
What is the aim of bioavailability studies related to the development of new formulation of already known drugs?
What is the expression for bioavailability?
What is the expression for bioavailability?
What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?
What is the expression for the fraction of the dose which reaches the systemic circulation as unchanged drug?
What is the aim of bioavailability studies related to the development of new formulation of already known drugs?
What is the aim of bioavailability studies related to the development of new formulation of already known drugs?
What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?
What represents the extent to which the unchanged drug is absorbed from the gut lumen into the portal circulation?
What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?
What is the expression for the fraction of drug which escapes the first pass clearance from the portal blood?
What does the bioavailability depend on?
What does the bioavailability depend on?