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Beta Thalassemia Variants Summary
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Beta Thalassemia Variants Summary

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Questions and Answers

What is the likely consistency of an enlarged lymph node in a patient with suspected malignancy?

  • Soft
  • Hard (correct)
  • Tender
  • Rubbery
  • Which condition is associated with painful lymphadenopathy?

  • Thyroid disease
  • Viral infections
  • Malignant lymphoma (correct)
  • Systemic lupus erythematosus
  • In liver cirrhosis, what clinical feature is commonly observed?

  • Hypotension
  • Hypoglycemia
  • Jaundice (correct)
  • Hyperkalemia
  • Which type of Thalassemia involves three defective alleles?

    <p>Hemoglobin H disease</p> Signup and view all the answers

    What is the composition of Hemoglobin Bart's disease?

    <p>Four gamma-chains (gamma-tetramers)</p> Signup and view all the answers

    Which condition results from a combination of one defective beta-globin allele and one defective HbS allele?

    <p>Sickle cell beta thalassemia</p> Signup and view all the answers

    What distinguishes Beta-thalassemia major from Beta-thalassemia minor?

    <p>Severity of clinical symptoms</p> Signup and view all the answers

    What characteristic differentiates normal lymph nodes from those infected?

    <p>Size; &lt; 1 cm vs &gt; 1 cm</p> Signup and view all the answers

    Which condition is commonly associated with acute lymph node enlargement without long-term progression?

    <p>Inflammatory causes</p> Signup and view all the answers

    What is the consistency of lymphadenopathy in mycobacterial causes?

    <p>Rubbery</p> Signup and view all the answers

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