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Questions and Answers
According to the provided information, what is the primary challenge faced by air-breathers regarding CO2 excretion?
According to the provided information, what is the primary challenge faced by air-breathers regarding CO2 excretion?
- The limited surface area available for gas exchange in the respiratory system, affecting CO2 removal.
- The rapid conversion of CO2 to carbonic acid in the lungs, hindering direct excretion.
- The high concentration of CO2 in the air, creating a diffusion gradient that is unfavorable for excretion.
- The low concentration of CO2 in the air necessitates a high partial pressure of CO2 for diffusion to occur. (correct)
In mammals, which of the following chemoreceptors plays the most significant role in regulating breathing, as indicated by the content?
In mammals, which of the following chemoreceptors plays the most significant role in regulating breathing, as indicated by the content?
- Central chemoreceptors in the medulla. (correct)
- Peripheral chemoreceptors in the carotid bodies.
- Peripheral chemoreceptors in the aortic bodies.
- Both peripheral and central chemoreceptors play equal roles in regulating overall breathing.
Considering the information provided, what is the main advantage water-breathers have over air-breathers in regard to CO2 excretion?
Considering the information provided, what is the main advantage water-breathers have over air-breathers in regard to CO2 excretion?
- Water-breathers usually have low CO2 concentrations in water, which allows for easier diffusion out of their body. (correct)
- Water-breathers have high concentrations of CO2 in their respiratory medium, causing a higher expulsion gradient.
- The higher solubility of CO2 in water facilitates better excretion of the gas for water-breathers.
- Water-breathers have a more developed respiratory system, allowing for efficient transfer.
For bimodal breathers, how is blood typically re-routed to manage oxygen and carbon dioxide exchange effectively?
For bimodal breathers, how is blood typically re-routed to manage oxygen and carbon dioxide exchange effectively?
Based on the provided content, what strategy do some air-breathing animals use when in water?
Based on the provided content, what strategy do some air-breathing animals use when in water?
In the context of oxygen transport, what is the role of respiratory pigments, and what unique adaptation is observed in the Antarctic icefish?
In the context of oxygen transport, what is the role of respiratory pigments, and what unique adaptation is observed in the Antarctic icefish?
According to the content, what is the primary mechanism by which most carbon dioxide is transported in the blood, and what role does carbonic anhydrase (CA) play in this process?
According to the content, what is the primary mechanism by which most carbon dioxide is transported in the blood, and what role does carbonic anhydrase (CA) play in this process?
Based on the content, in what direction will the reaction $HbH + O_2 \rightleftharpoons HbO_2 + H^+$ in the tissues and the lungs?
Based on the content, in what direction will the reaction $HbH + O_2 \rightleftharpoons HbO_2 + H^+$ in the tissues and the lungs?
During CO2 excretion at working tissues, how is the charge balance maintained when bicarbonate ($HCO_3^−$) is transported from red blood cells to the plasma, and what specific protein is responsible for this process?
During CO2 excretion at working tissues, how is the charge balance maintained when bicarbonate ($HCO_3^−$) is transported from red blood cells to the plasma, and what specific protein is responsible for this process?
Following the description of $CO_2$ excretion, what happens to the majority of $HCO_3^−$ when it reaches the gas exchange surface (lungs/gills)?
Following the description of $CO_2$ excretion, what happens to the majority of $HCO_3^−$ when it reaches the gas exchange surface (lungs/gills)?
Flashcards
CO2 Excretion
CO2 Excretion
The process of removing carbon dioxide (CO2) from the body.
CO2 Excretion in Air Breathers
CO2 Excretion in Air Breathers
The partial pressure of CO2 (pCO2) in the air is relatively low. This makes diffusion of CO2 from the body to the air challenging for air-breathing animals.
Fick's Law of Diffusion
Fick's Law of Diffusion
The rate of diffusion is directly proportional to the surface area and the difference in partial pressure (P1 - P2) between the two compartments, and inversely proportional to the distance (X).
