Betalactam Antibiotics Learning Quiz
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Questions and Answers

What are the specific learning outcomes regarding Betalactam antibiotics according to Dr. Nazmun Nahar Alam?

The specific learning outcomes include describing the mechanism of action, therapeutic uses, adverse effects and limitations of crystalline penicillin / penicillin G, listing the long acting penicillins with their duration of action and uses, listing different groups of semisynthetic penicillins with examples, advantages over penicillin G and uses, listing and describing the role of betalactamases inhibitors in the treatment of bacterial infections, and listing the different generations of cephalosporins with 2 examples for each and stating their mechanism of action, uses and adverse effects.

What are the classifications of antimicrobial agents (AMA) based on chemical group?

The classifications include Penicillins (Penicillin G, Amoxicillin), Cephalosporins (Cephalexin, Cefotaxime), β-lactam antibiotics, Macrolides (Erythromycin, Azithromycin), Aminoglycosides (Streptomycin, Gentamicin), Tetracyclines (Doxycycline, Minocycline), Fluoroquinolones (Ciprofloxacin, Ofloxacin), and Others (Sulphonamides, Trimethoprim, Rifampicin, Metronidazole).

What are the different types of β-Lactam antibiotics mentioned in the text?

The different types of β-Lactam antibiotics mentioned are Penicillins, Cephalosporins, Carbapenems, and Monobactams.

What is the role of betalactamase inactivation in β-lactam antibiotics?

<p>The betalactamase enzyme hydrolyses the β-lactam ring in the antibiotic, leading to the inactivation of the antibiotic.</p> Signup and view all the answers

List two examples of each generation of cephalosporins and state their mechanism of action, uses, and adverse effects.

<p>First generation: Cefazolin, Cephalexin - Mechanism of action: Inhibits bacterial cell wall synthesis; Uses: Treatment of mild-to-moderate infections caused by susceptible Gram-positive organisms; Adverse effects: GI disturbances, allergic reactions. Second generation: Cefuroxime, Cefoxitin - Mechanism of action: Inhibits bacterial cell wall synthesis; Uses: Treatment of respiratory and urinary tract infections; Adverse effects: Diarrhea, allergic reactions.</p> Signup and view all the answers

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