Biliary Tract Diseases and Primary Sclerosing Cholangitis

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Which pattern of liver function tests (LFTs) is typically seen in biliary tract disease?

Elevated unconjugated bilirubin

Elevated cholesterol

Elevated gamma-glutamyl transferase (GGT)

Elevated alkaline phosphatase (ALP) (correct)

What is the classic presentation of primary sclerosing cholangitis?

Antimitochondrial antibody positivity

Middle-aged males with ulcerative colitis

Pruritus and jaundice

Alternating strictures and dilation of bile ducts (correct)

Which autoantibody is typically positive in primary biliary cholangitis?

Anti-smooth muscle antibody

Antinuclear antibody

Anti-liver kidney microsomal antibody

Antimitochondrial antibody (correct)

Which condition is associated with primary biliary cholangitis?

All of the above Signup and view all the answers

What is the treatment for primary biliary cholangitis?

Ursodiol Signup and view all the answers

What is the most common cause of secondary biliary cirrhosis?

Gallstones Signup and view all the answers

What is the pathophysiology of secondary biliary cirrhosis?

Elevated bile pressure and injury/fibrosis Signup and view all the answers

Which gender is most commonly affected by primary biliary cholangitis?

Females Signup and view all the answers

What is the most common complication of primary sclerosing cholangitis?

Biliary cirrhosis Signup and view all the answers

Which autoantibody is typically positive in primary sclerosing cholangitis?

Perinuclear antineutrophil cytoplasmic antibody (p-ANCA) Signup and view all the answers

Which condition is characterized by concentric 'onion skin' bile duct fibrosis and alternating strictures and dilation of intra- and extrahepatic bile ducts?

Primary sclerosing cholangitis Signup and view all the answers

Which condition is associated with ulcerative colitis?

Primary sclerosing cholangitis Signup and view all the answers

Which condition is characterized by autoimmune reaction leading to destruction of lobular bile ducts?

Primary biliary cholangitis Signup and view all the answers

Which condition is typically seen in middle-aged females?

Primary biliary cholangitis Signup and view all the answers

Which condition is characterized by extrahepatic biliary obstruction and increased pressure in intrahepatic ducts?

Secondary biliary cirrhosis Signup and view all the answers

Which condition is associated with known obstructive lesions such as gallstones and biliary strictures?

Secondary biliary cirrhosis Signup and view all the answers

Which condition may present with pruritus, jaundice, dark urine, light-colored stool, and hepatosplenomegaly?

Biliary tract disease Signup and view all the answers

Which condition is characterized by a cholestatic pattern of liver function tests (LFTs) with increased conjugated bilirubin, cholesterol, ALP, and GGT?

Biliary tract disease Signup and view all the answers

Which condition is associated with other autoimmune conditions such as Hashimoto thyroiditis and rheumatoid arthritis?

Primary biliary cholangitis Signup and view all the answers

Which condition can lead to secondary biliary cirrhosis and an increased risk of cholangiocarcinoma and gallbladder cancer?

Primary sclerosing cholangitis Signup and view all the answers

Which of the following symptoms is commonly seen in biliary tract disease?

Abdominal pain Signup and view all the answers

Which liver function test (LFT) pattern is typically observed in biliary tract disease?

Increased conjugated bilirubin and ALP Signup and view all the answers

Which of the following conditions is characterized by concentric 'onion skin' bile duct fibrosis and alternating strictures and dilation of intra- and extrahepatic bile ducts?

Primary sclerosing cholangitis Signup and view all the answers

Biliary Tract Diseases and Primary Sclerosing Cholangitis

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Questions and Answers

Which pattern of liver function tests (LFTs) is typically seen in biliary tract disease?

What is the classic presentation of primary sclerosing cholangitis?

Which autoantibody is typically positive in primary biliary cholangitis?

Which condition is associated with primary biliary cholangitis?

What is the treatment for primary biliary cholangitis?

What is the most common cause of secondary biliary cirrhosis?

What is the pathophysiology of secondary biliary cirrhosis?

Which gender is most commonly affected by primary biliary cholangitis?

What is the most common complication of primary sclerosing cholangitis?

Which autoantibody is typically positive in primary sclerosing cholangitis?

Which condition is characterized by concentric 'onion skin' bile duct fibrosis and alternating strictures and dilation of intra- and extrahepatic bile ducts?

Which condition is associated with ulcerative colitis?

Which condition is characterized by autoimmune reaction leading to destruction of lobular bile ducts?

Which condition is typically seen in middle-aged females?

Which condition is characterized by extrahepatic biliary obstruction and increased pressure in intrahepatic ducts?

Which condition is associated with known obstructive lesions such as gallstones and biliary strictures?

Which condition may present with pruritus, jaundice, dark urine, light-colored stool, and hepatosplenomegaly?

Which condition is characterized by a cholestatic pattern of liver function tests (LFTs) with increased conjugated bilirubin, cholesterol, ALP, and GGT?

Which condition is associated with other autoimmune conditions such as Hashimoto thyroiditis and rheumatoid arthritis?

Which condition can lead to secondary biliary cirrhosis and an increased risk of cholangiocarcinoma and gallbladder cancer?

Which of the following symptoms is commonly seen in biliary tract disease?

Which liver function test (LFT) pattern is typically observed in biliary tract disease?

Which of the following conditions is characterized by concentric 'onion skin' bile duct fibrosis and alternating strictures and dilation of intra- and extrahepatic bile ducts?

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