Questions and Answers
Which are the trade names for Bethanechol?
What is the pregnancy category of Bethanechol?
Category C
What therapeutic class does Bethanechol belong to?
Urinary tract stimulant
What is the pharmacological classification of Bethanechol?
Signup and view all the answers
What are the indications for using Bethanechol?
Signup and view all the answers
What is the main action of Bethanechol?
Signup and view all the answers
What is one therapeutic effect of Bethanechol?
Signup and view all the answers
How is Bethanechol absorbed after oral administration?
Signup and view all the answers
Bethanechol crosses the blood-brain barrier.
Signup and view all the answers
What is known about the metabolism and excretion of Bethanechol?
Signup and view all the answers
What is the half-life of Bethanechol?
Signup and view all the answers
What is the onset time for oral administration of Bethanechol?
Signup and view all the answers
What are contraindications for Bethanechol?
Signup and view all the answers
What precautions should be taken when administering Bethanechol?
Signup and view all the answers
What are some common adverse reactions to Bethanechol?
Signup and view all the answers
Which medications may interact with Bethanechol?
Signup and view all the answers
How should Bethanechol be administered?
Signup and view all the answers
What is the adult oral dosage for Bethanechol?
Signup and view all the answers
What is the pediatric oral dosage for Bethanechol?
Signup and view all the answers
What are the forms in which Bethanechol is available?
Signup and view all the answers
What should be monitored in patients taking Bethanechol?
Signup and view all the answers
What lab test considerations should be made when using Bethanechol?
Signup and view all the answers
What should be done in case of Bethanechol overdose?
Signup and view all the answers
Study Notes
Bethanechol Overview
- Trade names include Duvoid, Urabeth, and Urecholine.
- Classified as a Category C drug for pregnancy.
- Functions as a urinary tract stimulant within the cholinergic pharmacological class.
Indications and Actions
- Primarily used for postpartum and postoperative nonobstructive urinary retention, also effective for neurogenic bladder.
- Stimulates cholinergic receptors, resulting in:
- Contraction of the urinary bladder
- Reduced bladder capacity
- Enhanced ureteral peristaltic waves
- Increased gastrointestinal peristalsis and gastric secretions
Pharmacokinetics
- Poorly absorbed when taken orally, necessitating larger doses compared to subcutaneous administration.
- Does not penetrate the blood-brain barrier.
Administration and Dosage
- Administered orally (PO) or subcutaneously (SC).
- Adult oral dosage ranges from 25-50 mg three times daily; pediatric dosage is 0.2 mg/kg three times daily.
- Adult SC dosage is typically 5 mg three to four times daily; pediatric dosage is 0.06 mg/kg three times daily.
Side Effects and Interactions
- Common side effects include headache, malaise, lacrimation, bronchospasm, bradycardia, and abdominal discomfort.
- Life-threatening reactions may involve heart block and syncope.
- Drug-drug interactions with quinidine and anticholinergics may reduce effectiveness or provoke hypotension.
Monitoring and Toxicity
- Monitor blood pressure, pulse, and respiratory rates both pre- and post-administration.
- Watch for signs of toxicity such as sweating, flushing, and salivation; atropine sulfate is the antidote for overdose.
- May elevate levels of serum AST, amylase, and lipase in lab tests.
Availability and Assessment
- Available in tablet forms of 5 mg, 10 mg, 25 mg, and 50 mg, as well as a 5 mg/mL injection.
- Assess for bladder distention and postvoid residual as necessary.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Explore essential concepts related to Bethanechol, including trade names, therapeutic class, and indications. These flashcards are perfect for medical students and health professionals looking to reinforce their knowledge on this urinary tract stimulant. Test your understanding of its uses and classifications effectively!