Peripheral Chemoreceptors
Peripheral Chemoreceptors
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Nitrogenous Waste in Freshwater Fish
Nitrogenous Waste in Freshwater Fish
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Respiratory Pigments and Oxygen Carrying Capacity
Respiratory Pigments and Oxygen Carrying Capacity
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Bohr Effect
Bohr Effect
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CO2 Transport and Bicarbonate Formation
CO2 Transport and Bicarbonate Formation
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CO2 Excretion: From Tissue to Respiratory Surface
CO2 Excretion: From Tissue to Respiratory Surface
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Band 3 Protein and Bicarbonate Transport
Band 3 Protein and Bicarbonate Transport
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Study Notes
Lecture 6: Gas Exchange
- Lecture date: January 17
- Topics covered: CO2 exchange, regulating breathing
- Reading assignments: pages 677-685 and 620-638
- Review pages: 654-677
Respiratory Pigments
- Covered in Bio 2601
- Students expected to know the topic
- Students should understand hematocrit
- Blood components diagram included
Antarctic Icefish
- Lives in -1.9°C water
- Lacks respiratory pigments
- How does it get enough oxygen?
- Possible advantages of lacking respiratory pigments?
- Are there other animals without respiratory pigments?
Pigments & Oxygen Carrying Capacity
- Graph showing oxygen equilibrium curve (total O2)
- Relationship between partial pressure of O2 and oxygen content of blood
- P50 values are shown on second graph
- Describes high/low hemoglobin content
Percent Saturation of Oxygen
- Graph shows percent saturation vs. partial pressure of O2
- Formula shown is HpH + O2 ↔ HbO2 + H+
Oxygen Concentration of Blood
- Graph showing O2 concentration vs. partial pressure of oxygen in blood
- Illustrates changes in O2 concentration during rest and exercise
Effect of Temperature on P50
- Graph showing how temperature affects oxygen saturation curves
- Partial pressure of O2 in the blood is shown on graph
Hemoglobin at Working Tissues
- Graph shows effect of pH change on hemoglobin saturation
- Different pH levels (7.6, 7.4 and 7.2) are shown on the graph
- Variation of CO₂ partial pressure are included on the graph
CO2 Excretion
- Location of CO2 production
- CO2 diffuses freely across epithelia/membranes
- CO2 is not very soluble
- Converting CO2 to bicarbonate (HCO3-)
- Most CO2 transported as bicarbonate
- Carbonic anhydrase role in RBCs
- Diagram showing conversion reaction
CO2 Excretion: Working Tissues
- CO2 diffuses from tissue to plasma & RBCs
- Little CO2 binds to hemoglobin (Hb)
- Converts to carbonic acid (H₂CO₃) by carbonic anhydrase (CA)
- Then to bicarbonate (HCO₃⁻)
- What happens to H⁺? effect on Hb?
- Bicarbonate moves to plasma
- Rapid anion exchange protein carries chloride ions (Cl⁻) into cells instead of bicarbonate
- Explains CO2 transport in plasma as bicarbonate
CO2 Excretion: Gas Exchange Surface
- Bicarbonate (HCO₃⁻) cannot diffuse across membranes
- Converting back to CO2 for release
- Effect on equilibrium
CO2 Excretion in Air-Breathers
- Challenge of low CO2 levels in air
- High pCO2 is needed for diffusion
- Graph relating CO2 partial pressure to oxygen partial pressure
Blood Gases & Breathing
- Chemoreceptors (peripheral, carotid, and aortic bodies and central medulla) involved in detecting blood gas levels
- Details on chemoreceptor locations and roles
Regulating Breathing and Data Interpretations
- Graphs relating ventilation rate (% values) to O2/CO2 % values in air/water breathers.
- Data interpretations for air breathers
Unusual Air-Breathers
- Issue of CO2 concentration for air breathers
- Coping strategies used by different species
CO2 Excretion in Water-Breathers
- CO2 excretion is generally easy in water due to water's solubility of CO2
- conversion to bicarbonate
- Diffusion gradient for CO2 and its consequences
What about Water Breathers?
- Diagram showing oxygen partial pressure in relation to ventilation rate
- Data for varieties of water vent rates
Gas Exchange: Bimodal Breathers
- Oxygen exchange mainly via lungs
- Carbon dioxide exchange mainly via gills
- Blood routing required
Gas Exchange: Skin Breathers
- Oxygen exchange through lungs and permeable skin
- CO2 excretion data interpretation
Unusual Water Breathers
- Nitrogenous waste excretion by freshwater fish
- Conversion to ammoniac
- Soda lakes/water high in CO2
Ornithine-Urea Cycle
- Diagram of the cycle, and metabolic pathways involved
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