Podcast
Questions and Answers
What is the probability of a single channel being opened under steady-state conditions?
What is the probability of a single channel being opened under steady-state conditions?
- Po (correct)
- No
- N
- Nc
What must be the sum of the probabilities of a channel being open and closed?
What must be the sum of the probabilities of a channel being open and closed?
- Pc
- N
- 1 (correct)
- No
Which distribution describes the probability of exactly No channels being opened for N channels?
Which distribution describes the probability of exactly No channels being opened for N channels?
- $BN(N_o) = Pc^o (1 - Pc)^{N-N_o}$
- $BN(N_o) = Po^o (1 - Po)^{N-N_o}$ (correct)
- $BN(N_o) = Po + Pc$
- $BN(N_o) = N!N$
What does Pc represent in the context of channel gating statistics?
What does Pc represent in the context of channel gating statistics?
In channel gating statistics, what is the condition for the probability of a channel being open or closed?
In channel gating statistics, what is the condition for the probability of a channel being open or closed?
What type of current is elicited by depolarization from rest?
What type of current is elicited by depolarization from rest?
What current is associated with repolarization?
What current is associated with repolarization?
At what voltage is the charge movement integral of gating current (Q) 20nC?
At what voltage is the charge movement integral of gating current (Q) 20nC?
What does the voltage dependence of the charge movement allow estimation of?
What does the voltage dependence of the charge movement allow estimation of?
According to Boltzman equation, what does the ratio of open to closed channels depend on?
According to Boltzman equation, what does the ratio of open to closed channels depend on?
What is responsible for revealing the voltage-dependence of the channel?
What is responsible for revealing the voltage-dependence of the channel?
What does the symbol 'C' represent in the context of channel gating kinetics?
What does the symbol 'C' represent in the context of channel gating kinetics?
Which formula is used to calculate the open probability of a channel?
Which formula is used to calculate the open probability of a channel?
What does the average dwell time for the channel remaining in the open state represent?
What does the average dwell time for the channel remaining in the open state represent?
In the context of channel gating kinetics, what is the probability density function for the dwell time at the closed state based on?
In the context of channel gating kinetics, what is the probability density function for the dwell time at the closed state based on?
What information can be obtained from fitting dwell time histograms in channel gating kinetics?
What information can be obtained from fitting dwell time histograms in channel gating kinetics?
Which formula is used to calculate the closed probability of a channel?
Which formula is used to calculate the closed probability of a channel?
What is the term used to describe the binary nature of channel gating, where channels exist either in conducting (open) or non-conducting (close or inactivated) state?
What is the term used to describe the binary nature of channel gating, where channels exist either in conducting (open) or non-conducting (close or inactivated) state?
Which type of channels open in response to ligand-binding, mechanical stimulus, and changes in membrane potential?
Which type of channels open in response to ligand-binding, mechanical stimulus, and changes in membrane potential?
What is the term used to describe the loss of channel conductance after activation, even when the activation stimulus is still present?
What is the term used to describe the loss of channel conductance after activation, even when the activation stimulus is still present?
What type of channels are constitutively open and do not require a specific stimulus for their opening?
What type of channels are constitutively open and do not require a specific stimulus for their opening?
How do voltage-gated channels respond to changes in membrane potential?
How do voltage-gated channels respond to changes in membrane potential?
What attracts the positively charged segment of a voltage-gated channel to the negative interior of the cell?
What attracts the positively charged segment of a voltage-gated channel to the negative interior of the cell?
What is the formula for the mean number of open channels?
What is the formula for the mean number of open channels?
How does the variance in the number of open channels relate to the fluctuation in macroscopic channel current?
How does the variance in the number of open channels relate to the fluctuation in macroscopic channel current?
What does the mean macroscopic current formula represent?
What does the mean macroscopic current formula represent?
Which factor influences the 'noise' in channel properties analysis?
Which factor influences the 'noise' in channel properties analysis?
What does the point amplitude histogram help analyze?
What does the point amplitude histogram help analyze?
In the point amplitude histogram, what do the peaks represent?
In the point amplitude histogram, what do the peaks represent?
