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Bethanechol Flashcards
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Bethanechol Flashcards

Created by
@SpellboundEllipsis

Questions and Answers

Which are the trade names for Bethanechol?

  • Duvoid (correct)
  • Urecholine (correct)
  • Urabeth (correct)
  • None of the above

    • What is the pregnancy category of Bethanechol?

    Category C

    What therapeutic class does Bethanechol belong to?

    Urinary tract stimulant

    What is the pharmacological classification of Bethanechol?

    <p>Cholinergics</p> Signup and view all the answers

    What are the indications for using Bethanechol?

    <p>Postpartum and postoperative nonobstructive urinary retention or urinary retention caused by neurogenic bladder.</p> Signup and view all the answers

    What is the main action of Bethanechol?

    <p>Stimulates cholinergic receptors.</p> Signup and view all the answers

    What is one therapeutic effect of Bethanechol?

    <p>Bladder emptying</p> Signup and view all the answers

    How is Bethanechol absorbed after oral administration?

    <p>Poorly absorbed</p> Signup and view all the answers

    Bethanechol crosses the blood-brain barrier.

    <p>False</p> Signup and view all the answers

    What is known about the metabolism and excretion of Bethanechol?

    <p>Unknown</p> Signup and view all the answers

    What is the half-life of Bethanechol?

    <p>Unknown</p> Signup and view all the answers

    What is the onset time for oral administration of Bethanechol?

    <p>30-90 min</p> Signup and view all the answers

    What are contraindications for Bethanechol?

    <p>Hypersensitivity</p> Signup and view all the answers

    What precautions should be taken when administering Bethanechol?

    <p>History of asthma, ulcer disease, cardiovascular disease, epilepsy, hyperthyroidism, and sensitivity to cholinergic agents.</p> Signup and view all the answers

    What are some common adverse reactions to Bethanechol?

    <p>Headache, malaise, lacrimation, bronchospasm, heart block, syncope/cardiac arrest.</p> Signup and view all the answers

    Which medications may interact with Bethanechol?

    <p>Quinidine and procainamide may antagonize cholinergic effects.</p> Signup and view all the answers

    How should Bethanechol be administered?

    <p>PO and SC</p> Signup and view all the answers

    What is the adult oral dosage for Bethanechol?

    <p>25-50 mg 3 times daily</p> Signup and view all the answers

    What is the pediatric oral dosage for Bethanechol?

    <p>0.2 mg/kg 3 times daily or 0.15 mg/kg 4 times daily.</p> Signup and view all the answers

    What are the forms in which Bethanechol is available?

    <p>Tablets and injection.</p> Signup and view all the answers

    What should be monitored in patients taking Bethanechol?

    <p>Monitor BP, pulse, and respirations before and after administration.</p> Signup and view all the answers

    What lab test considerations should be made when using Bethanechol?

    <p>May cause an increase in serum AST, amylase, and lipase concentrations.</p> Signup and view all the answers

    What should be done in case of Bethanechol overdose?

    <p>Treatment includes atropine sulfate.</p> Signup and view all the answers

    Study Notes

    Bethanechol Overview

    • Trade names include Duvoid, Urabeth, and Urecholine.
    • Classified as a Category C drug for pregnancy.
    • Functions as a urinary tract stimulant within the cholinergic pharmacological class.

    Indications and Actions

    • Primarily used for postpartum and postoperative nonobstructive urinary retention, also effective for neurogenic bladder.
    • Stimulates cholinergic receptors, resulting in:
      • Contraction of the urinary bladder
      • Reduced bladder capacity
      • Enhanced ureteral peristaltic waves
      • Increased gastrointestinal peristalsis and gastric secretions

    Pharmacokinetics

    • Poorly absorbed when taken orally, necessitating larger doses compared to subcutaneous administration.
    • Does not penetrate the blood-brain barrier.

    Administration and Dosage

    • Administered orally (PO) or subcutaneously (SC).
    • Adult oral dosage ranges from 25-50 mg three times daily; pediatric dosage is 0.2 mg/kg three times daily.
    • Adult SC dosage is typically 5 mg three to four times daily; pediatric dosage is 0.06 mg/kg three times daily.

    Side Effects and Interactions

    • Common side effects include headache, malaise, lacrimation, bronchospasm, bradycardia, and abdominal discomfort.
    • Life-threatening reactions may involve heart block and syncope.
    • Drug-drug interactions with quinidine and anticholinergics may reduce effectiveness or provoke hypotension.

    Monitoring and Toxicity

    • Monitor blood pressure, pulse, and respiratory rates both pre- and post-administration.
    • Watch for signs of toxicity such as sweating, flushing, and salivation; atropine sulfate is the antidote for overdose.
    • May elevate levels of serum AST, amylase, and lipase in lab tests.

    Availability and Assessment

    • Available in tablet forms of 5 mg, 10 mg, 25 mg, and 50 mg, as well as a 5 mg/mL injection.
    • Assess for bladder distention and postvoid residual as necessary.

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    Description

    Explore essential concepts related to Bethanechol, including trade names, therapeutic class, and indications. These flashcards are perfect for medical students and health professionals looking to reinforce their knowledge on this urinary tract stimulant. Test your understanding of its uses and classifications effectively!

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