Bioactive Materials
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Questions and Answers

bioactivity is?

  • The ability to stimulate reparative dentine formation
  • The property of a material to induce bactericidal effects
  • The ability to promote tooth remineralization
  • The ability of a material to elicit a response in a living tissue (correct)

    • What is a property of an ideal bioactive material?

  • Being inert
  • Stimulating reparative dentine formation (correct)
  • Sterility
  • Bactericidal effects

    • Which of the following is NOT a use of BioActive Materials?

  • Preventing tooth decay (correct)
  • Promoting tooth remineralization
  • Pulp capping material
  • Dentinal tubule occlusion

    • Which of the following BioActive Materials is a type of ceramic?

    <p>Sol-gel-derived bioactive glass (BAG) ceramic containing silver ions (Ag-BG)</p> Signup and view all the answers

    Who developed Mineral Trioxide Aggregate (MTA) for use as a dental root repair material?

    <p>The author of the research paper</p> Signup and view all the answers

    What is NOT an ideal property of a bioactive material?

    <p>Inert</p> Signup and view all the answers

    After an 8-month reassessment, what suggests healing of the periapical lesion?

    <p>Continuous lamina dura and consistent width of periodontal ligament space</p> Signup and view all the answers

    What is the primary goal of apexogenesis during pulpal treatment?

    <p>To maintain pulp vitality and allow continued root development</p> Signup and view all the answers

    What is the purpose of bleedin control in MTA pulpotomy?

    <p>To control hemorrhage and allow MTA setting</p> Signup and view all the answers

    What is the primary advantage of using MTA over formocresol in pulpotomy?

    <p>MTA promotes pulp regeneration and vitality</p> Signup and view all the answers

    What is the typical duration required for apical closure to occur after eruption?

    <p>3 years after eruption</p> Signup and view all the answers

    What is the purpose of the moist cotton pellet in MTA pulpotomy?

    <p>To allow MTA to set on the pulp tissue</p> Signup and view all the answers

    What percentage of MTA is comprised of Portland cement?

    <p>75%</p> Signup and view all the answers

    What is the primary purpose of adding bismuth oxide to MTA?

    <p>To improve its radiopacity</p> Signup and view all the answers

    What is the pH of MTA after 3 hours?

    <p>12.5</p> Signup and view all the answers

    Why is a moistened cotton pellet placed in contact with MTA?

    <p>To enhance its sealing ability</p> Signup and view all the answers

    What is the compressive strength of MTA after 28 days?

    <p>133 MPa</p> Signup and view all the answers

    What is the main reason why MTA is a biocompatible material?

    <p>Due to its ability to generate calcium and phosphate ions</p> Signup and view all the answers

    Which of the following is NOT a characteristic of Biodentine?

    <p>It is not suitable for use as a dentine replacement material</p> Signup and view all the answers

    What is the title of the scientific file published by Septodont, Paris, France?

    <p>Biodentine Active Biosilicate Technology Scientific File</p> Signup and view all the answers

    According to a study by L. Grech, B. Mallia, and J. Camilleri, what is a characteristic of Biodentine?

    <p>It has been investigated for use as a dentine replacement material</p> Signup and view all the answers

    What is the title of the journal in which a study on the shear bond strengths of different adhesive systems to Biodentine was published?

    <p>The Scientific World Journal</p> Signup and view all the answers

    Which of the following investigators has studied the physical properties of tricalcium silicate cement-based root-end filling materials?

    <p>L. Grech</p> Signup and view all the answers

    What is the volume and page numbers of the International Endodontic Journal in which a study on the characterization of set intermediate restorative material was published?

    <p>Vol. 46, pp. 632-641</p> Signup and view all the answers

    What is a significant advantage of MTA over Formocresol in clinical applications?

    <p>Less time required for the procedure</p> Signup and view all the answers

    Why is Formocresol not preferred in clinical applications?

    <p>It is tissue irritant, cytotoxic, and mutagenic</p> Signup and view all the answers

    What is a limitation of MTA in clinical applications?

    <p>It is not used in area open to oral environment</p> Signup and view all the answers

    What is a drawback of MTA?

