Podcast
Questions and Answers
What is the mechanism of action of penicillins?
What is the mechanism of action of penicillins?
- Disruption of bacterial cell membrane
- Inhibition of DNA gyrase
- Inhibition of bacterial protein synthesis
- Inhibition of transpeptidation reaction by binding to PBPs (correct)
Which bacteria are commonly targeted by antipseudomonal penicillins?
Which bacteria are commonly targeted by antipseudomonal penicillins?
- Streptococci and staphylococci
- Pseudomonas aeruginosa and Klebsiella pneumoniae (correct)
- Moraxella and Haemophilus influenzae
- Salmonella and Shigella
What is the spectrum of activity of aminopenicillins?
What is the spectrum of activity of aminopenicillins?
- Viral pathogens
- Primarily gram-negative bacteria
- Primarily gram-positive bacteria (correct)
- Intracellular bacteria
What is the target site of cephalosporins' action?
What is the target site of cephalosporins' action?
Which type of killing is associated with bactericidal antibiotics like penicillins and cephalosporins?
Which type of killing is associated with bactericidal antibiotics like penicillins and cephalosporins?
What mechanism of resistance to vancomycin is attributed to VRSA?
What mechanism of resistance to vancomycin is attributed to VRSA?
Which antibiotic has a spectrum of activity that includes MRSA, VISA, and VRSA?
Which antibiotic has a spectrum of activity that includes MRSA, VISA, and VRSA?
Which antibiotic is known for its unintended effects such as myopathy, rhabdomyolysis, and jaundice?
Which antibiotic is known for its unintended effects such as myopathy, rhabdomyolysis, and jaundice?
What is the primary mechanism of action of polymyxin B?
What is the primary mechanism of action of polymyxin B?
Which antibiotic is specifically mentioned for treating acute cystitis and urinary tract infections caused by E. coli and Enterococcus faecalis?
Which antibiotic is specifically mentioned for treating acute cystitis and urinary tract infections caused by E. coli and Enterococcus faecalis?
Which antibiotic acts by inhibiting the incorporation of amino acids into the bacterial cell wall?
Which antibiotic acts by inhibiting the incorporation of amino acids into the bacterial cell wall?
Which of the following statements about penicillins is correct?
Which of the following statements about penicillins is correct?
Which route of administration is NOT mentioned for penicillin G in the text?
Which route of administration is NOT mentioned for penicillin G in the text?
Based on the information provided, which of the following statements is true about benzathine penicillin G suspension?
Based on the information provided, which of the following statements is true about benzathine penicillin G suspension?
Which of the following penicillins is specifically mentioned as being available for oral administration?
Which of the following penicillins is specifically mentioned as being available for oral administration?
Which cephalosporin is specifically indicated for infections caused by MRSA, VISA, and VRSA?
Which cephalosporin is specifically indicated for infections caused by MRSA, VISA, and VRSA?
Which cephalosporin is effective against Neisseria gonorrhoeae and used in the treatment of gonorrhea?
Which cephalosporin is effective against Neisseria gonorrhoeae and used in the treatment of gonorrhea?
Which cephalosporin is known for its extended gram-negative activity and is classified as 3rd generation?
Which cephalosporin is known for its extended gram-negative activity and is classified as 3rd generation?
Which subclass of 2nd generation cephalosporins include antibiotics like Cefoxitin and Cefotetan?
Which subclass of 2nd generation cephalosporins include antibiotics like Cefoxitin and Cefotetan?
Which cephalosporin has the broadest spectrum of activity among cephalosporins and is specifically effective against Pseudomonas, Enterobacter, and Bacteroides?
Which cephalosporin has the broadest spectrum of activity among cephalosporins and is specifically effective against Pseudomonas, Enterobacter, and Bacteroides?
Which generation of cephalosporins includes antibiotics like Cefprozil and Cefuroxime axetil, with a spectrum of activity covering Haemophilus influenzae and Moraxella catarrhalis?
Which generation of cephalosporins includes antibiotics like Cefprozil and Cefuroxime axetil, with a spectrum of activity covering Haemophilus influenzae and Moraxella catarrhalis?
Which mechanism of antibiotic resistance is NOT mentioned in the text?
Which mechanism of antibiotic resistance is NOT mentioned in the text?
What is the primary reason for the contraindication of β-lactam antibiotics, besides previous β-lactam allergy?
What is the primary reason for the contraindication of β-lactam antibiotics, besides previous β-lactam allergy?
Which of the following is NOT a characteristic of carbapenem antibiotics as described in the text?
Which of the following is NOT a characteristic of carbapenem antibiotics as described in the text?
What is the primary mechanism of action of vancomycin, as described in the text?
What is the primary mechanism of action of vancomycin, as described in the text?
Which of the following is NOT a spectrum of activity or use for vancomycin, as described in the text?
Which of the following is NOT a spectrum of activity or use for vancomycin, as described in the text?
What is the primary route of administration for vancomycin when used for systemic Gram-positive infections, according to the text?
What is the primary route of administration for vancomycin when used for systemic Gram-positive infections, according to the text?