Beta Thalassemia Variants Summary

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10 Questions

What is the likely consistency of an enlarged lymph node in a patient with suspected malignancy?

Hard

Which condition is associated with painful lymphadenopathy?

Malignant lymphoma

In liver cirrhosis, what clinical feature is commonly observed?

Jaundice

Which type of Thalassemia involves three defective alleles?

Hemoglobin H disease

What is the composition of Hemoglobin Bart's disease?

Four gamma-chains (gamma-tetramers)

Which condition results from a combination of one defective beta-globin allele and one defective HbS allele?

Sickle cell beta thalassemia

What distinguishes Beta-thalassemia major from Beta-thalassemia minor?

Severity of clinical symptoms

What characteristic differentiates normal lymph nodes from those infected?

Size; < 1 cm vs > 1 cm

Which condition is commonly associated with acute lymph node enlargement without long-term progression?

Inflammatory causes

What is the consistency of lymphadenopathy in mycobacterial causes?

Rubbery

Learn about the minor and major variants of beta thalassemia, along with the sickle cell beta thalassemia. Understand the clinical features, complications, and differences between these variants.

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