    <p>It has a discoloration potential</p> Signup and view all the answers

    What is a reason why MTA is not used as a permanent filling material?

    <p>It has a low compressive strength</p> Signup and view all the answers

    What is a challenge of removing MTA after curing?

    <p>It is difficult to remove because of the absence of a known solvent</p> Signup and view all the answers

    What is a primary indication for using Biodentine?

    <p>As a base under amalgam or composite in deep carious teeth</p> Signup and view all the answers

    What is a benefit of using Biodentine as a pulp capping material?

    <p>It promotes pulp vitality and healing</p> Signup and view all the answers

    What is a characteristic of Biodentine that makes it suitable for dentine replacement?

    <p>Its dentin-like mechanical properties</p> Signup and view all the answers

    What is a benefit of using Biodentine compared to other materials?

    <p>It has better handling and manipulation characteristics</p> Signup and view all the answers

    What is a composition of Biodentine powder?

    <p>Tricalcium silicate, calcium carbonate, and iron oxide</p> Signup and view all the answers

    How is Biodentine typically mixed and prepared for use?

    <p>By triturating the powder and liquid in a capsule for 30 seconds</p> Signup and view all the answers

    What is the primary indication for using biodentine in vital pulpotomy?

    <p>When the coronal pulp tissue is inflamed and a direct pulp capping is not a suitable option</p> Signup and view all the answers

    What is the advantage of using biodentine for perforation repair?

    <p>It has good adhesion to dentin surface and fast setting time</p> Signup and view all the answers

    What is a unique property of biodentine that makes it suitable for apexification in necrotic immature teeth?

    <p>It induces formation of new cementum and periodontal ligament</p> Signup and view all the answers

    What is the advantage of using biodentine over formocresol in pulpotomy?

    <p>It has a higher success rate</p> Signup and view all the answers

    What is the reason why biodentine is preferred for dentin bridge formation?

    <p>It induces odontoblast stimulation</p> Signup and view all the answers

    What is the potential of biodentine in endodontics and operative dentistry?

    <p>It has great potential to revolutionize the different aspects of managing primary and permanent teeth</p> Signup and view all the answers

    What is the primary goal of using biodentine as a dentine replacement material?

    <p>To promote pulp regeneration</p> Signup and view all the answers

    Which of the following mechanical properties of biodentine was investigated by L. Grech, B. Mallia, and J. Camilleri?

    <p>Compressive strength</p> Signup and view all the answers

    What is the potential clinical application of biodentine as a root-end filling material?

    <p>Endodontic treatment</p> Signup and view all the answers

    What is the effect of acid etching procedures on the compressive strength of biodentine?

    <p>It decreases the compressive strength</p> Signup and view all the answers

    What is the significance of the study by M.B. Kayahan et al. on the compressive strength of biodentine?

    <p>It showed the effect of acid etching on the compressive strength of biodentine</p> Signup and view all the answers

    What is the potential advantage of using biodentine as a dentine replacement material over other materials?

    <p>It has better biocompatibility</p> Signup and view all the answers

    What is the significance of the study by J. Camilleri on biodentine as a dentine replacement material?

    <p>It investigated the physical properties of biodentine as a dentine replacement material</p> Signup and view all the answers

    What is the potential limitation of using biodentine as a root-end filling material?

    <p>It is not suitable for use in certain clinical situations</p> Signup and view all the answers

    Study Notes

    Bioactive Materials

    • Bioactive materials are materials that elicit a response in living tissue and induce the formation of a bond between tissue and the material.
    • The ideal properties of bioactive materials include:
      • Bactericidal and bacteriostatic properties
      • Sterility
      • Stimulation of reparative dentine formation
      • Maintenance of pulp vitality
    • Uses of bioactive materials include:
      • Pulp capping material
      • Permanent restorations
      • Dentinal tubule occlusion
      • Prevention of dentinal hypersensitivity
      • Regeneration of bone tissue and promotion of tooth remineralization

    Bioactive Materials Examples

    • Calcium hydroxide
    • Mineral trioxide aggregate (MTA)
    • Calcium-enriched mixture (CEM)
    • Biodentine
    • Inert materials (isobutyl cyanoacrylate and tricalcium phosphate ceramic)
    • ActiveTM BioACTIVE restorative material
    • Pulpdent (composite resin that releases more fluoride than glass ionomers)
    • MTYA1-Ca filler
    • Tetracalcium phosphate (TTCP)
    • Sol-gel-derived bioactive glass (BAG) ceramic containing silver ions (Ag-BG)
    • Calcium phosphate
    • Novel endodontic cement (NEC)
    • Endo sequence root repair material

    MTA (Mineral Trioxide Aggregate)

    • Developed by Dr. Mahmoud Torabinejad for use as a dental root repair material
    • Composed primarily of:
      • 75% Portland cement
      • 20% bismuth oxide (Bi2O3)
      • 5% calcium sulfate dihydrate or gypsum (CaSO4 ∙ 2H2O)
    • Additional minor trace elements may be present
    • Properties:
      • Biocompatible
      • Non-resorbable
      • Radioopaque
      • Antimicrobial
      • Compressive strength develops over 28 days
      • Low solubility
      • pH: initially 10.2, after 3 hours: 12.5 (remains constant)
    • Uses:
      • Sealing communications between the root canal system and the periodontium
      • Pulpotomy and apexification
      • Apexogenesis (vital pulp therapy)

    MTA Properties

    • Setting time: 2 hours and 45 minutes
    • Expands during setting reaction, increasing sealing ability
    • Moistened cotton pellet should be placed in contact with MTA before placement of the permanent restoration

    Comparison with Formocresol

    • MTA has low toxic effects, increased tissue regeneration properties, and good clinical results
    • Formocresol has been criticized for its tissue irritant, cytotoxic, and mutagenic effects
    • MTA is applied directly without cotton pellet, reducing the risk of bleeding and reoccurrence of bleeding

    MTA Limitations

    • Not used in areas open to the oral environment due to solubility in acidic environments
    • Not recommended for obturation of primary teeth due to slow resorption
    • Not used with anterior teeth due to discoloration potential
    • Not used as a permanent filling due to low compressive strength

    MTA Drawbacks

    • Discoloration potential
    • Presence of toxic elements in the material composition
    • Difficult handling characteristics
    • Long setting time
    • High material cost
    • Absence of a known solvent for the material
    • Difficulty of removal after curing
    • Low compressive strength incompatible with restorative indications

    Biodentine Overview

    • Biodentine is an all-in-one, biocompatible, and bioactive material for dentine replacement, commercially available since 2009.
    • Composition: tricalcium silicate, dicalcium silicate, calcium carbonate, iron oxide, and zirconium oxide.

    Composition and Manipulation

    • Powder: tricalcium silicate, dicalcium silicate, calcium carbonate, and iron oxide.
    • Liquid: calcium chloride and hydrosoluble polymer.
    • Mixing ratio: 1 capsule powder to 5 drops of liquid.
    • Setting time: approximately 12 minutes.

    Advantages

    • Helps in remineralization of dentine.
    • Preserves pulp vitality and promotes pulp healing.
    • Replaces natural dentine with similar mechanical properties.
    • Better handling and manipulation.
    • Reduced setting time.

    Dental Applications

    Dentine Replacement

    • Biodentine can be used as a permanent dentine substitute (base) under composite or amalgam, especially in deep carious teeth.

    Pulp Capping

    • Can be used as a pulp capping material, encouraging pulp healing and dentin bridge formation.

    Pulpotomy

    • Used as a vital pulp therapy method, with a higher success rate than MTA.

    Repair of Perforations

    • Preferred for perforation repair in root canal or pulp chamber floor due to good adhesion to dentin surface and fast setting time.

    Repair of Resorption

    • Biocompatibility and ability to induce calcium-phosphate precipitation make it suitable for bone tissue repair.

    Apexification

    • Can be used in necrotic immature teeth, inducing formation of new cementum and periodontal ligament.

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    Related Documents

    CTD week 9.pptx

    Description

    Learn about bioactive materials, their ability to elicit a response in living tissue, and their applications in endodontics. Explore the formation of bonds between tissue and material.

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